Prevention of contrast media-induced renal dysfunction with prostaglandin E1: A randomized, double-blind, placebo-controlled study

American Journal of Therapeutics

Volumn 8, Issue 3, 2001, Pages 155-162

  Sketch Jr , Michael H ^a   Whelton, Andrew ^b   Schollmayer, Erwin ^c   Koch, Jens A ^d   Bernink, P J L M ^e   Woltering, Franz ^c   Brinker, Jeffrey ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Schwarz Pharma AG   (Germany)

^d UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^e MARTINI HOSPITAL   (Netherlands)

Author keywords

Contrast media; Nephrotoxicity; Prostaglandins

Indexed keywords

CONTRAST MEDIUM; CREATININE; PROSTAGLANDIN E1;

AGED; ANALYSIS OF VARIANCE; ARTICLE; BLOOD; CHRONIC KIDNEY FAILURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; FEMALE; HUMAN; KIDNEY; MALE; MIDDLE AGED; MULTICENTER STUDY; PILOT STUDY; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL;

AGED; ALPROSTADIL; ANALYSIS OF VARIANCE; CONTRAST MEDIA; CREATININE; DOUBLE-BLIND METHOD; FEMALE; HUMANS; KIDNEY; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; PILOT PROJECTS; PROSPECTIVE STUDIES;

EID: 0035347150     PISSN: 10752765     EISSN: 15363686     Source Type: Journal    
DOI: 10.1097/00045391-200105000-00004     Document Type: Article

References (24)

1. Conlon PJ, Schwab SJ: Time to abandon nonionic contrast? J Am Soc Nephrol 1994;5:123-124.
2. Bresis M, Epstein FH: A closer look at radiocontrast induced nephropathy. N Engl J Med 1989;320:179-181.
3. Parfrey PS, Griffiths SM, Barrett BJ, et al: Contrast material induced renal failure in patients with diabetes mellitus, renal insufficiency or both. N Engl J Med 1989;320:143-149.
4. Barrett BJ, Parfrey PS, Vavsour HM, et al: Contrast nephropathy in patients with impaired renal function: High versus low osmolar media. Kidney Int 1992;41:1274-1279.
5. Tommaso CL: Contrast-induced nephrotoxicity in patients undergoing cardiac catheterization. Catheter Cardiovasc Diagn 1994;31:316-321.
6. Barrett BJ, Carlisle EJ: Metananalysis of the relative nephrotoxicity of high- and low-osmolality iodinated contrast media. Radiology 1993;188:171-178.
7. Barrett BJ, Parfrey PS: Prevention of nephrotoxicity induced by radiocontrast agents. N Engl J Med 1994;331:1449-1450.
8. Rudnick MR, Goldfarb S, Wexler L, et al: Nephrotoxicity of ionic and nonionic contrast media in 1196 patients: A randomized trial. The Iohexed Cooperative Study. Kidney Int 1995;47:254-261.
9. Cronin RE: Radiocontrast media-induced acute renal failure. In: Diseases of the Kidney (Eds. Schrier RW, Gottschalk CW). Little Brown, Boston, 1993, pp1187-1198.
10. Deray G. Nephrotoxicity of contrast media. Nephrol Dial Transplant 1999;14:2602-2606.
11. Deray G, Bellin MF, Boulechfar H, et al: Nephrotoxicity of contrast media in high-risk patients with renal insufficiency: Comparison of low- and high-osmolar contrast agents? Am J Nephrol 1991;11:309-312.
12. Porter GA. Contrast-associated nephropathy: presentation, pathophysiology and management. Miner Electrolyte Metab 1994;20:232-243.
13. Rudnick MR, Berns JS, Cohen RM, et al: Contrast media-associated nephrotoxicity. Curr Opin Nephrol Hypertens 1996;5:127-133.
14. Weisberg, LS, Kurnick PB, Kurnick BR: Risk of radio-contrast nephropathy in patients with and without diabetes mellitus. Kidney Int 1994;45:259-265.
15. Stevens MA, McCullough PA, Tobin KJ: A prospective randomized trial of prevention measures in patients at high risk for contrast nephropathy. J Am Coll Cardiol 1999;33:403-411.
16. Oliveira DBG: Prophylaxis against contrast-induced nephropathy. Lancet 1999;353:1638-1639.
17. Paller MS, Manivel JC: Prostaglandins protect kidneys against ischemic and toxic injury by a cellular effect. Kidney Int 1992;42:1345-1354.
18. Cantley LG, Spokes K, Clark B, et al: Role of endothelin and prostaglandins in radio-contrast induced renal artery constriction. Kidney Int 1993;44:1217-1223.
19. Prins BA, Hu RM, Nazario B: Prostaglandin E1 and prostacyclin inhibit the production and secretion of endothelin from cultured endothelial cells. J Biol Chem 1994;269:11938-11944.
20. Ruetten H, Ney P, Thiemermann C: E-type prostaglandins inhibit the synthesis of endothelin-1 by endothelial cells in culture. Prostagland Leukotr Essent Fatty Acids 1996;55(Suppl 1):123.
21. Erley CM, Duda SH, Rehfuss D, et al: Prevention of radiocontrast-media- induced nephropathy in patients with pre-existing renal insufficiency by hydration in combination with the adenosine antagonist theophylline. Nephrol Dial Transplant 1999;14:1146-1149.
22. Tepel M, Van Der Giet M, Schwarzfeld C, et al: Prevention of radiographic contrast agent induced reductions in renal function by acetylcysteine. N Engl J Med 2000;343:180-184.
23. Levy EM, Viscoli CM, Horwitz RJ: The effect of acute renal failure on mortality. A cohort analysis. JAMA 1996;275:1489-1494.
24. Thiemann D, Tirabassi-Peltzer L, Whelton A, et al: Radiocontrast nephrotoxicity in pre-existing renal impairment: a continuing clinical concern (Abstract Proceedings). Annual Meeting of The Royal College of Physicians and Surgeons of Canada, 1998.