Pharmacokinetic interactions of nevirapine and methadone and guidelines for use of nevirapine to treat injection drug users

Clinical Infectious Diseases

Volumn 33, Issue 9, 2001, Pages 1595-1597

  Clarke, Susan M ^a,c   Mulcahy, Fiona M ^a   Tjia, John ^b   Reynolds, Helen E ^b   Gibbons, Sara E ^b   Barry, Michael G ^a   Back, David J ^b  

^a ST JAMES S HOSPITAL   (Ireland)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c BOSTON MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; CYTOCHROME P450 3A4; DIDANOSINE; LAMIVUDINE; METHADONE; NEVIRAPINE; STAVUDINE; ZIDOVUDINE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE CALCULATION; DRUG BLOOD LEVEL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTRAVENOUS DRUG ABUSE; MALE; METHADONE TREATMENT; PRIORITY JOURNAL; WITHDRAWAL SYNDROME;

ADULT; ANALGESICS, OPIOID; ANTI-HIV AGENTS; DRUG ANTAGONISM; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; MALE; METHADONE; MIDDLE AGED; NARCOTIC ANTAGONISTS; NEVIRAPINE; PRACTICE GUIDELINES; REVERSE TRANSCRIPTASE INHIBITORS; SUBSTANCE ABUSE, INTRAVENOUS;

EID: 0035503197     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/322519     Document Type: Article

References (12)

1. The steady-state pharmacokinetics of NVP during once daily and twice daily dosing in HIV-1-infected individuals
2. Nevirapine-induced withdrawal symptoms in HIV patients on methadone maintenance programme: An alert
3. Nevirapine-induced opiate withdrawal among injection drug users with HIV infection receiving methadone
4. The pharmacokinetics of methadone in HIV-positive patients receiving the non-nucleoside reverse transcriptase inhibitor efavirenz
5. Involvement of cytochrome P450 3A4 enzyme in the N-demethylation of methadone in human liver microsomes
6. Rifampicin-induced methadone withdrawal
7. The effects of fluconazole on the clinical pharmacokinetics of methadone
8. Phenytoin-induced methadone withdrawal
9. Nevirapine/didanosine/lamivudine once daily in HIV-1-infected intravenous drug users
10. Methadone withdrawal when starting an antiretroviral regimen including NVP
11. Enzyme induction and inhibition
12. Methadone: One person's maintenance dose is another's poison