Palladium-catalyzed reductive dimerizations of highly functionalized allenes

Chemistry Letters

Volumn , Issue 12, 2001, Pages 1288-1289

  Oh, Chang Ho ^a   Yoo, Hee Sang ^a   Jung, Seung Hyun ^a  

^a Hanyang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035528545     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.2001.1288     Document Type: Article

References (21)

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21. General procedure for dimerization/reduction of 1a: In a 5-mL round-bottomed flask were placed allene 1 (70.2 mg, 0.821 mmol) and tetrakis(triphenylphosphine)palladium(0) (10.3 mg, 0.0088 mmol). Dry DMF(1.5 mL) was added to the above mixture by a syringe under argon atmosphere. And then formic acid (39 μL, 0.992 mmol) was added to the reaction mixture by a microsyringe at 0 °C. The reaction mixture was stirred for 12 h in a preheated 30 °C oil bath. Then extractive work-up and solvent evaporation under reduced pressure gave the crude products which were purified on flash column chromatography (eluent: hexane/ethyl acetate (1:1)) to give a 1: 1 mixture of 2a and 3a (overall 33.4 mg, 48%) as colorless oil.