DACH: Genomic characterization, evaluation as a candidate for postaxial polydactyly type A2, and developmental expression pattern of the mouse homologue

Genomics

Volumn 77, Issue 1-2, 2001, Pages 18-26

  Ayres, Jennifer A ^a   Shum, Lillian ^a   Akarsu, A Nurten ^b   Dashner, Ralph ^a   Takahashi, Katsu ^a   Ikura, Tsuyoshi ^a   Slavkin, Harold C ^a   Nuckolls, Glen H ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Chromosome 13q22; DACH; Dachshund; Ear; Eye; Kidney; Limb; Mutation analysis; Postaxial polydactyly; Transcription factor

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; CELL TYPE; CHROMOSOME 13Q; DROSOPHILA MELANOGASTER; EAR MALFORMATION; EMBRYO; EYE MALFORMATION; FETUS; GENE MUTATION; GENOME; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; KIDNEY MALFORMATION; MOUSE; MULTIPLE MALFORMATION SYNDROME; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYDACTYLY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION;

DROSOPHILA MELANOGASTER;

EID: 0035416490     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.2001.6618     Document Type: Article

References (50)

1. Vertebrate eye development as modeled in Drosophila
2. Targeted expression of teashirt induces ectopic eyes in Drosophila
3. Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation
4. Characterization of mouse Dach2, a homologue of Drosophila dachshund
5. Mouse Dac, a novel nuclear factor with homology to Drosophila dachshund shows a dynamic expression in the neural crest, the eye, the neocortex, and the limb bud
6. Mouse Dach, a homologue of Drosophila dachshund, is expressed in the developing retina, brain and limbs
7. Mammalian and Drosophila dachshund genes are related to the Ski proto-oncogene and are expressed in eye and limb
8. Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene
9. Dachshund and eyes absent proteins form a complex and function synergistically to induce ectopic eye development in Drosophila
10. Ectopic eye development in Drosophila induced by directed dachshund expression
11. Dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila
12. Proximal-distal axis formation in the Drosophila leg
13. Genetic control of development of the mushroom bodies, the associative learning centers in the Drosophila brain, by the eyeless, twin of eyeless, and Dachshund genes
14. The retinal determination gene, dachshund, is required for mushroom body cell differentiation
15. Early development of the Drosophila mushroom body: The roles of eyeless and dachshund
16. Pax2 in development and renal disease
17. The role of Pax-6 in eye and nasal development
18. Pax-6 is first expressed in a region of ectoderm anterior to the early neural plate: Implications for stepwise determination of the lens
19. Spatially and temporally restricted expression of Pax2 during murine neurogenesis
20. Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development
21. Homeobox genes and connective tissue patterning
22. Pax-6, a murine paired box gene, is expressed in the developing CNS
23. Mouse Eya genes are expressed during limb tendon development and encode a transcriptional activation function
24. Yeast two-hybrid system identifies the ubiquitin-conjugating enzyme mUbc9 as a potential partner of mouse Dac
25. Dach1 mutant mice bear no gross abnormalities in eye, limb, and brain development and exhibit postnatal lethality
26. A human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family
27. BOR and BO syndromes are MiMic defects of EYA1
28. PAX6 mutations reviewed
29. PAX2 mutations in renal-coloboma syndrome: Mutational hotspot and germline mosaicism
30. Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux
31. Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly
32. Human (DACH) and mouse (Dach) homologues of Drosophila dachshund map to chromosomes 13q22 and 14E3, respectively
33. Localization of the human homologue of the Drosophila dachshund gene (DACH) to chromosome 13q21
34. Phenotypic mapping in man
35. Partial trisomy 13q resulting from a paternal reciprocal Yq;13q translocation
36. Partial trisomies and deletion of chromosome 13
37. Segregation of digital number with partial monosomy or trisomy of 13q in familial 5;13 translocation
38. Preliminary definition of a critical region of chromosome 13 in q32. Report of 14 cases with 13q deletions and review of the literature
39. Interpreting cDNA sequences: Some insights from studies on translation
40. Hormonal regulation of mRNA stability and RNA-protein interactions in the pituitary
41. Eya1 expression in the developing ear and kidney: Towards the understanding of the pathogenesis of branchio-oto-renal (BOR) syndrome
42. Tissue and developmental distribution of Six family gene products
43. Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode
44. EYA4, a novel vertebrate gene related to Drosophila eyes absent
45. Six6 (Optx2) is a novel murine Six3-related homeobox gene that demarcates the presumptive pituitary/hypothalamic axis and the ventral optic stalk
46. The deltaA gene of zebrafish mediates lateral inhibition of hair cells in the inner ear and is regulated by pax2.1
47. A large Turkish kindred with syndactyly type II (synpolydactyly). 1. Field investigation, clinical and pedigree data
48. Mapping of the second locus of postaxial polydactyly type A (PAP-A2) to chromosome 13q21-q32
49. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
50. Positionally-dependent chondrogenesis induced by BMP4 is co-regulated by Sox9 and Msx2