Site-specific adaptive remodeling of Greyhound metacarpal cortical bone subjected to asymmetrical cyclic loading

American Journal of Veterinary Research

Volumn 62, Issue 5, 2001, Pages 787-793

  Johnson, Kenneth A ^a,b   Skinner, Gerry A ^b   Muir, Peter ^c  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; ANIMAL; ANIMAL DISEASE; ARTICLE; BONE REMODELING; COMPARATIVE STUDY; CYTOCHEMISTRY; DOG; FORELIMB; HAVERSIAN CANAL; HISTOLOGY; METACARPAL BONE; MICROSCOPY; PHYSIOLOGY;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BONE REMODELING; DOGS; FORELIMB; HAVERSIAN SYSTEM; HISTOCYTOCHEMISTRY; METACARPUS; MICROSCOPY, VIDEO;

EID: 0035349841     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2001.62.787     Document Type: Article

References (42)

1. Bellenger CR, Johnson KA, Davis PE, et al. Fixation of metacarpal and metatarsal fractures in Greyhounds. Aust Vet J 1981; 57:205-211.
2. Boemo CM. Injuries of the metacarpus and metatarsus. In: Bloomberg MS, Dee JF, Taylor RA, eds. Canine sports medicine and surgery. Philadelphia: WB Saunders Co, 1998;150-165.
3. Dee JF, Dee LG, Eaton-Wells RD. Injuries of high performance dogs. In: Whittick WC, ed. Canine orthopaedics. 2nd ed. Philadelphia: Lea & Febiger, 1990;519-570.
4. Brukner P, Bradshaw C, Khan KM, et al. Stress fractures: a review of 180 cases. Clin J Sport Med 1996;6:85-89.
5. Nunamaker DM, Butterweck DM, Provost MT. Fatigue fractures in Thoroughbred racehorses: relationships with age, peak bone strain, and training. J Orthop Res 1990;8:604-611.
6. Stover SM, Johnson BJ, Daft BM, et al. An association between complete and incomplete stress fractures of the humerus in racehorses. Equine Vet J 1992;24:260-263.
7. Cline AD, Jansen GR, Melby CL. Stress fractures in female army recruits: implications of bone density, calcium intake, and exercise. J Am Coll Nutr 1998;17:128-135.
8. Sicard GK, Short K, Manley PA. A survey of injuries at five Greyhound racing tracks. J Small Anim Pract 1999;40:428-432.
9. Lanyon LE. Control of bone architecture by functional load bearing. J Bone Miner Res 1992;7:S369-S375.
10. Lanyon LE, Baggott DG. Mechanical function as an influence on the structure and form of bone. J Bone Joint Surg Am 1976; 58:436-443.
11. Lanyon LE, Bourn S. The influence of mechanical function on the development and remodeling of the tibia. J Bone Joint Surg Am 1979;61:263-273.
12. Haapasalo H, Sievanen H, Kannus P, et al. Dimensions and estimated mechanical characteristics of the humerus after long-term tennis loading. J Bone Joint Surg Am 1996;11:864-872.
13. Jones HH, Priest JD, Hayes WC, et al. Humeral hypertrophy in response to exercise. J Bone Joint Surg Am 1977;59:204-208.
14. Goodship AE, Lanyon LE, McFie H. Functional adaptation of bone to increased stress. An experimental study. J Bone Joint Surg Am 1979;61:539-546.
15. McCarthy RN, Jeffcott LB. Effects of treadmill exercise on cortical bone in the third metacarpus of young horses. Res Vet Sci 1992;52:28-37.
16. Nunamaker DM, Butterweck DM, Provost MT. Some geometric properties of the third metacarpal bone: a comparison between the Thoroughbred and Standardbred racehorse. J Biomech 1989; 22:129-134.
17. Sherman KM, Miller GJ, Wronski TJ, et al. The effect of training on equine metacarpal bone breaking strength. Equine Vet J 1995;27:135-139.
18. Stover SM, Pool RR, Martin RB, et al. Histological features of the dorsal cortex of the third metacarpal bone mid-diaphysis during post-natal growth in thoroughbred horses. J Anat 1992;181:455-469.
