Clinical Research on Ayurvedic Therapeutics : Myths, Realities and Challenges

Journal of Association of Physicians of India

Volumn 49, Issue MAY, 2001, Pages 558-562

  Bhatt, A D ^a  

^a Building 3   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AYURVEDA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DOSE RESPONSE; HUMAN; INSTRUMENTATION; MEDICINAL PLANT; METHODOLOGY; PHYTOTHERAPY; RANDOMIZED CONTROLLED TRIAL; RESEARCH; REVIEW; TREATMENT OUTCOME;

DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MEDICINE, AYURVEDIC; PHYTOTHERAPY; PLANTS, MEDICINAL; RANDOMIZED CONTROLLED TRIALS; RESEARCH; TREATMENT OUTCOME;

EID: 0035348579     PISSN: 00045772     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (24)

1. Angell M, Kassirer JP. Alternative medicine - the risks of untested and unregulated remedies. N Eng J Med 1998; 339 : 839-41.
2. Ornish D, Brown S, Scherwitz L, et al. Can lifestyle changes reverse coronary heart disease? The lifestyle heart disease trial. Lancet 1990; 336 : 129-33.
3. Kjeldsen-Kragh J, Haugen M, Borchgrevink C, et al. Controlled trial of fasting and one year vegetarian diet in rheumatoid arthritis. Lancet 1991; 338 : 899-902.
4. Bhatt AD, Bhatt NS. Indigenous drugs and liver disease. Ind J Gastroenterol 1996; 15 : 63-7.
5. Margolin A, Kelly Avants S, Kleber HD. Investigating alternative medicine therapies in randomised controlled trials. JAMA 1998; 280 : 1626-8.
6. Stalker DF. Evidence and alternative medicine. Mount Sinai J Med 1995; 62 : 132-43.
7. Farnsworth NR. Ethnopharmacology and drug development CIBA foundation symposium on ethnobotany and the search for new drugs. Chichester John Wiley 1994; 42-59.
8. Vaidya AB, Antarkar DS. New drugs from medicinal plants : opportunities and approaches. J Assoc Phys Ind 1994; 42 : 221-8.
9. van Riel PLCM, van Gestal AM, van Putte DE. Development and validation of response criteria in rheumatoid arthritis. Brit J Rheum 1996; 35 : s4-7.
10. Pincus T. Long-term outcomes in rheumatoid arthritis. Brit J Rheum 1995; 34 : s59-7.
11. Porter DR, Capell HA. The natural history of active rheumatoid arthritis over 3-6 months - an analysis of patients enrolled into trials of potential disease - modifying antirheumatic drugs, and treated with placebo. Br J Rheumatol 1993; 32: 463-6.
12. Epstein WV. Expectation bias in rheumatoid arthritis clinical trials. The anti CD4 monoclonal antibody experience. Arthritis Rheum 1996; 39 : 1773-80.
13. Indian Council of Medical Research (ICMR), Collaborating Centres, New Delhi. Flexible dose open trial of Vijayasar in cases of newly-diagnosed non-insulin-dependent diabetes mellitus. Ind J Med Res 1998; 108 : 24-9.
14. Nandu VP, Sangani DK, Bhatt AD, Wagle SP, Mehta RH. Short term chemotherapy of pulm/extrapulm kochs with special emphasis on hepatotoxicity of the drugs. J Assoc Phys Ind 1991; 39 : 886.
15. Bensoussan A, Talley NJ, Hing M, Menzies R, Guo A, Ngy M. Treatment of irritable bowel syndrome with Chinese herbal medicine. A randomised controlled trial. JAMA 1998; 280 : 1585-9.
16. Vaidya AB, Antarkar DS, Doshi JC, et al. Picrorhiza kurroa (Kutaki) Royle Ex Benth as a hepatoprotective agent -experimental and clinical studies. J Postgrad Med 1996; 42 : 105-8.
17. Rege N, Bapat RD, Koti R, Desai NK, Dahanukar S. Immunotherapy with Tinospora cordifolia. A new lead in the management of obstructive jaundice. Indian J Gastroenterol 1993; 12 : 5-8.
18. Le Bars PL, Katz MM, Berman N, et al. A placebo-controlled, double-blind, randomized trial of an extract Ginkgo biloba for dementia. North American Egb study group JAMA 1997; 278 : 1327-32.
19. Vorbach EU, Arnoldt KH, Hubner WD. Efficacy and tolerability of St. John's wort extract L1 160 versus imipramine in patients with severe depressive episodes according to ICD-10. Pharmacopsychiat 1997; 30 (Suppl) : 81-5.
20. Gupta I, Gupta V, Parihar A, et al. Effects of Boswellia serrata gum resin in patients with bronchial asthma results of a double-blind, six week clinical study. Eur J Med Res 1998; 3 : 511-4.
21. Bhatt AD, Dalal DG, Shah SJ, et al. Conceptual and methodologic challenges of assessing the short-term efficacy of guggulu in obesity : data emergent from a naturalistic clinical trial. J Postgrad Med 1995; 41 : 5-7.
22. Drew AK, Myers SP. Safety issues in herbal medicine : Implications for the health professions. Med J Aust 1997; 166 : 538-41.
23. Kozyrskyi A. Herbal products in Canada. How safe are they? Can Fam Physician 1997; 43 : 697-702.
24. Murray CJL, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020 : global burden of disease study. Lancet 1997; 349 : 1498-504.