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Volumn 9, Issue 1, 1998, Pages 18-28

Continuing the fight against advanced colorectal cancer: New and future treatment options

Author keywords

Colorectal cancer; Fluorouracil; Irinotecan; Oxaliplatin; Treatment outcome; ZD1694

Indexed keywords

2 [5 [[(1,2 DIHYDRO 3 METHYL 1 OXOBENZO[F]QUINAZOLIN 9 YL)METHYL]AMINO] 1 OXO 2 ISOINDOLINYL]GLUTARIC ACID; 5 ETHYNYLURACIL; 7 ETHYL 10 HYDROXYCAMPTOTHECIN; BATIMASTAT; BISNAFIDE MESYLATE; CARCINOEMBRYONIC ANTIBODY; DNA TOPOISOMERASE INHIBITOR; DROLOXIFENE; EDRECOLOMAB; FLUOROURACIL; GASTRIN 17; IMMUNOMODULATING AGENT; IMMUNOSTIMULATING AGENT; IRINOTECAN; METESIND GLUCURONATE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY MN 14; NOLATREXED; OXALIPLATIN; PEMETREXED; PLATINUM DERIVATIVE; RA 700; RALTITREXED; ROQUINIMEX; THROMBOCYTE FACTOR 4; THYMIDYLATE SYNTHASE INHIBITOR; TOPOTECAN; UNCLASSIFIED DRUG; XOMAZYME;

EID: 0031912341     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199801000-00002     Document Type: Review
Times cited : (13)

References (83)
  • 4
    • 0028274802 scopus 로고
    • Folinic acid 5-fluorouracil as adjuvant therapy in colon cancer
    • Francini G, Petrioli R, Lorenzini L, et al. Folinic acid 5-fluorouracil as adjuvant therapy in colon cancer. Gastroenterology 1994; 106: 899-906.
    • (1994) Gastroenterology , vol.106 , pp. 899-906
    • Francini, G.1    Petrioli, R.2    Lorenzini, L.3
  • 5
    • 0028956045 scopus 로고
    • Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: A final report
    • Moertel CG, Fleming TR, MacDonald JS, et al. Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report. Ann Intern Med 1995; 122: 321-6.
    • (1995) Ann Intern Med , vol.122 , pp. 321-326
    • Moertel, C.G.1    Fleming, T.R.2    MacDonald, J.S.3
  • 6
    • 0029644482 scopus 로고
    • Efficacy of adjuvant fluorouracil and folinic acid in colon cancer
    • International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) Investigators. Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. Lancet 1995; 345: 939-44.
    • (1995) Lancet , vol.345 , pp. 939-944
  • 7
    • 0028158914 scopus 로고
    • Local recurrence of colorectal cancer: The problem, the mechanisms, management and adjuvant therapy
    • Abulafi AM, Williams NS. Local recurrence of colorectal cancer: the problem, the mechanisms, management and adjuvant therapy. Br J Surg 1994; 81: 7-19.
    • (1994) Br J Surg , vol.81 , pp. 7-19
    • Abulafi, A.M.1    Williams, N.S.2
  • 8
    • 0022592646 scopus 로고
    • Local recurrence of colorectal cancer effect of early detection and aggressive surgery
    • Schiessel R, Wunderlich M, Herbst F. Local recurrence of colorectal cancer effect of early detection and aggressive surgery. Br J Surg 1986; 73: 342-4.
    • (1986) Br J Surg , vol.73 , pp. 342-344
    • Schiessel, R.1    Wunderlich, M.2    Herbst, F.3
  • 10
    • 0029019493 scopus 로고
    • Therapeutic modalities and prognostic factors for primary and secondary liver tumours
    • Lehnert T, Otto G, Herfarth C. Therapeutic modalities and prognostic factors for primary and secondary liver tumours. World J Surg 1995; 19: 252-63.
    • (1995) World J Surg , vol.19 , pp. 252-263
    • Lehnert, T.1    Otto, G.2    Herfarth, C.3
  • 12
    • 0026762968 scopus 로고
    • Expectancy or primary chemotherapy in patients with advanced asymptomatic colorectal cancer: A randomized trial
    • Nordic Gastrointestinal Tumor Adjuvant Therapy Group. Expectancy or primary chemotherapy in patients with advanced asymptomatic colorectal cancer: a randomized trial. J Clin Oncol 1992; 10: 904-11.
    • (1992) J Clin Oncol , vol.10 , pp. 904-911
  • 13
    • 0027461840 scopus 로고
    • Randomised comparison of combination chemotherapy plus supportive care with supportive care alone in patients with metastatic colorectal cancer
    • Scheithauer W, Rosen H, Kornek GV, Sebesta C, Depisch D. Randomised comparison of combination chemotherapy plus supportive care with supportive care alone in patients with metastatic colorectal cancer. Br Med J 1993; 306: 752-5.
    • (1993) Br Med J , vol.306 , pp. 752-755
    • Scheithauer, W.1    Rosen, H.2    Kornek, G.V.3    Sebesta, C.4    Depisch, D.5
  • 14
    • 0028945766 scopus 로고
    • Cost-effectiveness of palliative chemotherapy in advanced gastrointestinal cancer
    • Glimelius B, Hoffman K, Graf W, et al. Cost-effectiveness of palliative chemotherapy in advanced gastrointestinal cancer. Ann Oncol 1995; 6: 267-74.
