tRNAs in the spotlight during protein biosynthesis

Trends in Biochemical Sciences

Volumn 26, Issue 11, 2001, Pages 653-656

  Brosius, Jürgen ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MESSENGER RNA; RIBOSOME RNA; RNA; TRANSFER RNA;

CELL ORGANELLE; CRYSTAL STRUCTURE; EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REVIEW; RIBOSOME; RNA TRANSLATION;

AMINO ACID SEQUENCE; EVOLUTION, MOLECULAR; MODELS, CHEMICAL; MODELS, MOLECULAR; PEPTIDE BIOSYNTHESIS; PROKARYOTIC CELLS; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; RIBOSOMAL PROTEINS; RIBOSOMES; RNA, MESSENGER; RNA, RIBOSOMAL; RNA, TRANSFER;

EID: 0035499046     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(01)01972-7     Document Type: Review

References (38)

1. Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena
2. The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
3. Molecular mechanics of translation: A reciprocating ratchet mechanism
4. Just So Stories and Rube Goldberg machines: Speculations on the origin of the protein synthetic machinery
5. Structure and topography of ribosomal RNA
6. Unusual resistance of peptidyl transferase to protein extraction procedures
7. The complete atomic structure of the large ribosomal subunit at 2.4 Å resolution
8. The structural basis of ribosome activity in peptide bond synthesis
9. Ribosomes. Drugs and the RNA world
10. An RNA replisome as the ancestor of the ribosome
11. Amino acids as RNA ligands: A direct-RNA-template theory for the code's origin
12. Peptide-specific ribosomes, genomic tags, and the origin of the genetic code
13. Structure and function of genetic elements
14. tRNA-like structures tag the 3′ ends of genomic RNA molecules for replication: Implications for the origin of protein synthesis
15. Ribozyme-catalyzed tRNA aminoacylation
16. An in vitro evolved precursor tRNA with aminoacylation activity
17. Exiting an RNA world
18. Oligonucleotide-directed peptide synthesis in a ribosome- and ribozyme-free system
19. A single adenosine with a neutral pKa in the ribosomal peptidyl transferase center
20. Structural biology. The ribosome is a ribozyme
21. Mechanism of ribosomal peptide bond formation
22. Mechanism of ribosomal peptide bond formation
23. Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide
24. Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit
25. A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition
26. Mechanism of ribosomal peptide bond formation
27. Transfer-RNA, an early gene?
28. Transmutation of tRNA over time
29. The Ssr-SmpB system for protein tagging, directed degradation and ribosome rescue
30. Ala recognizes transfer-messenger RNA with specificity; a functional complex prior to entering the ribosome?
31. 23S rRNA similarity from selection for peptidyl transferase mimicry
32. Peptide bond formation by in vitro selected ribozymes
33. Peptidyl-transferase ribozymes: Trans reactions, structural characterization and ribosomal RNA-like features
34. The evolution of cellular tape reading processes and macromolecular complexity
35. Translation: In retrospect and prospect
36. Crystal structure of the ribosome at 5.5 Å resolution
37. A ratchet-like inter-subunit reorganization of the ribosome during translocation
38. Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle