Exon structure conservation despite low sequence similarity: A relic of dramatic events in evolution?

EMBO Journal

Volumn 20, Issue 19, 2001, Pages 5354-5360

  Betts, Matthew J ^a,b   Guigó, Roderic ^c   Agarwal, Pankaj ^d   Russell, Robert B ^a,e  

^a GLAXOSMITHKLINE   (United Kingdom)

^b DECODE GENETICS   (Iceland)

^c INST MUNIC D INVESTIGACIO MEDICA   (Spain)

^d GLAXOSMITHKLINE   (United States)

^e EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Evolution; Exon; Immune system; Intron; Protein structure

Indexed keywords

ALBUMIN; CELL NUCLEUS RECEPTOR; CHEMOKINE; CYSTATIN; CYTOKINE; GRANULIN; HEMOPEXIN; LYSOZYME; M PROTEIN; MEPRIN; PHOSPHOLIPASE A2; PROTEINASE; TRYPSIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; EXON; GENE STRUCTURE; IMMUNE RESPONSE; INTRON; MOLECULAR EVOLUTION; NEMATODE; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VERTEBRATE;

AMINO ACID SEQUENCE; CYTOKINES; EVOLUTION, MOLECULAR; EXONS; GENES; GTPASE-ACTIVATING PROTEINS; INTRONS; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 0035477813     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.19.5354     Document Type: Article

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