Preoperative serum levels of the carcinoembrionary antigen (CEA) and prognosis in colorectal cancer;Niveles séricos preoperatorios del CEA y pronóstico en el cáncer colorrectal

Revista Espanola de Medicina Nuclear

Volumn 20, Issue 5, 2001, Pages 358-364

  Allende Monclús, Ma Teresa ^a   Garcia Muniz J L ^a   Vizoso, F ^b   Del Casar, J M ^b   Raigoso, P ^a   Llana, B ^a   Serra, C ^c   Zeidan N ^a   Garcia Moran M ^a   Roiz, C ^a  

^a HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

^b HOSPITAL DE JOVE   (Spain)

^c HOSPITAL VIRGEN DE LOS LIRIOS   (Spain)

Author keywords

Carcinoembryonic antigen; Colorectal cancer; Prognosis; Tumoral markers

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; TUMOR MARKER; TUMOR PROTEIN;

ADULT; AGED; ANTIGEN DETECTION; ARTICLE; BLOOD LEVEL; CANCER SURVIVAL; COLORECTAL CARCINOMA; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; OVERALL SURVIVAL; PREDICTION; PREOPERATIVE EVALUATION; PROGNOSIS; UNIVARIATE ANALYSIS; ADENOCARCINOMA; BLOOD; CANCER STAGING; COLORECTAL TUMOR; COMPARATIVE STUDY; DISEASE FREE SURVIVAL; EVALUATION; LIFE TABLE; MIDDLE AGED; MORTALITY; PATHOLOGY; PREOPERATIVE CARE; PROSPECTIVE STUDY; SPAIN; SURVIVAL;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; CARCINOEMBRYONIC ANTIGEN; COLORECTAL NEOPLASMS; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; LIFE TABLES; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM PROTEINS; NEOPLASM STAGING; PREOPERATIVE CARE; PROGNOSIS; PROSPECTIVE STUDIES; SPAIN; SURVIVAL ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 0035432956     PISSN: 02126982     EISSN: 1578200X     Source Type: Journal    
DOI: 10.1016/s0212-6982(01)71974-x     Document Type: Article

References (28)

