Human acrocentric chromosomes with transcriptionally silent nucleolar organizer regions associate with nucleoli

EMBO Journal

Volumn 20, Issue 11, 2001, Pages 2867-2877

  Sullivan, Gareth J ^a   Bridger, Joanna M ^b   Cuthbert, Andrew P ^b,c   Newbold, Robert F ^b   Bickmore, Wendy A ^d   McStay, Brian ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b BRUNEL UNIVERSITY   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Human acrocentric chromosomes; Nucleolar organizer regions; Nucleoli; Somatic cell hybrids; UBF

Indexed keywords

RIBOSOME DNA;

ACROCENTRIC CHROMOSOME; ANIMAL CELL; ARTICLE; CHROMOSOME NOR; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC TRANSCRIPTION; HYBRID CELL; MOUSE; NONHUMAN; NUCLEOLUS; PRIORITY JOURNAL;

ANIMALS; CELL LINE; CELL NUCLEUS; CHROMOSOMES, HUMAN; DNA, RIBOSOMAL; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; HELA CELLS; HUMANS; HYBRID CELLS; IN SITU HYBRIDIZATION, FLUORESCENCE; METAPHASE; MICE; NUCLEOLUS ORGANIZER REGION; POLYMERASE CHAIN REACTION; RNA, RIBOSOMAL, 28S; TRANSCRIPTION, GENETIC;

EID: 0035355351     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.11.2867     Document Type: Article

References (53)

1. Characterisation of transcriptionally active and inactive chromatin domains in neurons
2. The nucleolar cycle in man
3. Structural and functional aspects of nucleolar organizer regions (NORs) of human chromosomes
4. Functional cooperativity between transcription factors UBF1 and SL1 mediates human ribosomal RNA synthesis
5. Inhibition of nucleolar reformation after microinjection of antibodies to RNA polymerase I into mitotic cells
6. Putting the genome on the map
7. Analysis of mammalian interphase chromosomes by FISH and immunofluorescence
8. 1 cells
9. Identification and cDNA cloning of a Xenopus nucleolar phosphoprotein, xNopp180, that is the homolog of the rat nucleolar protein Nopp140
10. To be or not to be in the nucleolus
11. Human autoantibody to RNA polymerase I transcription factor hUBF. Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factor
12. A homologous subfamily of satellite III DNA on human chromosomes 14 and 22
13. The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SLI
14. Construction and characterization of a highly stable human:rodent monochromosomal hybrid panel for genetic complementation and genome mapping studies
15. Transcription in the yeast rRNA gene locus: Distribution of the active gene copies and chromatin structure of their flanking regulatory sequences
16. Initiation of nucleolar assembly is independent of RNA polymerase I transcription
17. Visualization of nucleolar organizer regions in mammalian chromosomes using silver staining
18. Regulation of mammalian ribosomal gene transcription by RNA polymerase I
19. Chromosome arm painting probes
20. Species specificity of transcription by RNA polymerase I
21. Electron tomography of metaphase nucleolar organizer regions: Evidence for a twisted-loop organization
22. Location of ribosomal DNA in the human chromosome complement
23. Nucleologenesis: U3 snRNA-containing prenucleolar bodies move to sites of active pre-rRNA transcription after mitosis
24. In vivo evidence that TATA-binding protein/SL1 colocalizes with UBF and RNA polymerase I when rRNA synthesis is either active or inactive
25. Repositioning of human interphase chromosomes by nucleolar dynamics in the reverse transformation of HT1080 fibrosarcoma cells
26. Mitotic phosphorylation of the TBP-containing factor SL1 represses ribosomal gene transcription
27. Characterization of three sites of RNA 3′ end formation in the Xenopus ribosomal gene spacer
28. Interactive computer-assisted analysis of chromosome 1 colocalization with nucleoli
29. Some properties of isolated nucleoli from guinea-pig liver
30. Reproducible compartmentalization of individual chromosome domains in human CNS cells revealed by in situ hybridization and three-dimensional reconstruction
31. Nuclear bodies: Multifaceted subdomains of the interchromatin space
32. Expression of human and suppression of mouse nucleolus organizer activity in mouse-human somatic cell hybrids
33. Quantitative aspects of isolation of nucleoli of the Walker carcinosarcoma and liver of the rat
34. Centromere autoantigens are associated with the nucleolus
35. Nucleologenesis: Composition and fate of prenucleolar bodies
36. The nucleolus: An old factory with unexpected capabilities
37. Spatial rearrangement and enhanced clustering of kinetochores in interphase nuclei of dorsal root ganglion neurons in vitro: Association with nucleolar fusion
38. The plurifunctional nucleolus
39. UBF, an architectural element for RNA polymerase I promoters
40. Localization of the RNA polymerase I transcription factor hUBF during the cell cycle
41. The rDNA transcription machinery is assembled during mitosis in active NORs and absent in inactive NORs
42. Human ribosomal RNA gene cluster: Identification of the proximal end containing a novel tandem repeat sequence
43. Structure and function of the nucleolus
44. The nucleolus
45. Analysis of ribosomal and alphoid repetitive DNA by fiber-FISH
46. Contiguous arrays of satellites 1, 3 and β form a 1.5-Mb domain on chromosome 22p
47. In vivo release of mitotic silencing of ribosomal gene transcription does not give rise to precursor ribosomal RNA processing
48. Reactivation of ribosomal RNA genes in human-mouse hybrid cells by 12-O-tetradecanoylphorbol 13-acetate
49. Assignment of human satellite 1 DNA as revealed by fluorescent in situ hybridization with oligonucleotides
50. 1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF
51. Concerted evolution of α satellite DNA: Evidence for species specificity and a general lack of sequence conservation among alphoid sequences of higher primates
52. Spatial distribution of sex chromosomes and ribosomal genes: A study on human lymphocytes and testicular cells
53. A possible mechanism for the inhibition of ribosomal RNA gene transcription during mitosis