Efficient ex vivo generation of human dendritic cells from mobilized CD34+ peripheral blood progenitors

International Journal of Hematology

Volumn 74, Issue 3, 2001, Pages 287-296

  Ohishi, Kohshi ^a   Katayama, Naoyuki ^a   Mitani, Hidetsugu ^a   Araki, Hiroto ^a   Masuya, Masahiro ^a   Suzuki, Hirohito ^a   Hoshino, Natsuki ^a   Miyashita, Hiroyuki ^a   Nishii, Kazuhiro ^a   Kageyama, Shin Ichi ^a   Minami, Nobuyuki ^b   Shiku, Hiroshi ^a  

^a MIE UNIVERSITY   (Japan)

^b MIE UNIVERSITY HOSPITAL   (Japan)

Author keywords

Dendritic cells; G CSF; IL 4; Mobilized CD34+ hematopoietic progenitors; Thrombopoietin

Indexed keywords

CD1 ANTIGEN; CD14 ANTIGEN; CD34 ANTIGEN; GROWTH PROMOTOR; T6 ANTIGEN;

ARTICLE; BLOOD; BLOOD DISEASE; CELL CULTURE; CELL DIFFERENTIATION; CHEMISTRY; CULTURE MEDIUM; CYTOLOGY; DENDRITIC CELL; DRUG EFFECT; DRUG INTERACTION; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOLOGY; IMMUNOPHENOTYPING; METHODOLOGY; MIXED LYMPHOCYTE CULTURE; STEM CELL MOBILIZATION;

ANTIGENS, CD1; ANTIGENS, CD14; ANTIGENS, CD34; CELL CULTURE; CELL DIFFERENTIATION; CULTURE MEDIA; DENDRITIC CELLS; DRUG INTERACTIONS; GROWTH SUBSTANCES; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELLS; HUMAN; IMMUNOPHENOTYPING; LYMPHOCYTE CULTURE TEST, MIXED; SUPPORT, NON-U.S. GOV'T;

EID: 0035488651     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02982063     Document Type: Article

References (25)

1. Steinman RM. The dendritic cell system and its role in immunogenicity. Annu Rev Immunol. 1991;9:271-296.
2. Caux C, Liu Y-J, Banchereau J. Recent advances in the study of dendritic cells and follicular dendritic cells. Immunol Today. 1995;16:2-5.
3. Hart DNJ. Dendritic cells: unique leukocyte populations which control the primary immune response. Blood. 1997;90:3245-3287.
4. Banchereau J, Briere F, Caux C, et al. Immunobiology of dendritic cells. Annu Rev Immunol. 2000;18:767-811.
5. Grabbe S, Beissert S, Schwart T, Granstein R. Dendritic cells as initiators of tumor immune responses: A possible strategy for tumor immunotherapy? Immunol Today. 1995;16:117-121.
6. Frelinger JG, Hood L, Hill S, Frelinger JA. Mouse epidermal la molecules have a bone marrow origin. Nature. 1979:282:321-323.
7. Katz SI, Tamaki K, Sachs DH. Epidermal Langerhans cells are derived from cells originating in bone marrow. Nature. 1979;282: 324-326.
8. Inaba K, Inaba M, Deguchi M, et al. Granulocytes, macrophages, and dendritic cells arise from a common major histocompatibility complex class II-negative progenitor in mouse bone marrow. Proc Natl Acad Sci U S A. 1993;90:3038-3042.
9. Ardavin C, Wu L, Li C-L, Shortman K. Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population. Nature. 1993:362:761-763.
10. Volc-Platzer B, Stingl G, Wolff K, Hinterberg W, Schnedl W. Cytogenetic identification of allogeneic epidermal Langerhans cells in a bone-marrow-graft recipient. N Engl J Med. 1984-310:1123-1124.
11. Reid CDL, Fryer PR, Clifford C, Kirk A, Tikerpae J, Knight SC. Identification of hematopoietic progenitors of macrophages and dendritic Langerhans cells (DL-CFU) in human bone marrow and peripheral blood. Blood. 1990;76:1139-1149.
12. + progenitors in human bone marrow. J Immunol. 1992;149:2681-2688.
13. + bone marrow precursors cultured with c-kit ligand, granulocytemacrophage colony-stimulating factor, and TNF-α. J Immunol. 1995;154:5851-5861.
14. Galy A, Travis M, Cen D, Chen B. Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor subset. Immunity. 1995;3:459-473.
15. Caux C, Dezutter-Dambuyant C, Schmitt D, Banchereau J. GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells. Nature. 1992;360:258-261.
16. Santiago-Schwarz F, Belilos E, Diamond B, Carsons SE. TNF in combination of GM-CSF enhances the differentiation of neonatal cord blood stem cells into dendritic cells and macrophages. J Leukoc Biol. 1992;52:274-281.
17. + hematopoietic progenitor cells of the bone marrow and peripheral blood. Cancer Res. 1995;55:1099-1104.
18. Mackensen A, Herbst B, Köhler G, et al. Delineation of the dendritic cell lineage by generating large numbers of Birbeck granule-positive Langerhans cells from human peripheral blood progenitor cells in vitro. Blood. 1995;86:2699-2707.
19. + blood progenitors for anticancer therapy. Exp Hematol. 1995;23:1463-1471.
20. + hematopoietic progenitor cells. Blood. 1996;87:1292-1302.
21. + peripheral blood progenitor cell and monocyte derived dendritic cells: a comparative analysis. Br J Haematol. 1997;99:490-499.
22. + bone marrow progenitors that are expanded by c-kit-ligand and yield pure dendritic cell colonies in the presence of granulocyte/macrophage colony-stimulating factor and tumor necrosis factor α. J Exp Med. 1995:182:1111-1120.
23. + hematopoietic precursor cells. Blood. 1996;87:535-544.
24. + hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNFα. J Exp Med. 1996;184:695-706.
25. Strobl H, Bello-Fernandez C, Reidl E, et al. flt3 ligand in cooperation with transforming growth factor-β1 potentiates in vitro development of Langerhans-type dendritic cells and allows single-cell dendritic cell cluster formation under serum-free conditions. Blood. 1997;90:1425-1434.