1. Gold P. Specific carcinoembryonic antigens of the human digestive system. J Exp Med 1965;122(3):467-81.
2. Cutait R, Alves VA, Lopes LC, Cutait T, Borges JL, Singer J, et al. Restaging of colorectal cancer based on the identification of lymph node micrometastases though immunoperoxidase staining of CEA and cytokeratins. Dis Colon Rectum 1991;34(10):917-20.
3. American Society of Clinical Oncology (ASCO). Clinical practice guilines for the use of tumor markers in breast and colorectal cancer. Adopted on May 17, 1996 by the American Society of Clinical Oncology. J Clin Oncol 1996;14(10):2843-77.
4. Schwartz MK. Current status of tumor markers. Scand J Clin Lab Invest 1995;221(1 Supl 2):5-12.
5. Bleiberg H. Continuing the fight against advanced colorectal cancer: new and future treatment options. Anticancer Drugs 1998;9(1):18-28. Review.
6. Labianca R, Pessi MA, Zamparelli G. Treatment of colorectal cancer. Current guidelines and future prospects for drug therapy. Drugs 1997;53(4):593-607. Review.
7. lo Gerfo P, Herter FP. Carcinoembryonic antigen and prognosis in patients with colon cancer. Ann Surg 1975;181(1):81-4.
8. Wanebo HJ, Rao B, Pinsky CM, Hoffman RG, Stearns M, Schwartz MK, et al. Pre-operative carcinoembryonic antigen level as a prognostic indicator in colorectal cancer. N Engl J Med 1978;299(9):448-51.
9. Wolmark N, Fisher B, Wieand HS, Henry RS. The prognostic significance of preoperative carcinoembryonic antigen levels in colorectal cancer. Ann Surg 1984;199(4):375-81.
10. Harrison LE, Guillen JG, Paty Ph, Cohen AM. Preoperative carcinoembryonic antigen predicts outcomes in node-negative colon cancer patients: a multivariate analysis of 572 patients. J Am Coll Surg 1997;185(1):55-9.
11. González A, Vizoso F, Ais G, García Muñiz JL, Rodríguez JC, Ruibal A, et al. Concentraciones séricas preoperatorias de TAG-72 y CEA como indicadores pronósticos en el carcinoma colorrectal resecable. Cir Esp 1997;62(6):452-8.
12. Andicoechea A, Vizoso F, Alexandre E, Cuesta E, Díez MC, Riera L, et al. Preoperative carbohydrate antigen 195 (CA 195) and CEA serum levels as prognostic factors in patients with colorectal cancer. Int J Biol Markers 1998;13(3):158-64.
13. Park YJ, Park KJ, Park JG, Lee KU, Choe KJ, Kim JP. Prognostic factors in 2,230 korean colorectal cancer patients: analysis of consecutively operated cases. World J Surg 1999;23(7):721-6.
14. Filella X, Molina R, Piqué JM, Grau JJ, García-Valdecasas JC, Biete A, et al. CEA as a prognostic factor in colorectal cancer. Anticancer Res 1994;14(2B):705-8.
15. Wang JY, Tang R, Chiang JM. Value of carcinoembryonic antigen in the managenent of colorectal cancer. Dis Colon Rectum 1994;37(3):272-7. Review.
16. Díez M, Cerdán FJ, Pollan M, Maestro ML, Ortega MD, Martínez S, et al. Prognostic significance of preoperative serum CA 19.9 assay in patients with colorectal carcinoma. Anticancer Res 1994;14(6B):2819-25.
17. Lindmark G, Bergstrom R, Pahlman L, Glimelius B. The association of preoperative serum tumor markers with Dukes' stage and survival in colorectal cancer. Br J Cancer 1995;71(5):1090-4.
18. Chapman MAS, Buckley D, Hensos DB, Armitage NC. Preoperative carcinoembryonic antigen is related to tumor stage and long-term survival in colorectal cancer. Br J Cancer 1998;78(10):1346-9.
19. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-481.
20. Mantel N, Myers M. Problems of convergence of maximum likehood iterative procedures in multiparameter situations. J Am Statis Assoc 1971;66:484-491.
21. Cox DR. Regression models and life tables. J R Statist Soc B 1972;34:187-220.
22. Dixon WJ, Brown MB, Engelman L, Frane JW, Hill MA, Jennrich RI, et al. BMDP statistical software. Berkeley: University of California Press; 1985.
23. Goslin R, Steele G, MacIntyre J, Mayer R, Sugarbacker P, Cleghorn K, et al. The use of preoperative plasma CEA levels for the stratification of patients after curative resection of colorectal cancers. An Surg 1980;192(6):747-51.
24. Wagner HE, Toth CA, Steele GD, Thomas P. Invasive and metastasic potential of human colorectal cancer cell lines: relationship to cellular differentiation and carcinoembryonic antigen production. Clin Exp Metastasis 1992;10(1):25-31.
25. Tibbetts LM, Doremus CM, Tzanakakis GN, Vezerdis MP. Liver metastases with 10 human colon carcinoma cell lines in nude mice and association with carcinoembryonic antigen production. Cancer 1993;71(2):315-21.
26. Hostetter RB, Augustus LB, Mankarious R, Chi K, Fan D, Toth CA, et al. Carcinoembryonic antigen as a selective enhacer of colorectal cancer metastases. J Natl Cancer Inst 1990;82(5):380-5.
27. Gangopadhyay A, Bajenova O, Kelly TM, Thomas P. Carcinoembryonic antigen induces cytokine expression in Kupffer cells: implications for hepatic metastasis from colorectal cancer. Cancer Res 1996;56(20):4805-10.
28. Kim JC, Han MS, Lee HK, Kim WS, Park SK, Park KC, et al. Distribution of carcinoembryonic antigen and biologic beha-