Tea: A rich brew of anti-cancer magic bullets?

Drug Discovery Today

Volumn 6, Issue 21, 2001, Pages 1079-1080

  Senior, Kathryn ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; EPIGALLOCATECHIN GALLATE; NONSTEROID ANTIINFLAMMATORY AGENT; RESVERATROL; STILBENE DERIVATIVE; THEAFLAVIN;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CELL KILLING; CHEMOPROPHYLAXIS; COLON CANCER; DRUG EFFECT; DRUG MECHANISM; DRUG SYNTHESIS; ENZYME INHIBITION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE TARGETING; GRAPE; HUMAN; INFLAMMATION; NONHUMAN; PEANUT; PLANT LEAF; SHORT SURVEY; TEA;

EID: 0035500079     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(01)02022-0     Document Type: Short Survey

References (7)

1. Effects of polyphenolic compounds in black tea and grape on the expression of specific genes in normal and cancerous human cell
2. Differential effects of the theaflavin monogallates on cell growth, apoptosis and COX-2 gene expression in cancerous versus normal cells
3. Upregulation of cyclooxygenase-2 gene expression in human colorectal adenomas and adenocarcinomas
4. Suppression of intestinal polyposis in APC delta716 knockout mice by inhibition of cyclooxygenase-2 (COX-2)
5. Theaflavins in black tea and catechins in green tea are equally effective antioxidants
6. Reseveratrol analog, 3,4,5,4′-tetrahydroxystilbene, differentially induces pro-apoptotic p53/Bax gene expression and inhibits the growth of transformed cells but not their normal counterparts