Pancreatitis-Associated Protein Levels in Pancreatic Juice from Patients with Pancreatic Diseases

Pancreatology

Volumn 1, Issue 1, 2001, Pages 43-47

  Motoo, Yoshiharu ^a   Watanabe, Hiroyuki ^a   Yamaguchi, Yasushi ^a   Xie, Min Jue ^a   Mouri, Hisatsugu ^a   Ohtsubo, Koushiro ^a   Okai, Takashi ^a   Wakabayashi, Tokio ^b   Sawabu, Norio ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b Ishikawa Pref Saiseikai Kanazawa H ^*  (Japan)

Author keywords

Apoptosis; Chronic pancreatitis; Pancreatic cancer; Pancreatic juice; Pancreatitis associated protein (PAP)

Indexed keywords

ACUTE PHASE PROTEIN; BIOLOGICAL MARKER; LECTIN; PANCREATITIS ASSOCIATED PROTEIN; PANCREATITIS-ASSOCIATED PROTEIN; TUMOR ANTIGEN; TUMOR MARKER;

ARTICLE; CHEMISTRY; CHRONIC DISEASE; COMPARATIVE STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; MIDDLE AGED; PANCREAS DISEASE; PANCREAS JUICE; PANCREAS TUMOR; PANCREATITIS; PATHOLOGY; PATHOPHYSIOLOGY; PREDICTION AND FORECASTING; REFERENCE VALUE;

ACUTE-PHASE PROTEINS; ANTIGENS, NEOPLASM; BIOLOGICAL MARKERS; CHRONIC DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LECTINS, C-TYPE; MIDDLE AGED; PANCREATIC DISEASES; PANCREATIC JUICE; PANCREATIC NEOPLASMS; PANCREATITIS; PREDICTIVE VALUE OF TESTS; REFERENCE VALUES; TUMOR MARKERS, BIOLOGICAL;

EID: 0035552557     PISSN: 14243903     EISSN: 14243911     Source Type: Journal    
DOI: 10.1159/000055791     Document Type: Article

References (31)