    • (1995) Ann Oncol , vol.6 , pp. 267-274
    • Glimelius, B.1    Hoffman, K.2    Graf, W.3
  • 15
    • 0026721532 scopus 로고
    • Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate
    • Advanced Colorectal Cancer Meta-Analysis Project. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. J Clin Oncol 1992; 10: 896-903.
    • (1992) J Clin Oncol , vol.10 , pp. 896-903
  • 16
    • 0028351657 scopus 로고
    • Chemotherapy for colorectal cancer
    • Moertel CG. Chemotherapy for colorectal cancer. N Engl J Med 1994; 330: 1136-42.
    • (1994) N Engl J Med , vol.330 , pp. 1136-1142
    • Moertel, C.G.1
  • 17
    • 0024347268 scopus 로고
    • Biochemical modulation of fluorouracil: Evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma
    • Poon MA, O'Connell MJ, Moertel CG, et al. Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma. J Clin Oncol 1989; 7: 1407-17.
    • (1989) J Clin Oncol , vol.7 , pp. 1407-1417
    • Poon, M.A.1    O'Connell, M.J.2    Moertel, C.G.3
  • 18
    • 0028219974 scopus 로고
    • Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer
    • Advanced Colorectal Cancer Meta-Analysis Project. Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer. J Clin Oncol 1994; 12: 960-9.
    • (1994) J Clin Oncol , vol.12 , pp. 960-969
  • 19
    • 0016768026 scopus 로고
    • Comparison of continuously infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma
    • Seifert P, Baker LH, Reed ML, Vaitkevicius VK. Comparison of continuously infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma. Cancer 1975; 36: 123-8.
    • (1975) Cancer , vol.36 , pp. 123-128
    • Seifert, P.1    Baker, L.H.2    Reed, M.L.3    Vaitkevicius, V.K.4
  • 20
    • 0024539308 scopus 로고
    • A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: A Mid-Atlantic Oncology Program study
    • Lokich JJ, Ahlgren JD, Gullo JJ, Philips JA, Fryer JG. A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program study. J Clin Oncol 1989; 7: 425-32.
    • (1989) J Clin Oncol , vol.7 , pp. 425-432
    • Lokich, J.J.1    Ahlgren, J.D.2    Gullo, J.J.3    Philips, J.A.4    Fryer, J.G.5
  • 21
    • 0023790494 scopus 로고
    • Cisplatin and 5-fluorouracil versus 5-fluorouracil alone in advanced colorectal cancer: A randomized study
    • Labianca R, Pancera G, Cesana B, Clerici M, Montinari F, Luporini G. Cisplatin and 5-fluorouracil versus 5-fluorouracil alone in advanced colorectal cancer: a randomized study. Eur J Clin Oncol 1988; 24: 1579-81.
    • (1988) Eur J Clin Oncol , vol.24 , pp. 1579-1581
    • Labianca, R.1    Pancera, G.2    Cesana, B.3    Clerici, M.4    Montinari, F.5    Luporini, G.6
  • 22
    • 0025615898 scopus 로고
    • Randomized phase II study of a combination of cisplatin (DDP), 5-fluorouracil (5-FU) and allopurinol (HHP) versus 5-fluorouracil in colorectal cancer. An EORTC Gastrointestinal Tract Cancer Cooperative Group Study
    • Bleiberg H, Vanderlinden B, Buyse M, et al. Randomized phase II study of a combination of cisplatin (DDP), 5-fluorouracil (5-FU) and allopurinol (HHP) versus 5-fluorouracil in colorectal cancer. An EORTC Gastrointestinal Tract Cancer Cooperative Group Study. Cancer Invest 1990; 8: 471-5.
    • (1990) Cancer Invest , vol.8 , pp. 471-475
    • Bleiberg, H.1    Vanderlinden, B.2    Buyse, M.3
  • 23
    • 0016440838 scopus 로고
    • Brief communication. Therapy of advanced colorectal cancer with a combination of 5-fluorouracil, methyl-1,3-cis(2-chloroethyl)-1-nitrosourea and vincristine
    • Moertel CG, Schutt AJ, Hahn RG, Reitemeier RJ. Brief communication. Therapy of advanced colorectal cancer with a combination of 5-fluorouracil, methyl-1,3-cis(2-chloroethyl)-1-nitrosourea and vincristine. J Natl Cancer Inst 1975; 54: 69-71.
    • (1975) J Natl Cancer Inst , vol.54 , pp. 69-71
    • Moertel, C.G.1    Schutt, A.J.2    Hahn, R.G.3    Reitemeier, R.J.4
  • 25
    • 0018413696 scopus 로고
    • A randomized study of two different schedules of methyl CCNU, 5-FU and vincristine for metastatic colorectal carcinoma
    • Kemeny N, Yagoda A, Braun D Jr, Golbey R. A randomized study of two different schedules of methyl CCNU, 5-FU and vincristine for metastatic colorectal carcinoma. Cancer 1979; 43: 78-82.
