The role of leptin and hypothalamic neuropeptides in energy homeostasis: Update on leptin in obesity

Growth Hormone and IGF Research

Volumn 11, Issue SUPPL. 1, 2001, Pages

  Mantzoros, Christos S ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Energy homeostasis; Leptin; Obesity

Indexed keywords

ANTIOBESITY AGENT; LEPTIN; NEUROPEPTIDE;

ANIMAL; CLINICAL TRIAL; ENDOCRINE SYSTEM; ENERGY METABOLISM; HOMEOSTASIS; HUMAN; HUNGER; HYPOTHALAMUS; METABOLISM; OBESITY; PHYSIOLOGY; REVIEW;

ANIMALS; ANTI-OBESITY AGENTS; CLINICAL TRIALS; ENDOCRINE SYSTEM; ENERGY METABOLISM; HOMEOSTASIS; HUMANS; HUNGER; HYPOTHALAMUS; LEPTIN; NEUROPEPTIDES; OBESITY;

EID: 0035376178     PISSN: 10966374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1096-6374(01)80014-9     Document Type: Review

References (7)

1. Must A, Spadano J, Coakley EH, Field AE, Colditz G, Dietz WH. The disease burden associated with overweight and obesity. JAMA 1999; 282: 1523-1529.
2. Allison DB, Fontaine KR, Manson JE, Stevens J, Vanltallie TB. Annual deaths attributable to obesity in the United States. JAMA 1999; 282: 1530-1538.
3. Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature 1998; 395: 763-770.
4. Mantzoros CS. The role of leptin in human obesity and disease: a review of current evidence. Ann Intern Med 1999; 130: 671-680.
5. Ahima RS, Saper CB, Flier JS, Elmquist JK. Leptin regulation of neuroendocrine systems. Front Neuroendocrinol 2000; 21: 263-307
6. Mantzoros CS, Cogswell RJ. Leptin's role in regulation of neuroendocrine function. Mol Psychiatry 1999; 4: 6-7
7. Ahima RS, Prabakaran D, Mantzoros C, et al. Role of leptin in the neuroendocrine response to fasting. Nature 1996; 382: 250-252.