Plasmodium falciparum: Emerging mefloquine resistance in vitro in Para State, north Brazil

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 95, Issue 3, 2001, Pages 330-331

  Calvosa, V S P ^a   Adagu, I S ^b   Povoa M M ^a  

^a INSTITUTO EVANDRO CHAGAS   (Brazil)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTIMALARIAL AGENT; CG2 PROTEIN, PLASMODIUM FALCIPARUM; MDR GENE PROTEIN, PLASMODIUM; MEFLOQUINE; PROTOZOAL PROTEIN;

ANIMAL; ARTICLE; BRAZIL; DRUG EFFECT; GENETICS; HUMAN; MALARIA FALCIPARUM; MULTIDRUG RESISTANCE; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; ATP-BINDING CASSETTE TRANSPORTERS; BRAZIL; DRUG RESISTANCE, MULTIPLE; HUMANS; MALARIA, FALCIPARUM; MEFLOQUINE; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS;

EID: 0035350482     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(01)90255-X     Document Type: Article

References (9)

1. Couto, A. A., Calvosa, V. S., Lima, J. E. & Souza, J. M. (1993). The evolution of in-vitro resistance in Plasmodium falciparum to antimalarials in a gold-prospecting area in the state of Amapa between 1983 and 1993. Revista da Sociedade Brasileira de Medicina Tropical, 26, 215-220.
2. Couto, A. A., Calvosa, V. S., Santos, M. A. & Souza, J. M. (1995). The evolution over time of the in-vitro resistance of Plasmodium falciparum to antimalarial drugs in 2 areas of the Brasilian Amazonia with distinct socioeconomic and geographic characteristics. Revista da Sociedade Brasileira de Medicina Tropical, 28, 357-365.
3. Di Santi, S. M., Neves, V. L. F. C., Boulos, M., Dutra, A. P., Ramos, A. M. S. V., Santos, M. & Barata, L. C. B. (1988). Avaliation of response of Plasmodium falciparum to chloroquine, quinine and mefloquine. Revista do Instituto Medicina Tropical de São Paulo, 30, 147-152.
4. Lasserre, R. (1989). The treatment of multiresistant falciparum malaria in Southeast Asia. Bulletin de la Société de Pathologie Exotique et de ses Filiales, 82, 94-100.
5. Oduola, A. M., Sowunmi, A., Milhous, W. K., Kyle, D. E., Martin, R. K., Walker, O. & Salako, L. A. (1992). Innate resistance to new antimalarial drugs in Plasmodium falciparum from Nigeria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 86, 123-126.
6. Tyr polymorphisms are present in chloroquine-resistant and sensitive Brazilian field isolates of Plasmodium falciparum. Experimental Parasitology, 88, 64-68.
7. Price, R. N., Nosten, F., Luxemburger, C., van Vugt, M., Phaipun, L., Chongsuphajaisiddhi, T. & White, N. J. (1999). Artesunate/mefloquine treatment of multi-drug resistant falciparum malaria. American Journal of Tropical Medicine and Hygiene, 61, 114-119.
8. WHO (1990). In vitro micro-test (Mark-II) for the assessment of the response of Plasmodium falciparum to chloroquine, mefloquine, quinine, sulphadoxine/pyrimethamine and amodiaquine. Geneva, Switzerland: World Health Organization. MAP/ 87.2.
9. Zalis, M. G., Pang, L., Silveira, M. S., Milhous, W. K. & Wirth, D. F. (1998). Characterization of Plasmodium falciparum isolates from Amazon region of Brazil: evidence for quinine resistance. American Journal of Tropical Medicine and Hygiene, 58, 630-637.