-
1
-
-
0000899457
-
-
Blakley, R.L. and Benkovics, S.J., eds., Wiley, New York
-
[1] Blakley, R.L. (1984) In: Folates and Pteridines, Vol. 1. Chemistry and Biochemistry of Folates (Blakley, R.L. and Benkovics, S.J., eds.), pp. 191-253. Wiley, New York.
-
(1984)
Folates and Pteridines, Vol. 1. Chemistry and Biochemistry of Folates
, vol.1
, pp. 191-253
-
-
Blakley, R.L.1
-
2
-
-
0000299873
-
Folates in pyrimidine nucleotide biosynthesis
-
Blakley, R.L. and Benkovics, S.J., eds., Wiley, New York
-
[2] Santi, D.V. and Danenberg, P.V. (1984) Folates in pyrimidine nucleotide biosynthesis. In: Folates and Pteridines, Vol. 1, Chemistry and Biochemistry of Folates (Blakley, R.L. and Benkovics, S.J., eds.), pp. 345-398. Wiley, New York.
-
(1984)
Folates and Pteridines, Vol. 1, Chemistry and Biochemistry of Folates
, vol.1
, pp. 345-398
-
-
Santi, D.V.1
Danenberg, P.V.2
-
3
-
-
0026178719
-
Proteolytic and partial sequencing studies of the bifunctional dihydrofolate reductase-thymidylate synthase from Daucus carota
-
[3] Cella, R., Carbonera, D., Orsi, R., Ferri, G. and Ladarola, P. (1991) Proteolytic and partial sequencing studies of the bifunctional dihydrofolate reductase-thymidylate synthase from Daucus carota. Plant Mol. Biol. 16, 975-982.
-
(1991)
Plant Mol. Biol.
, vol.16
, pp. 975-982
-
-
Cella, R.1
Carbonera, D.2
Orsi, R.3
Ferri, G.4
Ladarola, P.5
-
4
-
-
0019179251
-
Dihydrofolate reductase: Thymidylate synthase, a bifunctional polypeptide from Crithidia fasciculata
-
[4] Ferone, R. and Roland, S. (1980) Dihydrofolate reductase: thymidylate synthase, a bifunctional polypeptide from Crithidia fasciculata. Proc. Natl. Acad. Sci. USA. 77, 5802-5806.
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 5802-5806
-
-
Ferone, R.1
Roland, S.2
-
5
-
-
0025317712
-
Bifunctional thymidylate synthase-dihydrofolate reductase in protozoa
-
[5] Ivanetich, K.M. and Santi, D.V. (1990) Bifunctional thymidylate synthase-dihydrofolate reductase in protozoa. FASEB J. 4, 1591-1597.
-
(1990)
FASEB J.
, vol.4
, pp. 1591-1597
-
-
Ivanetich, K.M.1
Santi, D.V.2
-
6
-
-
0027603402
-
The origin of the bifunctional dihydrofolate reductase-thymidylate synthase isogenes of Arabidopsis thaliana
-
[6] Lazar, G., Zhang, H. and Goodman, H.M. (1993) The origin of the bifunctional dihydrofolate reductase-thymidylate synthase isogenes of Arabidopsis thaliana. Plant J. 3, 657-668.
-
(1993)
Plant J.
, vol.3
, pp. 657-668
-
-
Lazar, G.1
Zhang, H.2
Goodman, H.M.3
-
7
-
-
0021287749
-
A bifunctional thymidylate synthetase-dihydrofolate reductase in protozoa
-
[7] Garrett, C.E., Coderre, J.A., Meek, T.D., Garvey, E.P., Claman, D.M., Beverley, S.M. and Santi, D.V. (1984) A bifunctional thymidylate synthetase-dihydrofolate reductase in protozoa. Mol. Biochem. Parasitol. 11, 257-265.
-
(1984)
Mol. Biochem. Parasitol.
