Synthesis and pharmacological evaluation of aryl/heteroaryl piperazinyl alkyl benzotriazoles as ligands for some serotonin and dopamine receptor subtypes

Farmaco

Volumn 56, Issue 4, 2001, Pages 263-275

  Boido, Alessandro ^a   Canu Boido, Caterina ^a   Sparatore, Fabio ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

Analgesics; Antihypertensives; Antihypoxia agents; Benzotriazole derivatives; Dopamine D2 receptor; Serotonin 5 HT1A receptor

Indexed keywords

1 [3 [4 (3 TRIFLUOROMETHYLPHENYL) 1PIPERAZINYL]PROPYL] 1,2,3 BENZOTRIAZOLE; 2 CHLOROADENOSINE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ADRENALIN; ALPHA 1 ADRENERGIC RECEPTOR; ANALGESIC AGENT; ANGIOTENSIN II [1 SARCOSINE 8 THREONINE]; ANTIHYPERTENSIVE AGENT; ATROPINE; BENZOTRIAZOLE DERIVATIVE; BUSPIRONE; BUTACLAMOL; CAPTOPRIL; CLONIDINE; CROMAKALIM; DEVAZEPIDE; DOPAMINE 2 RECEPTOR; KETANSERIN; LY 17883; NIFEDIPINE; PRAZOSIN; PROPRANOLOL; RECEPTOR SUBTYPE; SEROTONIN 1A RECEPTOR; SPANTIDE; THEOPHYLLINE; TOMELUKAST; TRAZODONE; UNCLASSIFIED DRUG; YOHIMBINE;

ANALGESIC ACTIVITY; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BRAIN HYPOXIA; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; GUINEA PIG; ILEUM CONTRACTION; IN VITRO STUDY; MOUSE; NONHUMAN; RAT; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; TRACHEA PRESSURE;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BEHAVIOR, ANIMAL; DOPAMINE AGENTS; HEART RATE; HEMODYNAMIC PROCESSES; INDICATORS AND REAGENTS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PAIN MEASUREMENT; PIPERAZINES; RECEPTORS, DOPAMINE; RECEPTORS, SEROTONIN; SEROTONIN AGENTS; TRIAZOLES;

EID: 0035305343     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(01)01033-3     Document Type: Article

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