1. Lovanna JL, Keim V, Michel R, et al: Pancreatic gene expression is altered during acute experimental pancreatitis in the rat. Am J Phys 1991;261:G485-489.
2. Keim V, Lovanna JL, Dagorn JC: The acute phase reaction of the exocrine pancreas: Gene expression and synthesis of pancreatitis-associated proteins. Digestion 1994;55:65-72.
3. Lovanna JL, Keim V, Nordback I, et al: Serum levels of pancreatitis-associated protein as indicators of the course of acute pancreatitis. Gastroenterology 1994;106:728-734.
4. Motoo Y, Satomura Y, Mouri I, et al: Serum levels of pancreatitis-associated protein in digestive diseases with special reference to gastrointestinal cancers. Dig Dis Sci 1999;44: 1142-1147.
5. Itoh T, Sawabu N, Motoo Y, et al: The human pancreatitis-associated protein (PAP)-encoding gene generates multiple transcripts through alternative use of 5′-exons. Gene 1995;155: 283-287.
6. Motoo Y, Itoh T, Su SB, et al: Expression of pancreatitis-associated protein (PAP) mRNA in gastrointestinal cancers. Int J Pancreatol 1998;25:11-16.
7. Lasserre C, Christa L, Simon M-T, et al: A novel gene (HIP) activated in human primary liver cancer. Cancer Res 1992;52:5089-5095.
8. Dusetti NJ, Montalto G, Ortiz EM, et al: Mechanism of PAP I gene induction during hepatocarcinogenesis: Clinical implications. Br J Cancer 1996;74:1767-1775.
9. Montalto G, Lovanna JL, Soresi M, et al: Clinical evaluation of pancreatitis-associated protein as a serum marker of hepatocellular carcinoma: Comparison with alpha-fetoprotein. Oncology 1998;55:421-425.
10. Takemori Y, Sawabu N, Ohta H, et al: Evaluation of cancer-associated carbohydrate antigen (NCC-ST-439) measurement in pure pancreatic juice collected by endoscopie aspiration. Dig Endosc 1990;2:141-147.
11. Wakabayashi T, Sawabu N, Takemori Y, et al: Diagnostic significance of cancer-associated carbohydrate antigen (CA19-9) concentrations in pancreatic juice. Pancreas 1993;8:151-159.
12. Ohta H, Sawabu N, Takemori Y, et al: Measurement of sialylated stage-specific embryonic antigen-1 in pure pancreatic juice for the diagnosis of pancreatic cancer. Int J Pancreatol 1994;15:35-41.
13. Watanabe H, Yamguchi Y, Ha A, et al: Quantitative determination of K-ras mutations in pancreatic juice for diagnosis of pancreatic cancer using hybridization protection assay. Pancreas 1998;17:341-347.
14. Yamaguchi Y, Watanabe H, Songür Y, et al: Detection of mutations of p53 tumor suppressor gene in pancreatic juice and its application to the diagnosis of patients with pancreatic cancer: Comparison with K-ras mutation. Clin Cancer Res 1999;5:1147-1153.
15. Schmiegel W, Burchert M, Kalthoff H, et al: Immunochemical characterization and quantitative distribution of pancreatic stone protein in sera and pancreatic secretions in pancreatic disorders. Gastroenterology 1990;99:1421-1430.
16. Mariani A, Mezzi G, Malesci A: Purification of secretory lithostathine in human pancreatic juice by fast protein liquid chromatography. Gut 1995;36:622-629.
17. Keim V, Rohr G, Stöckert HG, et al: An additional secretory protein in the rat pancreas. Digestion 1984;29:242-249.
18. Keim V, Lovanna JL, Orelle B, et al: A novel exocrine protein associated with pancreas transplantation in humans. Gastroenterology 1992;103:248-254.
19. Japan Pancreas Society: Classification of Pancreatic Carcinoma, 1st English ed. Tokyo, Kanehara, 1996, pp 3-14.
20. The Diagnosis Criteria Committee of the Japan Pancreas Society: Final report of clinical diagnostic criteria of chronic pancreatitis (in Japanese). J Jpn Pane Soc 1995;10:xxiii-xxvi.
21. Kemppainen E, Sand J, Puolakkainen P, Laine S, Hedström J, Sainio V, Haapiainen R, Nordback I: Pancreatitis associated protein as an early marker of acute pancreatitis. Gut 1996; 39:675-678.
22. Bellone G, Smirne C, Carbone A, et al: Production and pro-apoptotic activity of soluble CD95 ligand in pancreatic carcinoma. Clin Cancer Res 2000;6:2448-2455.
23. Bernstorff WV, Spanjaard RA, Chan AK, et al: Pancreatic cancer cells can evade immune surveillance via nonfunctional Fas (APO-1/CD95) receptors and aberrant expression of functional Fas ligand. Surgery 1999;125:73-84.
24. Kitahara F, Kobayashi K, Sato T, et al: Accuracy of screening for gastric cancer using serum pepsinogen concentrations. Gut 1999;44:693-697.
25. Sand JA, Hyoty MK, Manila J, et al: Clinical assessment compared with cyst fluid analysis in the differential diagnosis of cystic lesions in the pancreas. Surgery 1996;119:275-280.
26. Ortiz EM, Dusetti NJ, Vasseur S, et al: The pancreatitis-associated protein is induced by free radicals in AR4-2J cells and confers cell resistance to apoptosis. Gastroenterology 1998; 114:808-816.
27. Malka D, Vasseur S, Bödeker H, et al: Tumor necrosis factor a triggers antiapoptotic mechanisms in rat pancreatic cells through pancreatitis-associated protein I activation. Gastroenterology 2000;119:816-828.
28. Satoh K, Shimosegawa T, Masamune A, et al: Fas ligand is frequently expressed in human pancreatic duct cell carcinoma. Pancreas 1999; 19:339-345.
29. Christa L, Simon M-T, Brezault-Bonnet C, et al: Hepatocarcinoma-intestine-pancreas/pancreatic associated protein (HIP/PAP) is expressed and secreted by proliferating ductules as well as by hepatocarcinoma and cholangio-carcinoma cells. Am J Pathol 1999;155:1525-1533.
30. Keim V, Hoffmeister A, Teich N, et al: The pancreatitis-associated protein in hereditary and chronic alcoholic pancreatitis. Pancreas 1999;19:248-254.
31. Morissct J, Iovanna J, Grondin G: Localization of rat pancreatitis-associated protein during bile salt-induced pancreatitis. Gastroenterology 1997;112:543-550.