Changes in vascular responsiveness to a thromboxane mimetic in endotoxin tolerance

Shock

Volumn 16, Issue 5, 2001, Pages 389-392

  Tempel, George E ^a   Brown, Alan N ^a   Morinelli, Thomas A ^b   Halushka, Perry V ^b   Cook, James A ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Eicosanoids; Endotoxic shock; G proteins; Lipopolysaccharide; Receptor

Indexed keywords

7 (3 (3 HYDROXY 4 (4' IODOPHENOXY) 1 BUTENYL) 7 OXABICYCLO(2.2.1)HEPTAN 2 YL) 5 HEPTENOIC ACID; 7-(3-(3-HYDROXY-4-(4'-IODOPHENOXY)-1-BUTENYL)-7-OXABICYCLO(2.2.1)HEPTAN-2-YL)-5-HEPTENOIC ACID; ENDOTOXIN; FUSED HETEROCYCLIC RINGS; GUANOSINE TRIPHOSPHATASE; INOSITOL; INOSITOL PHOSPHATE; RADIOACTIVE IODINE; UNSATURATED FATTY ACID;

ANIMAL; AORTA; ARTICLE; DRUG EFFECT; IN VITRO STUDY; LONG EVANS RAT; MALE; METABOLISM; MUSCLE CONTRACTION; PATHOPHYSIOLOGY; RAT; SALMONELLA ENTERITIDIS; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; BICYCLO COMPOUNDS, HETEROCYCLIC; ENDOTOXINS; FATTY ACIDS, UNSATURATED; GTP PHOSPHOHYDROLASES; INOSITOL; INOSITOL PHOSPHATES; IODINE RADIOISOTOPES; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, LONG-EVANS; SALMONELLA ENTERITIDIS;

EID: 0035512593     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-200116050-00012     Document Type: Article

References (32)