    • (1979) Cancer , vol.43 , pp. 78-82
    • Kemeny, N.1    Yagoda, A.2    Braun Jr., D.3    Golbey, R.4
  • 26
    • 0024425297 scopus 로고
    • A randomized trial of continuous intravenous versus hepatic intraarterial floxuridine in patients with colorectal cancer metastatic to the liver: The Northern California Oncology Group trial
    • Hohn DC, Stagg RJ, Freidman MA, et al. A randomized trial of continuous intravenous versus hepatic intraarterial floxuridine in patients with colorectal cancer metastatic to the liver: The Northern California Oncology Group trial. J Clin Oncol 1989; 7: 1646-54.
    • (1989) J Clin Oncol , vol.7 , pp. 1646-1654
    • Hohn, D.C.1    Stagg, R.J.2    Freidman, M.A.3
  • 27
    • 0025078610 scopus 로고
    • Intra-arterial floxuridine vs systemic fluorouracil for hepatic metastases from colorectal cancer
    • Martin JK, O'Connell MJ, Wienand HS, et al. Intra-arterial floxuridine vs systemic fluorouracil for hepatic metastases from colorectal cancer. Arch Surg 1990; 125: 1022-7.
    • (1990) Arch Surg , vol.125 , pp. 1022-1027
    • Martin, J.K.1    O'Connell, M.J.2    Wienand, H.S.3
  • 28
    • 0026625223 scopus 로고
    • Hepatic arterial infusion of floxuridine in patients with liver metastases from colorectal carcinoma: Long-term results of a prospective randomized trial
    • Rougier P, Laplanche A, Huguier M, et al. Hepatic arterial infusion of floxuridine in patients with liver metastases from colorectal carcinoma: long-term results of a prospective randomized trial. J Clin Oncol 1992; 10: 1112-8.
    • (1992) J Clin Oncol , vol.10 , pp. 1112-1118
    • Rougier, P.1    Laplanche, A.2    Huguier, M.3
  • 29
    • 0028150629 scopus 로고
    • Quality of life and survival with continuous hepaticartery floxuridine infusion for colorectal liver metastases
    • Allen-Mersh TG, Earlam S, Fordy C, Abrams K, Houghton J. Quality of life and survival with continuous hepaticartery floxuridine infusion for colorectal liver metastases. Lancet 1994; 344: 1255-60.
    • (1994) Lancet , vol.344 , pp. 1255-1260
    • Allen-Mersh, T.G.1    Earlam, S.2    Fordy, C.3    Abrams, K.4    Houghton, J.5
  • 30
    • 0027972726 scopus 로고
    • Topoisomerase I inhibitors: Topotecan and irinotecan
    • Creemers GJ, Lund B, Verweij J. Topoisomerase I inhibitors: topotecan and irinotecan. Cancer Treat Rev 1994; 20: 73-96.
    • (1994) Cancer Treat Rev , vol.20 , pp. 73-96
    • Creemers, G.J.1    Lund, B.2    Verweij, J.3
  • 31
    • 0024420685 scopus 로고
    • Arrest of replication forks by drug-stabilised topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
    • Hsiang YH, Lihou MG, Liu LF. Arrest of replication forks by drug-stabilised topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Res 1989; 49: 5077-82.
    • (1989) Cancer Res , vol.49 , pp. 5077-5082
    • Hsiang, Y.H.1    Lihou, M.G.2    Liu, L.F.3
  • 32
    • 0024358188 scopus 로고
    • DNA topoisomerase I targeted chemotherapy of human colon cancer in xenografts
    • Giovanella BC, Stehlin JS, Wall ME, et al. DNA topoisomerase I targeted chemotherapy of human colon cancer in xenografts. Science 1989; 246: 1046-8.
    • (1989) Science , vol.246 , pp. 1046-1048
    • Giovanella, B.C.1    Stehlin, J.S.2    Wall, M.E.3
  • 34
    • 0015044313 scopus 로고
    • Studies on the antitumour activity, mechanism of action and cell cycle effects of camptothecin
    • Gallo RC, Whang-Peng J, Adamson RH. Studies on the antitumour activity, mechanism of action and cell cycle effects of camptothecin. J Natl Cancer Inst 1971; 46: 789-95.
    • (1971) J Natl Cancer Inst , vol.46 , pp. 789-795
    • Gallo, R.C.1    Whang-Peng, J.2    Adamson, R.H.3
  • 35
    • 0027194943 scopus 로고
    • Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer
    • Shimada Y, Yashino M, Wakui A, et al. Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer. J Clin Oncol 1993; 11: 909-13.
    • (1993) J Clin Oncol , vol.11 , pp. 909-913
    • Shimada, Y.1    Yashino, M.2    Wakui, A.3
  • 36
    • 0000484557 scopus 로고
    • Irinotecan (CPT-11) is an active agent in untreated patients with metastatic colorectal cancer (CRC)
    • abstr 565
    • Conti JA, Kemeny N, Saltz L, Tong W, Chou TC, Pulliam M. Irinotecan (CPT-11) is an active agent in untreated patients with metastatic colorectal cancer (CRC). Proc Am Soc Clin Oncol 1994; 13: 195 (abstr 565).
