Expression of pancreatitis-associated protein (PAP) mRNA in gastrointestinal cancers

International Journal of Pancreatology

Volumn 23, Issue 1, 1998, Pages 11-16

  Motoo, Yoshiharu ^a   Itoh, Takako ^b   Su, Shi Bing ^a   Nakatani, Márcia Tiemi ^a   Watanabe, Hiroyuki ^a   Okai, Takashi ^a   Sawabu, Norio ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b SHIONOGI AND CO LTD   (Japan)

Author keywords

Dedifferentiation; Ectopic expression; Gastrointestinal cancers; In situ hybridization (ISH); Pancreatitis associated protein (PAP)

Indexed keywords

MESSENGER RNA;

ACUTE PANCREATITIS; ARTICLE; CELL DIFFERENTIATION; COLORECTAL CANCER; DIGESTIVE SYSTEM CANCER; DNA PROBE; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; LIVER CELL CARCINOMA; MOLECULAR CLONING; PANCREATITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER;

ACUTE-PHASE PROTEINS; ANTIGENS, NEOPLASM; GASTROINTESTINAL NEOPLASMS; HUMANS; IN SITU HYBRIDIZATION; LECTINS, C-TYPE; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL;

EID: 0031936483     PISSN: 01694197     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Keim V, Rohr G, Stocker HG, Haberich FJ. An additional secretory protein in the rat pancreas. Digestion 1984; 29: 242-249.
2. Iovanna J, Orelle B, Keim V, Dagorn JC. Messenger RNA sequence and expression of rat pancreatitis-associated protein, a lectin-related protein overexpressed during acute experimental pancreatitis. J Biol Chem 1991; 226: 24,664-24,669.
3. Keim V, Iovanna J-L, Orelle B, Verdier J-M, Busing M, Hopt U, Dagorn J-C. A novel exocrine protein associated with pancreas transplantation in humans. Gastroenterology 1992; 103: 248-254.
4. Orelle B, Keim V, Masciotra L, Dagorn JC. Iovanna JL. Human pancreatitis-associated protein: messenger RNA cloning and expression in pancreatic diseases. J Clin Invest 1992; 90: 2284-2291.
5. Itoh T, Teraoka H, Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP). Biochim Biophys Acta 1993; 1172: 184-186.
6. Dusetti NJ, Frigerio J-M, Keim V, Dagorn J-C, Iovanna JL. Structural organization of the gene encoding the rat pancreatitis-associated protein: analysis of its evolutionary history reveals an ancient divergence from the other carbohydrate-recognition domain-containing genes. J Biol Chem 1993; 268: 14,470-14,475.
7. Dusetti NJ, Frigerio J-M, Fox MF, Swallow DM, Dagorn J-C, Iovanna JL. Molecular cloning, genomic organization, and chromosomal localization of the human pancreatitis-associated protein (PAP) gene. Genomics 1994; 19: 108-114.
8. Iovanna J-L, Férec C, Sarles J, Dagorn J-C. The pancreatitis-associated protein (PAP). A new candidate for neonatal screening of cystic fibrosis. C R Acad Sci Paris 1994; 317: 561-564.
9. Lasserre C, Christa L, Simon MT, Vernier P, Brechot C. A novel gene (HIP) activated in human primary liver cancer. Cancer Res 1992; 52: 5089-5095.
10. Lasserre C, Simon M-T, Ishikawa H, Diriong S, Nguyen VC, Christa L, Vernier P, Brechot C. Structural organization and chromosomal localization of a human gene (HIP/PAP) encoding a C-type lectin overexpressed in primary liver cancer. Eur J Biochem 1994; 224: 29-38.
11. Itoh T, Sawabu N, Motoo Y, Funakoshi A, Teraoka H. The human pancreatitis-associated protein (PAP)-encoding gene generates multiple transcripts through alternative use of 5′ exons. Gene 1995; 155: 283-287.
12. Chakraborty C, Sharma S, Katsumata N, Murphy LJ, Schroedter IC, Robertson MC, Shiu RPC, Friesen HG. Plasma clearance, tissue uptake and expression of pituitary peptide 23/pancreatitis-associated protein in the rat. J Endocrinol 1995; 145: 461-469.
13. Motoo Y, Yamaguchi Y, Sawabu N. Expression of multidrug resistance gene (mdr-1) mRNA in human hepatoma cell lines: analysis with nonisotopic in situ hybridization. Int Hepatol Commun 1993; 1: 170-173.
14. Hayashi D. Study on the expression of oncogene mRNA in hepatocellular carcinoma using in situ hybridization technique. Jpn J Surg 1994;95:814-822(in Japanese with English abstract).
15. Yamada S, Takahashi M, Hara M, Sano T, Aiba T, Shishiba Y, Suzuki T, Asa SL. Growth hormone and prolactin gene expression in human densely and sparsely granulated somatotroph adenomas by in situ hybridization with digoxigenin-labeled probes. Diag Mol Pathol 1994; 3: 46-52.
16. Ono M, Sakamoto M, Ino Y, Moriya Y, Sugihara K, Muto T, Hirohashi S. Cancer cell morphology at the invasive front and expression of cell adhesion-related carbohydrate in primary lesion of patients with colorectal carcinoma with liver metastasis. Cancer 1996; 78: 1179-1186.
