Murine fibromodulin: cDNA and genomic structure, and age-related expression and distribution in the knee joint

Biochemical Journal

Volumn 355, Issue 3, 2001, Pages 577-585

  Säämänen, Anna Marja K ^a   Salminen, Heli J ^a   Rantakokko, A Juho ^a,c   Heinegård, Dick ^b   Vuorio, Eero I ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b LUND UNIVERSITY   (Sweden)

^c ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

Bone; Cartilage; Collagen; Decorin

Indexed keywords

CALCIFICATION (BIOCHEMISTRY); CARTILAGE; COLLAGEN; GENES; RNA;

KNEE-JOINTS;

BIOCHEMISTRY;

COLLAGEN TYPE 1; COLLAGEN TYPE 2; COMPLEMENTARY DNA; DECORIN; FIBROMODULIN; MESSENGER RNA;

AGE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE GROWTH; BONE MATRIX; BONE PLATE; CARTILAGE CELL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EXON; GENE; GENE SEQUENCE; GENE STRUCTURE; KNEE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; OSSIFICATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANIMALIA; MURINAE;

EID: 0035340831     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3550577     Document Type: Article

References (47)

1. 1 Heinegård, D., Larsson, T., Sommarin, Y., Franzen, A., Paulsson, M. and Hedbom, E. (1986) Two novel matrix proteins isolated from articular cartilage show wide distributions among connective tissues. J. Biol. Chem. 261, 13866-13872
2. 2 Hocking, A. M., Shinomura, T. and McQuillan, D. J. (1998) Leucine-rich repeat glycoproteins of the extracellular matrix. Matrix Biol. 17, 1-19
3. 3 Iozzo, R. (1999) The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins. J. Biol. Chem. 274, 18843-18846
4. 4 Reardon, A. J., Le Goff, M., Briggs, M. D., McLeod, D., Sheehan, J. K., Thornton, D. J. and Bishop, P. N. (2000) Identification in vitreous and molecular cloning of opticin, a novel member of the family of leucine-rich repeat proteins of the extracellular matrix. J. Biol. Chem. 275, 2123-2129
5. 5 Wendel, M., Sommarin, Y. and Heinegård, D. (1998) Bone matrix proteins: Isolation and characterization of a novel cell-binding keratan sulfate proteoglycan (osteoadherin) from bovine bone. J. Cell Biol. 141, 839-847
6. 6 Kobe, B. and Deisenhofer, J. (1994) The leucine-rich repeat: a versatile binding motif. Trends Biochem. Sci. 19, 415-421
7. 7 Vogel, K. G., Paulsson, M. and Heinegård, D. (1984) Specific inhibition of type I and type II collagen fibrillogenesis by the small proteoglycan of tendon. Biochem. J. 223, 587-597
8. 8 Hedbom, E. and Heinegård, D. (1989) Interaction of a 59-kDa connective tissue matrix protein with collagen I and collagen II. J. Biol, Chem. 264, 6898-6905
9. 9 Fleischmajer, R., Fisher, L. W., MacDonald, E. D., Jacobs, Jr, L., Perlish, J. S. and Termine, J. D. (1991) Decorin interacts with fibrillar collagen of embryonic and adult human skin. J. Struct. Biol. 106, 82-90
10. 10 Hedbom, E. and Heinegård, D. (1993) Binding of fibromodulin and decorin to separate sites on fibrillar collagens. J. Biol. Chem. 268, 27307-27312
11. 11 Keene, D. R., San Antonio, J. D., Mayne, R., McQuillan, D. J., Sarris, G., Santoro, S. A. and Iozzo, R. V. (2000) Decorin binds near the C-terminus of type I collagen. J. Biol. Chem. 275, 21801-21804
12. 12 Scott, J. E. (1996) Proteodermatan and proteokeratan sulfate (decorin, lumican/fibromodulin) proteins are horseshoe shaped. Implications for their interactions with collagen. Biochemistry 35, 8795-8799
13. 13 Garofalo, S., Metsäranta, M., Ellard, J., Smith, C., Horton, W., Vuorio, E. and de Crombrugghe, B. (1993) Assembly of normal type II collagen in transgenic mice. Proc. Natl. Acad. Sci, U.S.A. 90, 3825-3829
