Studies of molecular structure parameters of 20-piperidin-2-yl-5α-pregnan-3β,20-diol and its N-methyl derivative: Two inhibitors of Δ24(24) sterol methyl transferase and Δ24(24′) sterol methyl reductase of Trypanosoma cruzi

Acta Crystallographica Section B: Structural Science

Volumn 57, Issue 5, 2001, Pages 714-721

  Atencio, Reinaldo ^a   Visbal, Gonzalo ^a   Pekerar, Sara ^a   Papale, Jham ^a   Urbina, Julio A ^a  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

Author keywords

[No Author keywords available]

Indexed keywords

20 N METHYLPIPERIDIN 2 YL 5 PREGNAN 3,20 DIOL; 20 PIPERIDIN 2 YL 5 PREGNAN 3,20 DIOL; 20-N-METHYLPIPERIDIN-2-YL-5-PREGNAN-3,20-DIOL; 20-PIPERIDIN-2-YL-5-PREGNAN-3,20-DIOL; ANTITRYPANOSOMAL AGENT; DELTA 24 STEROL METHYLTRANSFERASE; DELTA 24-STEROL METHYLTRANSFERASE; DRUG DERIVATIVE; ENZYME INHIBITOR; METHYLTRANSFERASE; PREGNANEDIOL;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; ENZYMOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSIOLOGY; STEREOISOMERISM; SYNTHESIS; TRYPANOSOMA CRUZI; X RAY CRYSTALLOGRAPHY;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; ENZYME INHIBITORS; MAGNETIC RESONANCE SPECTROSCOPY; METHYLTRANSFERASES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PREGNANEDIOL; STEREOISOMERISM; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

EID: 0035489033     PISSN: 01087681     EISSN: None     Source Type: Journal    
DOI: 10.1107/S0108768101013234     Document Type: Article

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