19. Boyde A, Riggs CM. The quantitative study of the orientation of collagen in compact bone slices. Bone 1990;11:35-39.
20. Riggs CM, Lanyon LE, Boyde A. Functional associations between collagen fiber orientation and locomotion strain direction in cortical bone of the equine radius. Anat Embryol (Berl) 1993;187:231-238.
21. Skerry TM. Identification of novel signaling pathways during functional adaptation of the skeleton to mechanical loading: the role of glutamate as a paracrine signaling agent in the skeleton. J Bone Miner Metab 1999;17:66-70.
22. Mori S, Burr DB. Increased intracortical remodeling following fatigue damage. Bone 1993;14:103-109.
23. Bentolila V, Boyce TM, Fyhrie DP, et al. Intracortical remodeling in adult rat long bones after fatigue loading. Bone 1998;23:275-281.
24. Burr DB. Bone, exercise and stress fracture. Exerc Sport Sci Rev 1997;25:171-194.
25. Nagurka ML, Hayes WC. An interactive graphics package for calculating cross-sectional properties of complex shapes. J Biomech 1980;13:59-64.
26. Mason MW, Skedros JG, Bloebaum RD. Evidence of strain-mode-related cortical adaptation in the diaphysis of the horse radius. Bone 1995;17:229-237.
27. Martin RB, Lau ST, Mathews PV, et al. Collagen fiber organization is related to mechanical properties and remodeling in equine bone. A comparison of two methods. J Biomech 1996;29:1515-1521.
28. Markel MD, Sielman E. Radiographic study of homotypic variation of long bones in dogs. Am J Vet Res 1993;54:2000-2003.
29. Rubin CT, Gross TS, McLeod KJ, et al. Morphologic stages in lamellar bone formation stimulated by a potent mechanical stimulus. J Bone Miner Res 1995;10:488-495.
30. Hayes WC. Biomechanics of cortical and trabecular bone: implications for assessment of fracture risk. In: Mow VC, Hayes WC, eds. Basic orthopaedic biomechanics. New York: Raven Press, 1991;93-142.
31. Carter DR, Spengler DM. Biomechanics of fracture. In: Sumner-Smith G, ed. Bone in clinical orthopaedics. Philadelphia: WB Saunders Co, 1982;305-334.
32. Martin RB, Burr DB. Structure, function, and adaptation of compact bone. New York: Raven Press, 1989;105-185.
33. Parfitt AM. The mechanism of coupling: a role for the vasculature. Bone 2000;26:319-323.
34. Ascenzi A, Bonucci E. The compressive properties of single osteons. Anat Rec 1968;161:377-391.
35. Martin RB, Gibson VA, Stover SM, et al. Osteonal structure in the equine third metacarpus. Bone 1996;19:165-171.
36. Martin RB, Ishida J. The relative effects of collagen fiber orientation, porosity, density, and mineralization on bone strength. J Biomech 1989;22:419-426.
37. Takano Y, Turner CH, Owan I, et al. Elastic anisotropy and collagen orientation of osteonal bone are dependent on the mechanical strain distribution. J Orthop Res 1999;17:59-66.
38. Burr DB, Martin RB, Schaffler MB, et al. Bone remodeling in response to in vivo fatigue microdamage. J Biomech 1985;18: 189-200.
39. Tomlin JL, Lawes TJ, Blunn GW, et al. Fractographic examination of racing greyhound central (navicular) tarsal bone failure surfaces using scanning electron microscopy. Calcif Tissue Int 2000;67:260-266.
40. Johnson KA, Muir P, Nicoll RG, et al. Asymmetric adaptive modeling of central tarsal bones in racing Greyhounds. Bone 2000;27:257-263.
41. Muir P, Johnson KA, Ruaux-Mason C. In vivo matrix microdamage in a naturally occurring canine fatigue fracture. Bone 1999;25:571-576.
42. Myers ER, Hecker AT, Rooks DS, et al. Geometric variables from DXA of the radius predict forearm fracture load in vitro. Calcif Tissue Int 1993;52:199-204.