, vol.11
, pp. 257-265
-
-
Garrett, C.E.1
Coderre, J.A.2
Meek, T.D.3
Garvey, E.P.4
Claman, D.M.5
Beverley, S.M.6
Santi, D.V.7
-
8
-
-
0003707898
-
-
Bruce-Chwatt,. L.J. ed., WHO, Geneva
-
[8] Bruce-Chwatt, L.J., Black, R.H., Canfield, C.J., Clyde, D.F., Peters, W. and Wernsdorfer, W.H. (1986) In: Chemotherapy of Malaria. Vol. 27 (Bruce-Chwatt,. L.J. ed.), pp. 110-111. WHO, Geneva.
-
(1986)
Chemotherapy of Malaria
, vol.27
, pp. 110-111
-
-
Bruce-Chwatt, L.J.1
Black, R.H.2
Canfield, C.J.3
Clyde, D.F.4
Peters, W.5
Wernsdorfer, W.H.6
-
9
-
-
0000854414
-
Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum
-
[9] Cowman, A.F., Morry, M.J., Biggs, B.A., Cross, G.A.M. and Foote, S.J. (1988) Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum. Proc. Natl. Acad. Sci. USA 85, 9109-9113.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 9109-9113
-
-
Cowman, A.F.1
Morry, M.J.2
Biggs, B.A.3
Cross, G.A.M.4
Foote, S.J.5
-
10
-
-
0025263958
-
Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance
-
[10] Foote, S.J., Galatis, D. and Cowman, A.F. (1990) Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance. Proc. Natl. Acad. Sci. USA 87, 3014-3017.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 3014-3017
-
-
Foote, S.J.1
Galatis, D.2
Cowman, A.F.3
-
11
-
-
0024989797
-
The dihydrofolate reductase-thymidyiate synthase gene in the drug resistance of malaria parasites
-
[11] Hyde, J.E. (1990) The dihydrofolate reductase-thymidyiate synthase gene in the drug resistance of malaria parasites. Pharmacol. Ther. 48, 45-59.
-
(1990)
Pharmacol. Ther.
, vol.48
, pp. 45-59
-
-
Hyde, J.E.1
-
12
-
-
0025252334
-
Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria
-
[12] Peterson, D.S., Milhous, W.K. and Wellems, T.E. (1990) Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria. Proc. Natl. Acad. Sci. USA 87, 3018-3022.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 3018-3022
-
-
Peterson, D.S.1
Milhous, W.K.2
Wellems, T.E.3
-
13
-
-
0025605441
-
Heterologous expression of active thymidylate synthase-dihydrofolate reductase from Plasmodium falciparum
-
[13] Sirawaraporn, W., Sirawaraporn, R., Cowman, A.F., Yuthavong, Y. and Santi, D.V. (1990) Heterologous expression of active thymidylate synthase-dihydrofolate reductase from Plasmodium falciparum. Biochemistry 29, 10779-10785.
-
(1990)
Biochemistry
, vol.29
, pp. 10779-10785
-
-
Sirawaraporn, W.1
Sirawaraporn, R.2
Cowman, A.F.3
Yuthavong, Y.4
Santi, D.V.5
-
14
-
-
0028344368
-
Purification and characterization of dihydrofolate reductase of Plasmodium falciparum expressed by a synthetic gene in Escherichia coli
-
[14] Sano, G.I., Morimatsu, K. and Horii, T. (1994) Purification and characterization of dihydrofolate reductase of Plasmodium falciparum expressed by a synthetic gene in Escherichia coli. Mol. Biochem. Parasitol. 63, 265-273.
-
(1994)
Mol. Biochem. Parasitol.