14. 14 Li, S.-W., Prockop, D. J., Helminen, H. J., Fässler, R., Lapveteläinen, T., Kiraly, K., Pelttari, A., Arokoski, J., Lui, H., Arita, M. and Khillan, J. S. (1995) Transgenic mice with targeted inactivation of the Col2a1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone. Genes Dev. 9, 2821-2830
15. 15 Scott, J. E. and Thomlinson, A. M. (1998) The structure of interfibrillar proteoglycan bridges ('shape modules') In extracellular matrix of fibrous connective tissues and their stability in various chemical environments. J. Anat. 192, 391-405
16. 16 Hoshi, K., Kemmotsu, S., Takeuchi, Y., Amizuka, N. and Ozawa, H. (1999) The primary calcification in bones follows removal of decorin and fusion of collagen fibrils. J. Bone Miner. Res. 14, 273-280
17. 17 Svensson, L., Azodi, A., Reinholt, F. P., Fässler, R., Heinegård, D. and Oldberg, Å. (1999) Fibromodulin-null mice have abnormal collagen fibrils, tissue organization, and altered lumican deposition in tendon. J. Biol. Chem. 274, 9636-9647
18. 18 Svensson, L., Narlid, I. and Oldberg, Å. (2000) Fibromodulin and lumican bind to the same region on collagen type I fibrils. FEBS Lett. 470, 178-182
19. 19 Murphy, J. M., Heinegård, D., McIntosh, A., Sterchi, D. and Barry, F. P. (1999) Distribution of cartilage molecules in the developing mouse joint. Matrix Biol. 18, 487-497
20. 20 Chirgwin, J. M., Przybyla, A. E., MacDonald, R. J. and Rutter, W. J. (1979) Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18, 5294-5299
21. 21 Antonsson, P., Heinegård, D. and Oldberg, Å. (1993) Structure and deduced amino acid sequence of the human fibromodulin gene. Biochim. Biophys. Acta 1174, 204-206
22. 22 Hildebrand, A., Romarls, M., Rasmussen, L. M., Heinegård, D., Twardzik, D. R., Border, W. A. and Ruoslahti, E. (1994) Interaction of small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta. Biochem. J. 302, 527-534
23. 23 Oldberg, Å., Antsonsson, P., Lindblom, K. and Heinegård, D. (1989) A collagen binding 59-kd protein (fibromodulin) is structurally related to the small interstitial proteoglycans PG-S1 and PG-S2. EMBO J. 8, 2601-2604
24. 24 Scholzen, T., Solursh, M., Suzuki, S., Reiter, R., Morgan, J. L., Buchberg, A. M., Siracusa, L. D. and Iozzo, R. V.,(1994) Complete cDNA cloning, genomic organization, chromosomal assignment, and expression during organogenesis and tissue differentiation. J. Biol. Chem. 269, 28270-28281
25. 25 Metsäranta, M., Toman, D., de Crombrugghe, B. and Vuorio, E. (1991) Specific hybridization probes for type I, II, III and IX collagen mRNAs. Biochlm. Biophys. Acta 1089, 241-243
26. 26 Iruela-Arispe, M. L., Hasselaar, P. and Sage, H. (1991) Differential expression of extracellular proteins is correlated with angiogenesis in vitro. Lab. Invest. 64, 174-186
27. 27 Sandberg, M. and Vuorio, E. (1987) Localization of types I, II and III collagen mRNAs in developing human skeletal tissues by in situ hybridization. J. Cell Bioi. 104, 1077-1084
28. 28 Ylä-Herttuala, S., Rosenfeld, M. E., Parthasarathy, S., Glass, C. K., Sigal, E., Witztum, J. L. and Steinberg, D. (1990) Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions. Proc. Natl. Acad. Sci. U.S.A. 87, 6959-6963
29. 29 Fisher, L. W., Stubbs, J. T. and Young, M. F. (1995) Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop. Scand. 66, 61-65
30. 30 Strolovics, R., Rimoln, D. L., Rodriguez, E. and Roughley, P. J. (1994) Single-strand conformation polymorphism analysis of human decorin, biglycan and fibromodulin cDNAs. Matrix Biol. 14, 307-312