1. Wolkow PP, Bartus JB, Gryglewski RJ: Pneumotoxicity of lipopolysaccharide in nitric oxide-deficient rats is limited by a thromboxane synthase inhibitor. J Physiol Pharmacol 48:645-653, 1997.
2. Futaki N, Takahashi S, Kitagawa T, Yamakawa Y, Tanaka M, Higuchi S: Selective inhibition of cyclooxygenase-2 by NS-398 in endotoxin shock rats in vivo. Inflamm Res 46:496-502, 1997.
3. Tempel GE, Strong JW, Wise WC, Cook JA, Smith EF III, Halushka PV: The role of eicosanoids in mediating blood flow alterations in endotoxin shock. In Passmore C, Reichard SM, Reynolds DG, Traber DL (eds): Perspectives in Shock Research II. New York: Alan R. Liss, Inc., 1989 pp 33-42.
4. Passmore JC, Jimenez AE: Effectiveness of dual cyclooxygenase and leukotriene blockade with ibuprofen and LY203647 during canine endotoxic shock. Circ Shock 39:21-28, 1993.
5. Gosche JR, Spain DA, Garrison RN, Lüebbe AS, Cryer HG: Differential microvascular response to cyclooxygenase blockade in the rat small intestine during acute bacteremia. Shock 2:408-412, 1994.
6. Suba EA, McKenna TM, Williams TJ: Differential contractile responses of mesenteric and pulmonary artery segments to norepinephrine and phorbol ester in the septic pig. Circ Shock 37:164-168, 1992.
7. Suba EA, McKenna TM, Williams TJ: In vivo and in vitro effects of endotoxin on vascular responsiveness to norepinephrine and signal transduction in the rat. Circ Shock 36:127-133, 1992.
8. 2 alpha (U46619) in the rat. J Pharmacol Exp Ther 253:1171-1176, 1990.
9. Chedid L, Parant M: Microbial Toxins V. New York: Academic Press, 1971, pp 415-456.
10. Greisman SE, Hornick RB, Carozza FA, Woodward TE: The role of endotoxin during typhoid fever and tularemia in man. II. Altered cardiovascular responses to catecholamines. J Clin Invest 43:986-999, 1964.
11. Coffee KA, Halushka PV, Ashton SH, Tempel GE, Wise WC, Cook JA: Endotoxin tolerance is associated with altered GTP-binding protein function. J Appl Physiol 73:1008-1013, 1992.
12. Coffee KA, Halushka PV, Wise WC, Cook JA: Altered responses to modulators of guanine nucleotide binding protein activity in endotoxin tolerance. Biochim Biophys Acta 1035:201-205, 1990.
13. Makhlouf M, Ashton SH, Hildebrandt J, Mehta N, Gettys TW, Haluskha PV, Cook JA: Alteractions in macrophage G proteins are associated with endotoxin tolerance. Biochim Biophys Acta 1312:163-168, 1996.
14. 2 Receptor - Evidence that the affinity state can be altered by G-alpha (13) and G-alpha (Q). J Pharmacol Exp Ther 277:1132-1139, 1996.
15. Shenker A, Goldsmith P, Unson CG, and Spiegel AM: The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family. J Biol Chem 266:9309-9313, 1991.
16. 2 in phospholipid vesicles. Mol Pharmacol 46:808-816, 1994.
17. Vezza R, Habib A, Fitzgerald GA: Differential signaling by the thromboxane receptor isoforms via the novel GTP-binding protein, Gh. J Biol Chem 174: 12774-12779, 1999.
18. 2 stimulates inositol phosphates accumulation in isolated canine mesenteric artery strips. Jpn J Pharmacol 57:349-354, 1991.
19. 2 receptors: distinct subtypes mediate vascular smooth muscle contraction and platelet aggregation. J Pharmacol Exp Ther 258:74-81, 1991.
20. Berridge MJ: Inositol trisphosphate and calcium - two interacting second messengers - presentation of Berridge, Michael, J. The 1996 massry prize laureate, during the award ceremony. Beverly Hills, Calif. Nov 16, 1996. 17(1):1-11, 1997.
21. Becker KP, Garnovskaya M, Gettys T, Halushka PV: Coupling of thromboxane A(2) receptor isoforms to G alpha(13): effects on ligand binding and signaling. Biochim Biophys Acta 1450:288-296, 1999.
22. Wise WC, Cook JA, Halushka PV: Arachidonic acid metabolism in endotoxin tolerance. Adv Shock Res 10:131-142, 1983.
23. 2 mimetic and phenylephrine. J Cardiovasc Pharmacol 17:20-26, 1991.
24. 2 receptor agonist. J Pharmacol Exp Ther 251:557-562, 1989.
25. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the folin phenol reagent. J Biol Chem 193:265-275, 1951.
26. Cassel D, Selinger Z: Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes. Biochim Biophys Acta 452:538-551, 1976.
27. 2 receptor expression in human erythroleukemia cells. Am J Physiol E928-E934, 1993.
28. Milligan G, Green A: Agonist control of G-protein levels. Trends Pharmacol Sci 12:207-209, 1991.
29. Vandewesterlo E, Yang J, Logsdon C, Williams JA: Down-regulation of the G-protein G(Q) alpha and G(11) alpha by transfected human M(3) muscarinic acetylcholine receptors in Chinese hamster ovary cells is independent of receptor down regulation. Biochem J 310:559-563, 1995.
30. Green A, Milligan G, Dobias SB: Gi down-regulation as a mechanism for heterologous desensitization in adipocytes. J Biol Chem 267:3223-3229, 1992.
31. Johnson MD, Wang HY, Ciechanowski D, Friedman E: Reduced G protein function in desensitized rat aorta. J Pharmacol Exp Ther 259:255-259, 1991.
32. Panetta R, Guo Y, Magder S, Greenwood MT: Regulators of G-protein signaling (RGS) 1 and 16 are induced in response to bacterial lipopolysaccharide and stimulate c-fos promoter expression. Biochem Biophys Res Commun 259:550-556, 1999.