Continuing ability of the rodent bone marrow micronucleus assay to act as a predictor of the possible germ cell mutagenicity of chemicals

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 478, Issue 1-2, 2001, Pages 211-213

  Ashby, J ^a   Tinwell, H ^a  

^a JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBENDAZIM; CORN OIL; CYCLOPHOSPHAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BONE MARROW; DIPLOIDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; ERYTHROCYTE; GERM CELL; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; MUTAGENICITY; MUTATION; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY;

ANIMALIA; RODENTIA; ZEA MAYS;

EID: 0035400373     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(01)00129-4     Document Type: Article

References (15)

1. Comparison of somatic and germ cell models for cytogenetic screening
2. The prospects for a simplified and internationally harmonised approach to the detection of possible human carcinogens and mutagens
3. The present lack of evidence for unique rodent germ cell mutagens
4. The performance of short-term tests in identifying potential germ cell mutagens: A qualitative and quantitative analysis
5. Selecting chemicals and assays for assessing mammalian germ cell mutagenicity
6. IPCS harmonisation of methods for the prediction and quantification of human carcinogenic/mutagenic hazard, and for indicating the probable mechanism of action of carcinogens
7. Further evidence for the rodent bone marrow micronucleus assay acting as a sensitive predictor of the possible germ cell mutagenicity of chemicals
8. Increased frequencies of diploid sperm detected by multicolour FISH after treatment of rats with carbendazim without micronucleus induction in peripheral blood erythrocytes
9. The persistence of micronucleated erythrocytes in the peripheral circulation of normal and splenectomized Fisher 344 rats: Implications for cytogenetic screening
10. Assessement of the mutagenic potential of a fungicide Bavistin using multiple assays
11. Cytogenetic effects of benzimidazoles in mouse bone marrow
12. Evaluation of benomyl and carbendazim in the in vivo aneuploidy/micronucleus assay in BDF1 mouse bone marrow
13. Transformations related to the angular and the square root