The phosphorylated C-terminus of cAR1 plays a role in cell-type-specific gene expression and STATa tyrosine phosphorylation

Developmental Biology

Volumn 233, Issue 1, 2001, Pages 225-236

  Briscoe, Celia ^a   Moniakis, John ^a   Kim, Ji Yun ^b   Brown, Jason M ^a   Hereld, Dale ^c   Devreotes, Peter N ^b   Firtel, Richard A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

cAMP; Dictyostelium; GBF; Gene expression; Receptor; STAT

Indexed keywords

CYCLIC AMP; CYCLIC AMP RECEPTOR; DNA; RNA; STAT PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CELL SPECIFICITY; CELL TYPE; DICTYOSTELIUM; GENE EXPRESSION; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

DICTYOSTELIUM;

EID: 0035337704     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2001.0217     Document Type: Article

References (38)

1. A new class of rapid developing mutants in Dictyostelium discoideum: Implications for cyclic AMP metabolism and cell differentiation
2. Developmentally and spatially regulated activation of a Dictyostelium STAT protein by a serpentine receptor
3. Integration of signaling networks that regulate Dictyostelium differentiation
4. Regulation of cell-fate determination in Dictyostelium
5. Agonist-induced loss of ligand binding is correlated with phosphorylation of cAR1, a G protein-coupled chemoattractant receptor from Dictyostelium
6. Occupancy of the Dictyostelium cAMP receptor, cAR1, induces a reduction in affinity which depends upon COOH-terminal serine residues
7. Signaling through chemoattractant receptors
8. Dimerization of the delta opioid receptor: Implication for a role in receptor internalization
9. G protein-linked signaling pathways control the developmental program of Dictyostelium
10. LagC is required for cell-cell interactions that are essential for cell-type differentiation in Dictyostelium
11. Two distinct populations of prestalk cells within the tip of the migratory Dictyostelium slug with differing fates at culmination
12. Integration of signaling information in controlling cell-fate decisions in Dictyostelium
13. A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation
14. Localization of ligand-induced phosphorylation sites to serine clusters in the C-terminal domain of the Dictyostelium cAMP receptor, cAR1
15. Two cAMP receptors activate common signaling pathways in Dictyostelium
16. Two distinct classes of prestalk-enriched mRNA sequences in Dictyostelium discoideum
17. Evidence that a combined activator-repressor protein regulates Dictyostelium stalk cell differentiation
18. Molecular cloning of casein kinase-II alpha-subunit from Dictyostelium discoideum and its expression in the life cycle
19. Random chimeragenesis of G-protein-coupled receptors: Mapping the affinity of the cAMP chemoattractant receptors in Dictyostelium
20. Phosphorylation of chemoattractant receptors is not essential for chemotaxis or termination of G-protein-mediated responses
21. Switching of chemoattractant receptors programs development and morphogenesis in Dictyostelium: Receptor subtypes activate common responses at different agonist concentrations
22. Genetic networks that regulate development in Dictyostelium cells
23. Seven helix chemoattractant receptors transiently stimulate mitogen-activated protein kinase in Dictyostelium: Role of heterotrimeric G proteins
24. Two-phase regulatory pathway controls cAMP receptor-mediated expression of early genes in Dictyostelium
25. Cyclic AMP regulation of early gene expression in Dictyostelium discoideum: Mediation via the cell surface cyclic AMP receptor
26. A secreted factor and cyclic AMP jointly regulate cell-type-specific gene expression in Dictyostelium discoideum
27. 2+ entry in the absence of functional G proteins in Dictyostelium
28. Evidence that the Dictyostelium Dd-STATa protein is a repressor that regulates commitment to stalk cell differentiation and is also required for efficient chemotaxis
29. G-protein-coupled receptors function as oligomers in vivo
30. The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2
31. The cAMP receptor gene family of Dictyostelium discoideum: Expression, regulation, function
32. Serpentine cAMP receptors may act through a G protein-independent pathway to induce postaggregative development in Dictyostelium
33. Cloning and characterization of the G-box binding factor, an essential component of the developmental switch between early and late development in Dictyostelium
34. Extracellular cAMP can restore development in Dictyostelium cells lacking one, but not two subtypes of early cAMP receptors (cARs). Evidence for involvement of cAR1 in aggregative gene expression
35. Ligand-induced phosphorylation of the cAMP receptor from Dictyostelium discoideum
36. Functional promiscuity of gene regulation by serpentine receptors in Dictyostelium discoideum
37. Morphogenesis in Dictyostelium: New twists to a not-so-old tale
38. Direct induction of Dictyostelium prestalk gene expression by D1F provides evidence that DIF is a morphogen