    • (1994) Proc Am Soc Clin Oncol , vol.13 , pp. 195
    • Conti, J.A.1    Kemeny, N.2    Saltz, L.3    Tong, W.4    Chou, T.C.5    Pulliam, M.6
  • 37
    • 0001271895 scopus 로고
    • A phase II trial of CPT-11 (irinotecan) in patients with metastatic colorectal carcinoma: A North Central Cancer Treatment Group (NCCTG) study
    • abstr 573
    • Pitot HC, Wender D, O'Connell MJ, Wieand HS, Mailliard JA. A phase II trial of CPT-11 (irinotecan) in patients with metastatic colorectal carcinoma: a North Central Cancer Treatment Group (NCCTG) study. Proc Am Soc Clin Oncol 1994; 13: 197 (abstr 573).
    • (1994) Proc Am Soc Clin Oncol , vol.13 , pp. 197
    • Pitot, H.C.1    Wender, D.2    O'Connell, M.J.3    Wieand, H.S.4    Mailliard, J.A.5
  • 38
    • 0000484548 scopus 로고
    • Irinotecan (CPT-11) as second line therapy for PTS with 5-FU-refractory colorectal cancer
    • abstr 578
    • Rothenberg ML, Eckardt JR, Burris III HA, et al. Irinotecan (CPT-11) as second line therapy for PTS with 5-FU-refractory colorectal cancer. Proc Am Soc Clin Oncol 1994; 13: 198 (abstr 578).
    • (1994) Proc Am Soc Clin Oncol , vol.13 , pp. 198
    • Rothenberg, M.L.1    Eckardt, J.R.2    Burris III, H.A.3
  • 39
    • 8244239609 scopus 로고
    • Clinical efficacy of CPT-11 in patients with inoperable advanced colorectal cancer (CRC): Results of a multicentric open phase II study
    • Paris, France, abstr
    • Rougier P, Bugat R, Brunet P, et al. Clinical efficacy of CPT-11 in patients with inoperable advanced colorectal cancer (CRC): results of a multicentric open phase II study. In: 5th Int Congr of Anti-Cancer Chemotherapy, Paris, France, 1995: S775 (abstr).
    • (1995) 5th Int Congr of Anti-Cancer Chemotherapy
    • Rougier, P.1    Bugat, R.2    Brunet, P.3
  • 40
    • 0343792451 scopus 로고    scopus 로고
    • CPT-11 in the treatment of colorectal cancer (CRC): Safety profile
    • Paris, France 995: abstr
    • Bugat R. CPT-11 in the treatment of colorectal cancer (CRC): safety profile. In: 5th Int Congr of Anti-Cancer Chemotherapy, Paris, France 995: S778 (abstr).
    • 5th Int Congr of Anti-Cancer Chemotherapy
    • Bugat, R.1
  • 41
    • 0028346901 scopus 로고
    • Irinotecan (CPT-11) high-dose escalation using intensive high-dose loperamide to control diarrhea
    • Abigerges D, Armand JP, Chabot G, et al. Irinotecan (CPT-11) high-dose escalation using intensive high-dose loperamide to control diarrhea. J Natl Cancer Inst 1994; 86: 446-9.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 446-449
    • Abigerges, D.1    Armand, J.P.2    Chabot, G.3
  • 42
    • 0029161432 scopus 로고
    • A new enkephalinase inhibitor as an alternative to loperamide in the prevention of diarrhea induced by CPT-11
    • Goncalves E, de-Costa L, Abigerges D, Armand JP. A new enkephalinase inhibitor as an alternative to loperamide in the prevention of diarrhea induced by CPT-11. J Clin Oncol 1995; 13: 2144-6.
    • (1995) J Clin Oncol , vol.13 , pp. 2144-2146
    • Goncalves, E.1    De-Costa, L.2    Abigerges, D.3    Armand, J.P.4
  • 43
    • 0001209644 scopus 로고
    • Pathophysiology and therapy of irinotecan (CPT-11) induced delayed diarrhea (DD). A prospective assessment
    • abstr 1499
    • Hagipantelli R, Saliba F, Misset JL, et al. Pathophysiology and therapy of irinotecan (CPT-11) induced delayed diarrhea (DD). A prospective assessment. Proc Am Soc Clin Oncol 1995; 14: 464 (abstr 1499).
    • (1995) Proc Am Soc Clin Oncol , vol.14 , pp. 464
    • Hagipantelli, R.1    Saliba, F.2    Misset, J.L.3
  • 44
    • 0001730741 scopus 로고
    • A phase II trial of topotecan (TPT) for the treatment of advanced measureable colorectal cancer
    • abstr 684
    • Sugarman SM, Ajani JA, Daugherty K, et al. A phase II trial of topotecan (TPT) for the treatment of advanced measureable colorectal cancer. Proc Am Soc Clin Oncol 1994; 13: 224 (abstr 684).
    • (1994) Proc Am Soc Clin Oncol , vol.13 , pp. 224
    • Sugarman, S.M.1    Ajani, J.A.2    Daugherty, K.3
  • 45
    • 0342954179 scopus 로고
    • In vivo efficacy of two new water-soluble camptothecin analogs in the human cancer xenograft model
    • abstr
    • Emerson DL, Vuong DL, McIntyre MS, et al. In vivo efficacy of two new water-soluble camptothecin analogs in the human cancer xenograft model. Proc Am Ass Cancer Res 1993; 34: 419 (abstr).
