Structure-based inhibitor screening: A family of sulfonated dye inhibitors for malaria parasite triosephosphate isomerase

Proteins: Structure, Function and Genetics

Volumn 45, Issue 2, 2001, Pages 136-143

  Joubert, F ^a   Neitz, A W H ^a   Louw, A I ^a  

^a UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

DOCK; Malaria; Plasmodium falciparum; Suramin; Triosephosphate isomerase

Indexed keywords

ANTIMALARIAL AGENT; DYE; ENZYME INHIBITOR; SULFONIC ACID DERIVATIVE; TRIOSEPHOSPHATE ISOMERASE; TRIOSEPHOSPHATE ISOMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CRYSTAL STRUCTURE; DATA BASE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME INHIBITOR INTERACTION; ENZYME MODIFICATION; ENZYME STRUCTURE; INHIBITION KINETICS; MALARIA; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS; SYNTHESIS; THREE DIMENSIONAL IMAGING;

ANIMALS; AZO COMPOUNDS; CLONING, MOLECULAR; COLORING AGENTS; CONGO RED; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TRIOSE-PHOSPHATE ISOMERASE; TRYPAN BLUE;

EID: 0035501756     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.1133     Document Type: Article

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