Relationship between HLA-DRB1 and DQ alleles and the genetic susceptibility to type 1 diabetes

Chinese Medical Journal

Volumn 114, Issue 4, 2001, Pages 407-409

  Sang, Yanmei ^a   Yan, Chun ^a   Zhu, Cheng ^a   Ni, Guichen ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Human leukocyte antigen complex (HLA complex); Type 1 diabetes mellitus

Indexed keywords

HLA DQ ANTIGEN; HLA DR ANTIGEN; HLA-DRB1 ANTIGEN;

ALLELE; ARTICLE; CHILD; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HAPLOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS;

ALLELES; CHILD; DIABETES MELLITUS, TYPE 1; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS;

EID: 0035323045     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Todd JA, Beu JI, McDevitt HO. HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 1987;329:558-563.
2. Khalil J, Lued A, Marcelle G, et al. A combination of HLV-DQβ-Asp 57-negative and HLA-DQα-52-Arg confers susceptibility to insulin dependent diabetes mellitus. J Clin Invest 1990;85: 1315-1319.
3. Gerald TN, William WK. Molecular basis for HLA-DQ association with IDDM. Diabetes 1998;47:1177-1184.
4. Krokowski M, Bodalski J, Bratek A, et al. HLA class II associated predisposition to insulin-dependent diabetes mellitus in a Polish population. Hum Immunol 1998;59:451-457.
5. Huang HS, Peng JT, She JV , et al. HLA-encoded susceptibility to insulin-dependent diabetes mellitus is determined by DR und DQ genes as well as their linkage disequilibria in a Chinese population. Human Immunol 1995;44:210-219.