, vol.63
, pp. 265-273
-
-
Sano, G.I.1
Morimatsu, K.2
Horii, T.3
-
15
-
-
0027445257
-
The dihydrofolate reductase domain of Plasmodium falciparum thymidylate synthase-dihydrofolate reductase: Gene synthesis, expression, and anti-folate resistant mutants
-
[15] Sirawaraporn, W., Prapunwattana, P., Sirawaraporn, R., Yuthavong, Y. and Santi, D.V. (1993) The dihydrofolate reductase domain of Plasmodium falciparum thymidylate synthase-dihydrofolate reductase: gene synthesis, expression, and anti-folate resistant mutants. J. Biol. Chem. 268, 21637-21644.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21637-21644
-
-
Sirawaraporn, W.1
Prapunwattana, P.2
Sirawaraporn, R.3
Yuthavong, Y.4
Santi, D.V.5
-
16
-
-
0024042005
-
Construction of a fol mutant strain of Escherichia coli for use in dihydrofolate reductase mutagenesis experiments
-
[16] Ahrweiler, P.M. and Frieden, C. (1988) Construction of a fol mutant strain of Escherichia coli for use in dihydrofolate reductase mutagenesis experiments. J. Bacteriol. 170, 3301-4.
-
(1988)
J. Bacteriol.
, vol.170
, pp. 3301-3304
-
-
Ahrweiler, P.M.1
Frieden, C.2
-
17
-
-
0026765997
-
Complete replacement set of amino acids at the C-terminus of thymidylate synthase: Quantitative structural-activity relationship of mutants of an enzyme
-
[17] Climie, S.C., Carreras, C.W. and Santi, D.V. (1992) Complete replacement set of amino acids at the C-terminus of thymidylate synthase: quantitative structural-activity relationship of mutants of an enzyme. Biochemistry 31, 6032-6038.
-
(1992)
Biochemistry
, vol.31
, pp. 6032-6038
-
-
Climie, S.C.1
Carreras, C.W.2
Santi, D.V.3
-
18
-
-
0021912893
-
Purification and characterization of the bifunctional thymidylate synthetase-dihydrofolate reductase from methotrexate resistant Leishmania tropica
-
[18] Meek, T.D., Garvey, E.P. and Santi, D.V. (1985) Purification and characterization of the bifunctional thymidylate synthetase-dihydrofolate reductase from methotrexate resistant Leishmania tropica. Biochemistry 24, 678-686.
-
(1985)
Biochemistry
, vol.24
, pp. 678-686
-
-
Meek, T.D.1
Garvey, E.P.2
Santi, D.V.3
-
19
-
-
0001057274
-
Reduction of folate derivatives with dithionite in mercaptoethanol
-
[19] Friedkin, M., Crawford, E.J. and Misra, D. (1962) Reduction of folate derivatives with dithionite in mercaptoethanol. Fed. Proc. Fed. Am. Soc. Exp. Biol. 21, 176.
-
(1962)
Fed. Proc. Fed. Am. Soc. Exp. Biol.
, vol.21
, pp. 176
-
-
Friedkin, M.1
Crawford, E.J.2
Misra, D.3
-
20
-
-
0020307190
-
Secondary a-hydrogen isotope effects on the interaction of 5-fluoro-2′-deoxyuridylate and 5,10-methylenetetrahydrofolate with thymidylate synthetase
-
[20] Bruice, T.W. and Santi, D.V. (1982) Secondary a-hydrogen isotope effects on the interaction of 5-fluoro-2′-deoxyuridylate and 5,10-methylenetetrahydrofolate with thymidylate synthetase. Biochemistry 21, 6703-6709.
-
(1982)
Biochemistry
, vol.21
, pp. 6703-6709
-
-
Bruice, T.W.1
Santi, D.V.2
-
21
-
-
0004136246
-
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
-
[21] Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual 2nd Edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
-
(1989)
Molecular Cloning: A Laboratory Manual 2nd Edn.
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
22
-
-
0019776662
-
Minimization of variation in the response to different proteins of the Coomassie blue G dye-binding assay for protein
-
[22] Read, S.M. and Northcote, D.H. (1981) Minimization of variation in the response to different proteins of the Coomassie blue G dye-binding assay for protein. Anal. Biochem. 116, 53-64.
-
(1981)
Anal. Biochem.
