Relation between soluble adhesion molecules and insulin sensitivity in type 2 diabetic individuals: Role of adipose tissue

Diabetes Care

Volumn 24, Issue 11, 2001, Pages 1961-1966

  Targuer, Giovanni ^a   Bonadonna, Riccardo C ^a   Alberiche, Maria ^a   Zenere, Marina B ^a   Muggeo, Michele ^a   Bonora, Enzo ^a,b  

^a UNIVERSITY OF VERONA   (Italy)

^b UNIVERSITY HOSPITAL OF VERONA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLATED HEMOGLOBIN; INTERCELLULAR ADHESION MOLECULE 1; SELECTIN; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; AGED; ANTHROPOMETRY; ARTICLE; BLOOD; BLOOD PRESSURE; BODY MASS; CLINICAL TRIAL; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; HUMAN; HYPERINSULINISM; INSULIN RESISTANCE; MALE; METABOLISM; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOPHYSIOLOGY; PHYSIOLOGY; REFERENCE VALUE; REGRESSION ANALYSIS;

ADULT; AGED; ANTHROPOMETRY; BLOOD GLUCOSE; BLOOD PRESSURE; BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOSE CLAMP TECHNIQUE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPERINSULINISM; INSULIN RESISTANCE; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; REFERENCE VALUES; REGRESSION ANALYSIS; SELECTINS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0035512784     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.24.11.1961     Document Type: Article

References (17)

1. Lusis AJ: Atherosclerosis. Nature 407:233-241, 2000.
2. Gearing AJH, Newman W: Circulating adhesion molecules in disease. Immunol Today 14:506-512, 1993
3. Cines DB, Pollak ES, Buck CA, Loscalzo J, Zimmerman GA, McEver RP, Pober JS, Wick TM, Konkle BA, Schwartz BS, Barnathan ES, McCrae KR, Hug BA, Schmidt AM, Stem DM: Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 91:3527-3561, 1998
4. Ridker PM, Hennekens CH, Roitman-Johnson B, Stampfer MJ, Allen J: Plasma concentration of soluble intercellular adhesion molecule-1 and risk of future myocardial infarction in apparently healthy men. Lancet 351:88-92, 1998
5. Ridker PM, Buring JE, Rifai N: Soluble Pselectin and the risk of future cardiovascular events. Circulation 103:491-495, 2001
6. Steiner M, Reinhardt KM, Krammer B, Ernst B, Blann AD: Increased levels of soluble adhesion molecules in type II (non-insulin dependent) diabetes mellitus are independent of glycaemic control. Thromb Haemost 72:979-984, 1994
7. Ferri C, Desideri G, Baldoncini R, Bellini C, De Angelis C, Mazzocchi C, Santucci A: Early activation of vascular endothelium in nonobese, nondiabetic essential hypertensive patients with multiple metabolic abnormalities. Diabetes 47:660-667, 1998
8. Ferri C, Desideri G, Valenti M, Bellini C, Pasin M, Santucci A: Early up-regulation of endothelial adhesion molecules in obese hypertensive men. Hypertension 34:568-573, 1999
9. De Mattia G, Bravi MC, Costanzo A, Laurenti O, Cassone Faldetta M, Armiento A, De Luca O: Effects of insulin on in vitro vascular cell adhesion molecule-1 expression and in vivo soluble VCAM-1 release. Diabetologia 42:1235-1239, 1999
10. Jilma B, Dallinger S, Hergovich N, Eichler HG, Richter V, Wagner OF: Effects of hyperinsulinemia on plasma levels of circulating adhesion molecules. J Clin Endocrinol Metab 85:1748-1751, 2000
11. Marfella R, Esposito K, Giunta R, Coppola G, De Angelis L, Farzati B, Paolisso G, Giugliano D: Circulating adhesion molecules in humans: role of hyperglycemia and hyperinsulinemia. Circulation 101:2247-2251, 2000
12. Blann AD, Lip GYH: Cell adhesion molecules in cardiovascular disease and its risk factors: what can soluble levels tell us? (Editorial) J Clin Endocrinol Metab 85: 1745-1747, 2000
13. Chen N-G, Holmes M, Reaven GM: Relationship between insulin resistance, soluble adhesion molecules, and mononuclear cell binding in healthy volunteers. J Clin Endocrinol Metab 84:3485-3489, 1999
14. Bonora E, Targher G, Alberiche M, Bonadonna RC, Saggiani F, Zenere MB, Uleri S, Muggeo M: Effect of chronic treatment with lacidipine or lisinopril on intracellular partitioning of glucose metabolism in type 2 diabetic patients. J Clin Endocrinol Metab 84:1544-1550, 1999
15. The Joint National Committee: The sixth report of the Joint National Committee on prevention, detection, evaluation and treatment of high blood pressure. Arch Intern Med 157:2413-2446, 1997
16. Lukaski HC, Johnson PE, Bolonchuk WW, Lykken G: Assessment of fat-free mass using bioelectrical impedance measurements of the human body. Am J Clin Nutr 41:810-817, 1985
17. Bonadonna RC, Del Prato S, Bonora E, Gulli G, Solini A, De Fronzo RA: Effects of physiological hyperinsulinemia on the intracellular metabolic partition of plasma glucose. Am J Physiol 265:E943-E953, 1993