    • (1993) Proc Am Ass Cancer Res , vol.34 , pp. 419
    • Emerson, D.L.1    Vuong, D.L.2    McIntyre, M.S.3
  • 46
    • 1642590552 scopus 로고
    • Phase I trial of GG211, a new topoisomerase inhibitor, using a 72 hour continuous infusion (CI)
    • abstr 1525
    • O'Dwyer P, Cassidy J, Kunka R, et al. Phase I trial of GG211, a new topoisomerase inhibitor, using a 72 hour continuous infusion (CI). Proc Am Soc Clin Oncol 1995; 14: 471 (abstr 1525).
    • (1995) Proc Am Soc Clin Oncol , vol.14 , pp. 471
    • O'Dwyer, P.1    Cassidy, J.2    Kunka, R.3
  • 47
    • 0024595925 scopus 로고
    • Clinical pharmacology of 5-fluorouracil
    • Diasio RB, Harris BE. Clinical pharmacology of 5-fluorouracil. Clin Pharmacokinet 1989; 16: 215-37.
    • (1989) Clin Pharmacokinet , vol.16 , pp. 215-237
    • Diasio, R.B.1    Harris, B.E.2
  • 48
    • 0027811090 scopus 로고
    • The role of the reduced-folate carrier and metabolism to intracellular polyglutamates for the activity of ICI D1694
    • Jackman AL, Gibson W, Brown M, Kimbell R, Boyle FT. The role of the reduced-folate carrier and metabolism to intracellular polyglutamates for the activity of ICI D1694. Adv Exp Med Biol 1993; 339: 265-76.
    • (1993) Adv Exp Med Biol , vol.339 , pp. 265-276
    • Jackman, A.L.1    Gibson, W.2    Brown, M.3    Kimbell, R.4    Boyle, F.T.5
  • 49
    • 9044245305 scopus 로고    scopus 로고
    • Tomudex® (ZD1694), a novel thymidylate synthase inhibitor has substantial activity in the treatment of patients with advanced colorectal cancer. Tomudex Colorectal Study Group
    • Zalcberg JR, Cunningham D, Van Cutsem E, et al. Tomudex® (ZD1694), a novel thymidylate synthase inhibitor has substantial activity in the treatment of patients with advanced colorectal cancer. Tomudex Colorectal Study Group. J Clin Oncol 1996; 14: 716-21.
    • (1996) J Clin Oncol , vol.14 , pp. 716-721
    • Zalcberg, J.R.1    Cunningham, D.2    Van Cutsem, E.3
  • 50
    • 0001252836 scopus 로고
    • Tomudex (ZD1694): Results of a randomised trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leucopenia
    • Cunningham D, Zalberg JR, Rath U, et al. Tomudex (ZD1694): results of a randomised trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leucopenia. Eur J Cancer 1995; 31A: 1945-54.
    • (1995) Eur J Cancer , vol.31 A , pp. 1945-1954
    • Cunningham, D.1    Zalberg, J.R.2    Rath, U.3
  • 51
    • 0027417437 scopus 로고
    • The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international trials in oncology
    • Aaronsen NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international trials in oncology. J Natl Cancer Inst 1993; 85: 365-76.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 365-376
    • Aaronsen, N.K.1    Ahmedzai, S.2    Bergman, B.3
  • 52
    • 2642613167 scopus 로고
    • N-[4-[2-(2-amino-4(3H)-oxo-7H-pyrrolo [2,3-d] pyrimidin-5-yl) ethyl] benzoyl]-L-glutamatic acid: A new and potent inhibitor of thymidylate synthase
    • Amsterdam abstr
    • Shih C, Grindley GB, Engelhardt JA, et al. N-[4-[2-(2-amino-4(3H)-oxo-7H-pyrrolo [2,3-d] pyrimidin-5-yl) ethyl] benzoyl]-L-glutamatic acid: a new and potent inhibitor of thymidylate synthase. In: 7th NCI-EORTC Symp on New Drugs Cancer Therapy, Amsterdam 1992: 134 (abstr).
    • (1992) 7th NCI-EORTC Symp on New Drugs Cancer Therapy , pp. 134
    • Shih, C.1    Grindley, G.B.2    Engelhardt, J.A.3
  • 53
    • 2642618936 scopus 로고
    • Clinical phase I study of LY231514 (an inhibitor of thymidylate synthase) using a daily × 5 q 21 schedule
    • abstr 237
    • Vasey PA, Calvert AH, Kaye SB, Cassidy J. Clinical phase I study of LY231514 (an inhibitor of thymidylate synthase) using a daily × 5 q 21 schedule. Ann Oncol 1994; 5 (suppl 5): 131 (abstr 237).