, vol.116
, pp. 53-64
-
-
Read, S.M.1
Northcote, D.H.2
-
23
-
-
0014949207
-
Cleavage of structural proteins during assembly of head of bacteriophage-T4
-
[23] Laemmli, U.K. (1970) Cleavage of structural proteins during assembly of head of bacteriophage-T4. Nature 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
24
-
-
0025835067
-
Automated purification of synthetic oligonucleotides
-
[24] Ivanetich, K.M., Akiyama, J., Santi, D.V. and Reschenberg, M. (1991) Automated purification of synthetic oligonucleotides. BioTechniques 10, 704-707.
-
(1991)
BioTechniques
, vol.10
, pp. 704-707
-
-
Ivanetich, K.M.1
Akiyama, J.2
Santi, D.V.3
Reschenberg, M.4
-
25
-
-
0003144508
-
The electrophoresis of synthetic oligonucleotides
-
Rickwood, D. and Hame, B.D., eds., Oxford University Press: New York
-
[25] Efcavitch, J.W. (1990) The electrophoresis of synthetic oligonucleotides. In: Gel Electrophoresis of Nucleic Acids: a Practical Approach, (Rickwood, D. and Hame, B.D., eds.), pp. 125-149. Oxford University Press: New York.
-
(1990)
Gel Electrophoresis of Nucleic Acids: A Practical Approach
, pp. 125-149
-
-
Efcavitch, J.W.1
-
26
-
-
0025146741
-
Saturation site-directed mutagenesis of thymidylate synthase
-
[26] Climie, S.C., Ruiz-Perez, L., Gonzalez-Pacanowska, D., Prapunvvattana, P., Cho, S.W., Stroud, R.M. and Santi, D.V. (1990) Saturation site-directed mutagenesis of thymidylate synthase. J. Biol. Chem. 265, 18 776-18 779.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 18776-18779
-
-
Climie, S.C.1
Ruiz-Perez, L.2
Gonzalez-Pacanowska, D.3
Prapunvvattana, P.4
Cho, S.W.5
Stroud, R.M.6
Santi, D.V.7
-
27
-
-
0026523115
-
A PCR-mediated gene synthesis strategy involving the assembly of oligonucleotides representing only one of the strands
-
[27] Jayaraman, K. and Puccini, C.J. (1992) A PCR-mediated gene synthesis strategy involving the assembly of oligonucleotides representing only one of the strands. BioTechniques 12, 392-398.
-
(1992)
Biotechniques
, vol.12
, pp. 392-398
-
-
Jayaraman, K.1
Puccini, C.J.2
-
28
-
-
0001651897
-
Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene
-
[28] Bzik, D.J., Li, W.-B., Horii, T. and Inselburg, J. (1987) Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene. Proc. Natl. Acad. Sci. USA 84, 8360-8364.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 8360-8364
-
-
Bzik, D.J.1
Li, W.-B.2
Horii, T.3
Inselburg, J.4
-
29
-
-
0028403267
-
Structure of and kinetic channelling in bifunctional dihydrofolate reductase-thymidylate synthase
-
[29] Knighton, D.R., Kan, C.-C., Howland, E., Janson, C.A., Hostomska, Z., Welsh, K.M. and Matthews, D.A. (1994) Structure of and kinetic channelling in bifunctional dihydrofolate reductase-thymidylate synthase. Nature Struct. Biol. 1, 186-194.
-
(1994)
Nature Struct. Biol.
, vol.1
, pp. 186-194
-
-
Knighton, D.R.1
Kan, C.-C.2
Howland, E.3
Janson, C.A.4
Hostomska, Z.5
Welsh, K.M.6
Matthews, D.A.7
-
30
-
-
0023176096
-
Kinetic and molecular properties of the dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant clones of the human malaria parasite Plasmodium falciparum
-
[30] Chen, G.X., Mueller, C., Wendlinger, M. and Zolg, J.W. (1987) Kinetic and molecular properties of the dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant clones of the human malaria parasite Plasmodium falciparum. Mol. Pharmacol. 31, 430-437.
-
(1987)
Mol. Pharmacol.
, vol.31
, pp. 430-437
-
-
Chen, G.X.1
Mueller, C.2
Wendlinger, M.3
Zolg, J.W.4
|