17. Japanese Research Society for Gastric Cancer. The general rules for the gastric cancer study in surgery and pathology. Jpn J Surg 1981; 11: 127-139.
18. Japanese Research Society for Cancer of the Colon and Rectum. General rules for clinical and pathological studies on cancer of the colon, rectum and anus. Jpn J Surg 1983; 13: 574-598.
19. Keim V, Iovanna J-L, Dagorn J-C. The acute phase reaction of the exocrine pancreas: gene expression and synthesis of pancreatitis-associated proteins. Digestion 1994; 55: 65-72.
20. Keim V, Willemer S, Iovanna J-L, Adler G, Dagorn J-C. Rat pancreatitis-associated protein is expressed in relation to severity of experimental pancreatitis. Pancreas 1994; 9: 606-612.
21. Iovanna J-L, Keim V, Nordback I, Montalto G, Camarena J, Letoublon C, Lévy P, Berthézène P, Dagorn J-C. Serum levels of pancreatitis-associated protein as indicators of the course of acute pancreatitis. Gastroenterology 1994; 106: 728-734.
22. McKie AT, Simpson RJ, Ghosh S, Peters TJ, Farzaneh F. Regulation of pancreatitis-associated protein (HIP/PAP) mRNA levels in mouse pancreas and small intestine. Clin Sci 1996; 91: 213-218.
23. Christa L, Felin M, Morali O, Simon M-T. Lasserre C, Brechot C, Sève A-P. The human HIP gene, overexpressed in primary liver cancer encodes for a C-type carbohydrate binding protein with lactose binding activity. FEBS Lett 1994; 337: 114-118.
24. Dusetti NJ, Montalto G, Ortiz EM, Masciotra L, Dagorn J-C, Iovanna JL. Mechanism of PAP I gene induction during hepatocarcinogenesis: clinical implications. Br J Cancer 1996; 74: 1767-1775.
25. Iovanna JL, Keim V, Bosshard A, Orelle B, Frigerio J-M, Dusetti N, Dagorn J-C. PAP, a pancreatic secretory protein induced during acute pancreatitis, is expressed in rat intestine. Am J Physiol (Gastrointest Liver Physiol 28) 1993; 265: G611-618.
26. Masciotra L, Lechêne de la Porte P, Frigerio J-M, Dusetti NJ, Dagorn J-C, Iovanna JL. Immunocytochemical localization of pancreatitis-associated protein in human small intestine. Dig Dis Sci 1995; 40: 519-524.
27. Dusetti NJ, Mallo GV, Ortiz EM, Keim V, Dagorn J-C, Iovanna JL. Induction of lithostathine/reg mRNA expression by serum from rats with acute pancreatitis and cytokines in pancreatic acinar AR-42J cells. Archiv Biochem Biophys 1996; 330: 129-132.
28. Iovanna JL, Lechêne de la Porte P, Dagorn J-C. Expression of genes associated with dedifferentiation and cell proliferation during pancreatic regeneration following acute pancreatitis. Pancreas 1992; 7: 712-718.
29. Motoo Y, Sawabu N, Nakanuma Y. Expression of epidermal growth factor and fibroblast growth factor in human hepatocellular carcinoma: an immunohistochemical study. Liver 1991; 11: 272-277.
30. Yasumoto K, Okamoto S, Mukaida N, Murakami S, Mai M, Matsushima K, Tumor necrosis factor α and interferon γ synergistically induce interleukin 8 production in a human gastric cancer cell line through acting concurrently on AP-1 and NF-κB-like binding sites of the interleukin 8 gene. J Biol Chem 1992; 267: 22,506-22,511.
31. Matsushima K, Baldwin ET, Mukaida N. Interleukin-8 and MCAF: novel leukocyte recruitment and activating cytokines, in: Interleukins: Molecular Biology and Immunology, Kishimoto T, ed. Chem Immunol,. Karger, Basel, 1992: pp. 236-565.
32. Gewirtz G, Yalow RS. Ectopic ACTH production in careinoma of the lung. J Clin Invest 1974; 53: 1022-1026.
33. Watanabe H, Tokuyama H, Ohta H, Satomura Y, Okai T, Ooi A, Mai M, Sawabu N. Expression of placental alkaline phosphatase in gastric and colorectal cancers: an immunohistochemical study using the prepared monoclonal antibody. Cancer 1990; 66: 2575-2582.
34. Satomura Y, Sawabu N, Ohta H, Watanahe H, Yamakawa O, Motoo Y, Okai T, Toya D, Makino H, Okamoto H. The immunohistochemical evaluation of PSP/reg-protein in normal and diseased human pancreatic tissues, Int J Pancreatol 1993; 13:59-67.
35. Satomura Y, Sawabu N, Mouri I, Yamakawa O, Watanabe H, Motoo Y, Okai T, Iton T, Kaneda K, Okamoto H. Measurement of serum PSP/reg-protein concentration in various diseases with a newly developed enzyme-linked immunosorbent assay. J Gastroenterol 1995; 30: 643-650.
36. Dusetti NJ, Ortiz EM, Dagorn J-C, Iovanna JL. Identification of a transcriptional region of the rat pancreatitis-associated protein I (PAP I) gene that confers tissue specificity. Biochem J 1995; 311: 643-647.
37. Dusetti NJ, Ortiz EM, Mallo GV, Dagorn J-C, Iovanna JL. Pancreatitis-associated protein I (PAP I), an acute phase protein induced by cytokines: identification of two functional interleukin-6 response elements in the rat PAP I promoter region. J Biol Chem 1995; 270: 22,417-22,421.