    • (1994) Ann Oncol , vol.5 , Issue.5 SUPPL. , pp. 131
    • Vasey, P.A.1    Calvert, A.H.2    Kaye, S.B.3    Cassidy, J.4
  • 54
    • 15644383860 scopus 로고
    • Experimental antitumor activity of AG-331, a novel lipophilic thymidylate synthase inhibitor
    • Amsterdam abstr
    • Johnston AL, Shetty BV, Webber S, et al. Experimental antitumor activity of AG-331, a novel lipophilic thymidylate synthase inhibitor. In: 7th NCI-EORTC Symp on New Drugs Cancer Therapy, Amsterdam 1992: 131 (abstr).
    • (1992) 7th NCI-EORTC Symp on New Drugs Cancer Therapy , pp. 131
    • Johnston, A.L.1    Shetty, B.V.2    Webber, S.3
  • 55
    • 0001104819 scopus 로고
    • ZD9331, a novel non-polyglutamated thymidylate synthase (TS) inhibitor: In vivo antitumour efficacy and toxicity to normal murine tissues
    • abstr 1816
    • Stephens TC, Smith MN, McCloskey ML, et al. ZD9331, a novel non-polyglutamated thymidylate synthase (TS) inhibitor: in vivo antitumour efficacy and toxicity to normal murine tissues. Proc Am Ass Cancer Res 1994; 35: 305 (abstr 1816).
    • (1994) Proc Am Ass Cancer Res , vol.35 , pp. 305
    • Stephens, T.C.1    Smith, M.N.2    McCloskey, M.L.3
  • 56
    • 0028274226 scopus 로고
    • Destruction of WiDr multicellular tumor spheroids with the novel thymidylate synthase inhibitor 1843U89 at physiological thymidine concentrations
    • Banks SD, Waters KA, Barrett LL, et al. Destruction of WiDr multicellular tumor spheroids with the novel thymidylate synthase inhibitor 1843U89 at physiological thymidine concentrations. Cancer Chemother 1994; 33: 455-9.
    • (1994) Cancer Chemother , vol.33 , pp. 455-459
    • Banks, S.D.1    Waters, K.A.2    Barrett, L.L.3
  • 57
    • 0000410062 scopus 로고
    • Neurotoxicity of long run oxaliplatin (L-OHP®) therapy
    • abstr 2421
    • Brienza S, Fandi A, Hugret F, et al. Neurotoxicity of long run oxaliplatin (L-OHP®) therapy. Proc Am Ass Cancer Res 1993; 34: 406 (abstr 2421).
    • (1993) Proc Am Ass Cancer Res , vol.34 , pp. 406
    • Brienza, S.1    Fandi, A.2    Hugret, F.3
  • 58
    • 0027310715 scopus 로고
    • Oxaliplatin activity against metastatic colorectal cancer. A phase II study of 5-day continuous venous infusion at circadian rhythm modulated rate
    • Levi F, Perpoint B, Garufi C, et al. Oxaliplatin activity against metastatic colorectal cancer. A phase II study of 5-day continuous venous infusion at circadian rhythm modulated rate. Eur J Cancer 1993; 29A: 1280-4.
    • (1993) Eur J Cancer , vol.29 A , pp. 1280-1284
    • Levi, F.1    Perpoint, B.2    Garufi, C.3
  • 59
    • 0000319510 scopus 로고
    • Intensified (every 2 weeks) chronotherapy with 5-fluorouracil (5-FU), folinic acid (FA) and oxaliplatin (L-OHP) in previously treated patients (pts) with metastatic colorectal cancer
    • abstr 577
    • Brienza S, Levi F, Valori VM, et al. Intensified (every 2 weeks) chronotherapy with 5-fluorouracil (5-FU), folinic acid (FA) and oxaliplatin (L-OHP) in previously treated patients (pts) with metastatic colorectal cancer. Proc Am Soc Clin Oncol 1993; 12: 197 (abstr 577).
    • (1993) Proc Am Soc Clin Oncol , vol.12 , pp. 197
    • Brienza, S.1    Levi, F.2    Valori, V.M.3
  • 60
    • 0026512446 scopus 로고
    • A chronopharmacologic phase II clinical trial with 5-fluorouracil, folinic acid, and oxaliplatin using an ambulatory multichannel programmable pump
    • Lévi F, Misset JL, Brienza S, et al. A chronopharmacologic phase II clinical trial with 5-fluorouracil, folinic acid, and oxaliplatin using an ambulatory multichannel programmable pump. Cancer 1992; 69: 893-900.
    • (1992) Cancer , vol.69 , pp. 893-900
    • Lévi, F.1    Misset, J.L.2    Brienza, S.3
  • 61
    • 0028036652 scopus 로고
    • Chronomodulated versus fixed-infusion-rate delivery of ambulatory chemotherapy with oxaliplatin, fluorouracil, and folinic acid (leucovorin) in patients with colorectal cancer metastases: A randomized multi-institutional trial
    • Lévi F, Zidani R, Vannetzel JM, et al. Chronomodulated versus fixed-infusion-rate delivery of ambulatory chemotherapy with oxaliplatin, fluorouracil, and folinic acid (leucovorin) in patients with colorectal cancer metastases: a randomized multi-institutional trial. J Natl Cancer Inst 1994; 86: 1608-17.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1608-1617
    • Lévi, F.1    Zidani, R.2    Vannetzel, J.M.3
  • 62
    • 15644368006 scopus 로고
    • High-dose folinic acid, 5-fluorouracil 48H-infusion and oxaliplatin in metastatic colorectal cancer
    • Paris, France 0269 (abstr)
    • de Gramont A, Tournigand C, Louvet C, et al. High-dose folinic acid, 5-fluorouracil 48H-infusion and oxaliplatin in metastatic colorectal cancer. In: 5th Int Congr of Anti-Cancer Chemotherapy, Paris, France 1995: 0269 (abstr).
