E-cadherin as a prognostic indicator in primary breast cancer

British Journal of Cancer

Volumn 85, Issue 12, 2001, Pages 1958-1963

  Parker, C ^a   Rampaul, R S ^a   Pinder, S E ^a   Bell, J A ^a   Wencyk, P M ^a   Blamey, R W ^a   Nicholson, R I ^b   Robertson, J F R ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b Tenovus Institute   (Canada)

Author keywords

Breast cancer; Cadherin; Immunohistochemistry; Prognosis

Indexed keywords

MONOCLONAL ANTIBODY; UVOMORULIN;

ADULT; AGED; ARTICLE; BREAST CARCINOMA; CANCER GRADING; CANCER INVASION; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CELL CONTACT; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TUMOR CELL; TUMOR VOLUME; VASCULAR DISEASE;

EID: 0035555657     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2001.2178     Document Type: Article

References (36)

1. Identification of eleven novel tumour-associated E-cadherin mutations. Mutations in brief no. 215. Online
2. The role of cell adhesion molecules in cancer invasion and metastasis
3. E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain
4. Cadherin expression in carcinomas: Role in the formation of cell junctions and the prevention of invasiveness
5. Tamoxifen restores the E-Cadherin function in human breast cancer MCF-7/6 cells and suppresses their invasive phenotype
6. Transcriptional regulation of the human E-cadherin gene in human prostate cancer cell lines: Characterisation of the human E-Cadherin gene promoter
7. E-Cadherin quantitative immunocytochemical assays in breast carcinomas
8. E-Cadherin expression in colorectal cancer: An immunocytochemical and In Situ hybridisation study
9. Pathological prognostic factors in breast cancer. II. Histological types. Relationship with survival in a large study with long term follow up
10. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: Experience from a large study with long-term follow-up
11. Correlation of E-cadherin expression with differentiation grade and histological type in breast cancer
12. An immunohistochemical examination of the expression of E-Cadherin, a-and b/y -Catenins, and a2 and b1-Integrins in invasive breast cancer
13. E-Cadherin expression in duct carcinoma In Situ (DCIS) of the breast
14. Expression of β-catenin in normal breast tissue and breast carcinoma: A comparative study with epithelial cadherin and α-catenin
15. Mechanisms of inactivation of E-Cadherin in breast cancer cell lines
16. Loss of E-Cadherin expression associated with lymph node metastases in small breast carcinomas
17. From cadherins to catenins: Cytoplasmic protein interactions and regulation of cell adhesion
18. H-Cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer
19. Expression of E-Cadherin as related to other prognostic factors and survival in breast cancer
20. Assay of E-Cadherin by ELISA in human breast cancers
21. Down-regulation of E-Cadherin expression in madin darby canine kidney cells inside tumours of nude mice
22. E-Cadherin expression in primary and metastatic gastric cancer: Down-regulation correlates with cellular dedifferentiation and glandular disintegration
23. Role of morphogenetic factors in metastasis of mammary carcinoma cells
24. Differential loss of E-Cadherin expression in infiltrating ductal and lobular breast carcinomas
25. Expression of E-Cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis
26. Pathological prognostic factors in breast cancer IV. Should you be a typer or grader? A comparative study of two prognostic variables in operable breast cancer
27. A causal role for E-Cadherin in the transition from adenoma to carcinoma
28. Pathological prognostic factors in breast cancer. III. Vascular invasion: Relationship with recurrence and survival in a large study with long-term follow-up
29. E-Cadherin expression in basal cell carcinoma
30. Epithelial (E-) and placental (P-) cadherin cell adhesion molecule expression in breast carcinoma
31. Reduced α-catenin and E-cadherin expression in breast cancer
32. Pathology reporting in breast cancer screening
33. E-Cadherin expression in squamous cell carcinomas of the head and neck: Inverse correlation with tumour dedifferentiation and lymph node metastasis
34. Cadherin dysfunction in a human cancer cell line: Possible involvement of loss of α-catenin expression in reduced cell-cell adhesiveness
35. Reduced E-Cadherin expression is associated with invasiveness and unfavourable prognosis in breast cancer
36. L-CAM expression in normal. Premalignant and malignant colon mucosa