Estimation of the combined response to treatment in multicenter trials

Journal of Biopharmaceutical Statistics

Volumn 11, Issue 4, 2001, Pages 275-295

  Dragalin, Vladimir ^a   Fedorov, Valerii ^a   Jones, Byron ^a   Rockhold, Frank ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Clustering; Combined response to treatment; Model validity range; Multicenter trial

Indexed keywords

PSYCHOTROPIC AGENT;

ARTICLE; CLUSTER ANALYSIS; MENTAL DISEASE; METHODOLOGY; MULTICENTER STUDY; PRIORITY JOURNAL; SIMULATION; STATISTICAL ANALYSIS; STATISTICAL MODEL; TREATMENT OUTCOME; VALIDATION PROCESS;

EID: 0035560472     PISSN: 10543406     EISSN: None     Source Type: Journal    
DOI: 10.1081/BIP-120008849     Document Type: Article

References (16)

1. Evaluation of multicenter clinical trial data using adaptations of the Mosteller-Tukey procedure
2. Tests for qualitative treatment-by-center interaction using 'pushback' procedure
3. Optimal design and the model validity range
4. Analysis of data from multiclinic trials
5. Center-weighting issues in multicenter clinical trials
6. Multi-center trial analysis revisited
7. ICH harmonised tripartite guideline: Statistical principles for clinical trials
8. A comparison of various estimators of treatment difference for a multi-center clinical trial
9. Treatment-by-center interaction: What is the issue?
10. An issue of statistical analysis in controlled multi-center studies: How shall we weight the centers?
11. The number of centers in a multicenter clinical study: Effects on statistical power
12. Combination of results of stated precision: II. A more realistic case
13. General linear models for multicenter clinical trials
14. Some controversies in planning and analysing multi-center trials