    • (1995) 5th Int Congr of Anti-Cancer Chemotherapy
    • De Gramont, A.1    Tournigand, C.2    Louvet, C.3
  • 63
    • 0000723817 scopus 로고
    • Addition of oxaliplatin (L-OHP®) to chronomodulated (CM) 5-fluorouracil and folinic acid (FA) for reversal of acquired chemoresistance in patients with advanced colorectal cancer (ACC)
    • abstr 446
    • Garufi C, Brienza S, Bensmaine MA, et al. Addition of oxaliplatin (L-OHP®) to chronomodulated (CM) 5-fluorouracil and folinic acid (FA) for reversal of acquired chemoresistance in patients with advanced colorectal cancer (ACC). Proc Am Soc Clin Oncol 1995; 14: 192 (abstr 446).
    • (1995) Proc Am Soc Clin Oncol , vol.14 , pp. 192
    • Garufi, C.1    Brienza, S.2    Bensmaine, M.A.3
  • 64
    • 15644370839 scopus 로고
    • Multicentric phase II study with oxaliplatin (L-OHP®) in 5-Fu refractory patients with advanced colorectal cancer (ACC)
    • Paris, France 0721 (abstr)
    • Diaz-Rubio E, Marty M, Extra JM, et al. Multicentric phase II study with oxaliplatin (L-OHP®) in 5-Fu refractory patients with advanced colorectal cancer (ACC). In: 5th Int Congr of Anti-Cancer Chemotherapy, Paris, France 1995: 0721 (abstr).
    • (1995) 5th Int Congr of Anti-Cancer Chemotherapy
    • Diaz-Rubio, E.1    Marty, M.2    Extra, J.M.3
  • 65
    • 0025995425 scopus 로고
    • The therapeutic use of monoclonal antibodies in colorectal carcinoma
    • Mellstedt H, Frödin J-E, Masucci G, et al. The therapeutic use of monoclonal antibodies in colorectal carcinoma. Semin Oncol 1991; 18: 462-77.
    • (1991) Semin Oncol , vol.18 , pp. 462-477
    • Mellstedt, H.1    Frödin, J.-E.2    Masucci, G.3
  • 66
    • 0028224082 scopus 로고
    • Randomised trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal cancer
    • Riethmüller G, Schneider-Gädicke E, Schlimok G, et al. Randomised trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal cancer. Lancet 1994; 343: 1177-83.
    • (1994) Lancet , vol.343 , pp. 1177-1183
    • Riethmüller, G.1    Schneider-Gädicke, E.2    Schlimok, G.3
  • 67
    • 0027203861 scopus 로고
    • Follow-up study of patients treated with monoclonal antibody-drug conjugate: Report of 77 cases with colorectal cancer
    • Takahashi T, Yamaguchi T, Kitamura K, Noguchi A, Honda M, Otsuji E. Follow-up study of patients treated with monoclonal antibody-drug conjugate: report of 77 cases with colorectal cancer. Jpn J Cancer Res 1993; 84: 976-81.
    • (1993) Jpn J Cancer Res , vol.84 , pp. 976-981
    • Takahashi, T.1    Yamaguchi, T.2    Kitamura, K.3    Noguchi, A.4    Honda, M.5    Otsuji, E.6
  • 68
    • 0027406142 scopus 로고
    • Clinical evaluation of tumor targeting with a high-affinity anti-carcinoembryonic-antigen-specific murine monoclonal antibody, MN-14
    • Sharkey RM, Goldenberg DM, Murthy S, et al. Clinical evaluation of tumor targeting with a high-affinity anti-carcinoembryonic-antigen-specific murine monoclonal antibody, MN-14. Cancer 1993; 71: 208296.
    • (1993) Cancer , vol.71 , pp. 208296
    • Sharkey, R.M.1    Goldenberg, D.M.2    Murthy, S.3
  • 70
    • 15644384394 scopus 로고
    • Development of an effective anti-tumour agent from the monoclonal antibody A33
    • abstr 32
    • King DJ, Antonin P, Turner A, et al. Development of an effective anti-tumour agent from the monoclonal antibody A33. J Immunother 1994; 16: 156 (abstr 32).
    • (1994) J Immunother , vol.16 , pp. 156
    • King, D.J.1    Antonin, P.2    Turner, A.3
  • 71
    • 0024437058 scopus 로고
    • Phase I study of monoclonal antibody-ricin A chain immunotoxin Xoma Zyme-791 in patients with metastatic colorectal cancer
    • Byers VS, Rodvien R, Grant K, et al. Phase I study of monoclonal antibody-ricin A chain immunotoxin Xoma Zyme-791 in patients with metastatic colorectal cancer. Cancer Res 1989; 49: 6153-60.
