Role of peroxynitrite in macrophage microbicidal mechanisms in vivo revealed by protein nitration and hydroxylation

Free Radical Biology and Medicine

Volumn 30, Issue 11, 2001, Pages 1234-1242

  Linares, Edlaine ^a   Giorgio, Selma ^b   Mortara, Renato A ^b   Santos, Célio X C ^a   Yamada, Aureo T ^c   Augusto, Ohara ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c Imunologia Parasitol Da Univ F   (Brazil)

Author keywords

Carbonate radical anion; Free radicals; Intracellular microorganisms; Leishmania; Macrophage derived cytotoxins; Nitric oxide; Peroxynitrite; Protein nitration and hydroxylation; Superoxide anion

Indexed keywords

ANION; CARBON DIOXIDE; CARBONIC ACID; CYTOTOXIN; DOPA; HYDROXYL RADICAL; NITRIC OXIDE SYNTHASE; NITROGEN DIOXIDE; PEROXIDASE; PEROXYNITRITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; ELECTRON SPIN RESONANCE; ENZYME LOCALIZATION; FEMALE; HYDROXYLATION; IN VIVO STUDY; INFECTION RESISTANCE; INFECTION SENSITIVITY; LEISHMANIA; LYSOSOME; MACROPHAGE ACTIVATION; MOUSE; NITRATION; NONHUMAN; PARASITE CONTROL; PHAGOCYTOSIS; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE REPAIR;

ANIMALS; CARBON DIOXIDE; CARBONATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIHYDROXYPHENYLALANINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; HYDROXYLATION; LEISHMANIA INFANTUM; LEISHMANIASIS; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PEROXIDASE; PEROXYNITROUS ACID; TYROSINE;

EID: 0035370287     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00516-0     Document Type: Article

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