31. 31 Iozzo, R. and Murdoch, A. D. (1996) Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function. FASEB J. 10, 598-614
32. 32 Iozzo, R. V. (1997) The family of leucine-rich proteoglycans key regulators of matrix assembly and cellular growth. Crit. Rev. Biochem. Mol. Biol. 32, 141-174
33. 33 Iozzo, R. V. (1998) Matrix proteoglycans: from molecular design to cellular function. Annu, Rev. Biochem. 67, 609-652
34. 34 Plaas, A. H., Neame, P. J., Nivens, C. M. and Reiss, L. (1990) Identification of the keratan sulfate attachment sites in bovine fibromodulin. J. Biol. Chem. 265, 20634-20640
35. 35 Graver, J., Chen, X.-N., Korenberg, J. R. and Roughley, P. J. (1995) The human lumican gene. Organization, chromosome location, and expression in articular cartilage. J. Biol. Chem. 270, 21942-21949
36. 36 Grover, J., Chen, X.-N., Korenberg, J. R., Recklies, A. D. and Roughley, P. J. (1996) The gene organization, chromosome location, and expression of 55-kDa matrix protein (PRELP) of human articular cartilage. Genomics 38, 109-117
37. 37 Tasheva, E. S., Funderburgh, J. L., Corpuz, L. M. and Conrad, G. W. (1998) Cloning, characterisation and tissue specific expression of the gene encoding bovine keratocan, a corneal keratan sulfate proteoglycan. Gene 18, 63-68
38. 38 Westergren-Thorsson, G., Antonsson, P., Malmström, A., Heinegård, D. and Oldberg, Å. (1991) The synthesis of a family of structurally related proteoglycans in fibroblasts is differentially regulated by TGF-β. Matrix 11, 177-183
39. 39 Soo, C., Hu, F. Y., Zhang, X., Wang, Y., Beanes, S. R., Lorenz, H. P., Hedrick, M. H., Mackool, R. J., Plaas, A. and Kim, S. J. et al. (2000) Differential expression of fibromodulin, a transforming growth factor-beta modulator, in fetal skin development and scarless repair. Am. J. Pathol. 157, 423-433
40. 40 Hedlund, H., Mengarelli-Widholm, S., Heinegård, D., Reinholt, F. P. and Svensson, O. (1994) Fibromodulin distribution and association with collagen. Matrix Biol. 14, 227-232
41. 41 Chakravarti, S., Magnuson, T., Lass, J. H., Jepsen, K. J., LaMantia, C. and Carrol, H. (1998) Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican. J. Cell Biol. 141, 1277-1286
42. 42 Danielsson, K. G., Baribauit, H., Holmes, D. F., Graham, H., Kadler, K. E. and Iozzo, R. V. (1997) Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility. J. Cell Biol. 136, 729-743
43. 43 Xu, T., Bianco, P., Fisher, L. W., Longenecker, G., Smith, G., Goldstein, S., Bonadio, J., Boskey, A., Heegaard, A.-M. and Sommer, B. et al. (1998) Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice. Nat. Genetics 20, 78-82
44. 44 Roughley, P. J., Melching, L. I. and Recklies, A. D. (1994) Changes in the expression of decorin and biglycan in human articular cartilage with age and regulation by TGF-β. Matrix Biol. 14, 51-59
45. 45 Robbins, J. R. and Vogel, K. G. (1994) Regional expression of mRNA for proteoglycans and collagen in tendon. Eur. J. Cell Biol. 64, 264-270
46. 46 Archer, C. W., Morrison, E. H., Bayliss, M. T. and Ferguson, M. W. (1996) The development of articular cartilage: II. The spatial and temporal patterns of glycosaminoglycans and small leucine-rich proteoglycans. J. Anat. 189, 23-35
47. 47 Blanco, P., Fisher, L. W., Young, M, F., Termine, J. D. and Gehron Robey, P. (1990) Expression and localization of the two small proteoglycans biglycan and decorin in developing human skeletal and non-skeletal tissues. J. Histochem. Cytochem. 38, 1549-1563