    • (1989) Cancer Res , vol.49 , pp. 6153-6160
    • Byers, V.S.1    Rodvien, R.2    Grant, K.3
  • 72
    • 0026593928 scopus 로고
    • Immunoconjugates containing novel maytansinoids: Promising anticancer drugs
    • Chart RVJ, Martell BA, Gross JL, et al. Immunoconjugates containing novel maytansinoids: promising anticancer drugs. Cancer Res 1992; 52: 127-31.
    • (1992) Cancer Res , vol.52 , pp. 127-131
    • Chart, R.V.J.1    Martell, B.A.2    Gross, J.L.3
  • 73
    • 0027994031 scopus 로고
    • Matrix metalloproteinase inhibitor BB-94 (batimastat) inhibits human colon tumor growth and spread in a patient-like orthoptic model in nude mice
    • Wang X, Fu X, Brown PD, Crimmin MJ, Hoffman RM. Matrix metalloproteinase inhibitor BB-94 (batimastat) inhibits human colon tumor growth and spread in a patient-like orthoptic model in nude mice. Cancer Res 1994; 54: 4726-8.
    • (1994) Cancer Res , vol.54 , pp. 4726-4728
    • Wang, X.1    Fu, X.2    Brown, P.D.3    Crimmin, M.J.4    Hoffman, R.M.5
  • 74
    • 0028089089 scopus 로고
    • Evaluation of a novel bis-naphthalimide anticancer agent, DMP840, against human xenografts derived from adult, juvenile and pediatric cancers
    • Houghton PJ, Cheshire PJ, Hallman JC, et al. Evaluation of a novel bis-naphthalimide anticancer agent, DMP840, against human xenografts derived from adult, juvenile and pediatric cancers. Cancer Chemother Pharmacol 1994; 33: 265-72.
    • (1994) Cancer Chemother Pharmacol , vol.33 , pp. 265-272
    • Houghton, P.J.1    Cheshire, P.J.2    Hallman, J.C.3
  • 75
    • 0026043265 scopus 로고
    • Phase II study of droloxifene for treatment of metastatic colorectal carcinoma
    • Nienhaus P Queißer W, Heim ME, Pechan R. Phase II study of droloxifene for treatment of metastatic colorectal carcinoma. Onkologie 1991; 14: 401-5.
    • (1991) Onkologie , vol.14 , pp. 401-405
    • Nienhaus, P.1    Queißer, W.2    Heim, M.E.3    Pechan, R.4
  • 77
    • 0027437455 scopus 로고
    • Phase I human clinical trial of ONCONASE (Rm) (P-30 protein) administered intravenously on a weekly schedule in cancer patients with solid tumours
    • Mikulski SM, Grossman AM, Carter PW. Phase I human clinical trial of ONCONASE (Rm) (P-30 protein) administered intravenously on a weekly schedule in cancer patients with solid tumours. Int J Oncol 1993; 3: 57-64.
    • (1993) Int J Oncol , vol.3 , pp. 57-64
    • Mikulski, S.M.1    Grossman, A.M.2    Carter, P.W.3
  • 78
    • 0027489763 scopus 로고
    • 5-Ethynyluracil (776C85): A potent modulator of the pharmacokinetics and antitumour efficacy of 5-fluorouracil
    • Baccanari DP, Davis ST, Knick VC, Spector T. 5-Ethynyluracil (776C85): a potent modulator of the pharmacokinetics and antitumour efficacy of 5-fluorouracil. Proc Natl Acad Sci USA 1993; 90: 11064-8.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11064-11068
    • Baccanari, D.P.1    Davis, S.T.2    Knick, V.C.3    Spector, T.4
  • 79
    • 0025268022 scopus 로고
    • Growth inhibition of marine melanoma and human colon carcinoma by recombinant human platelet factor 4
    • Sharpe RJ, Byers HR, Scott CF, Bauer EI, Maione TE. Growth inhibition of marine melanoma and human colon carcinoma by recombinant human platelet factor 4. J Natl Cancer Inst 1990; 82: 848-53.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 848-853
    • Sharpe, R.J.1    Byers, H.R.2    Scott, C.F.3    Bauer, E.I.4    Maione, T.E.5
  • 80
    • 0027428545 scopus 로고
    • Involvement of T lymphocytes in curative effect of a new immunomodulator OM163 on rat colon cancer metastases
    • Onier N, Lejeune P, Martin M, et al. Involvement of T lymphocytes in curative effect of a new immunomodulator OM163 on rat colon cancer metastases. Eur J Cancer 1993; 29A: 2003-9.
    • (1993) Eur J Cancer , vol.29 A , pp. 2003-2009
    • Onier, N.1    Lejeune, P.2    Martin, M.3
  • 83
    • 0027496518 scopus 로고
    • In vivo antitumour activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase
    • Huber BE, Austin EA, Good SS, Knick VC, Tibbels S, Richards CA. In vivo antitumour activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase. Cancer Res 1993; 53: 4619-26.
    • (1993) Cancer Res , vol.53 , pp. 4619-4626
    • Huber, B.E.1    Austin, E.A.2    Good, S.S.3    Knick, V.C.4    Tibbels, S.5    Richards, C.A.6


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