Cytotoxic cyclolignans related to podophyllotoxin

Farmaco

Volumn 56, Issue 4, 2001, Pages 297-304

  Gordaliza, Marina ^a   Miguel Del Corral, José M ^a   Angeles Castro, M ^a   García García, Pablo A ^a   San Feliciano, Arturo ^a  

^a Camp Miguel U   (Spain)

Author keywords

Antineoplastic; Cyclolignans; Cytotoxic; Immunosuppressive; Podophyllotoxin; Pyrazoline

Indexed keywords

ANTIVIRUS AGENT; CYTOTOXIC AGENT; LIGNAN; PODOPHYLLOTOXIN; PODOPHYLLOTOXIN DERIVATIVE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE; VESICULAR STOMATITIS VIRUS;

ALDEHYDES; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DNA TOPOISOMERASES, TYPE II; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HUMANS; LIGNANS; MICE; MOLECULAR CONFORMATION; PODOPHYLLOTOXIN; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0035303594     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(01)01030-8     Document Type: Article

References (40)

1. Ayres D.C., Loike J.D. Lignans. Chemical, Biological and Clinical Properties. 1990;Cambridge University Press, Cambridge. (chaps 3 and 4).
2. (a) R.S. Ward, Nat. Prod. Rep. 16 (1999) 75.
3. (b) Y. Damayanthi, J.W. Lown, Curr. Med. Chem. 5 (1998) 205.
4. (c) I. Jardin, in: J.M. Cassady, J.D. Douros (Eds.), Podophyllotoxins in Anticancer Agents based on Natural Product Models, Academic Press, New York, 1980.
5. (a) C.P. Belani, L.A. Doyle, J. Aisner, Etoposide: current status and future perspectives in the management of malignant neoplasms, Cancer Chemoter. Pharmacol. 34 (Suppl.) (1994) S118.
6. (b) F.M. Muggia, Cancer Chemoter. Pharmacol. 34 (Suppl.) (1994) S127.
7. Witterland A.H., Koks C.H., Beijnen J.H. Pharmacy World Sci. 18:1996;163.
8. Loike J.D., Brewer C.F., Sternlicht H., Gensler W.J., Horwitz S.B. Cancer Res. 38:1978;2688.
9. Loike J.D., Horwitz S.B. Biochemistry. 15:1976;5435.
10. (a) B.H. Long, S.T. Musial, M.B. Brattain, Biochemistry 23 (1984) 1183.
11. (b) R. Ross, T. Rowe, B. Glisson, J. Yalowich, F. Liu, Cancer Res. 44 (1984) 2857.
12. Cho S.J., Kashiwada Y., Bastow K.F., Cheng Y.C., Lee K.H. J. Med. Chem. 39:1996;1396.
13. (a) M.A. Castro, M. Gordaliza, J.M. Miguel del Corral, A. San Feliciano, Phytochemistry 41 (1996) 995.
14. (b) A. San Feliciano, J.M. Miguel del Corral, M. Gordaliza, M.A. Castro, Phytochemistry 28 (1989) 659.
15. (c) A. San Feliciano, J.M. Miguel del Corral, M. Gordaliza, M.A. Castro, Phytochemistry 29 (1990) 1335.
16. (d) A. San Feliciano, J.M. Miguel del Corral, M. Gordaliza, M.A. Castro, Phytochemistry 30 (1991) 3483.
17. San Feliciano A., Miguel del Corral J.M., Gordaliza M., Castro M.A. An. Quim. 88:1992;256.
18. San Feliciano A., Gordaliza M., Miguel del Corral J.M., Castro M.A., García-Grávalos M.D., Ruiz-Lázaro P. Planta Med. 59:1993;246.
19. San Feliciano A., Miguel del Corral J.M., Gordaliza M., Castro M.A. Magn. Reson. Chem. 31:1993;868.
20. Gordaliza M., Castro M.A., García-Grávalos M.D., Ruiz-Lázaro P., Miguel del Corral J.M., San Feliciano A. Arch. Pharm. (Weinheim). 327:1994;175.
21. Castro M.A., Gordaliza M., Miguel del Corral J.M., San Feliciano A. Org. Prep. Proced. Int. 26:1994;539.
22. Gordaliza M., Miguel del Corral J.M., Castro M.A., López-Vázquez M.L., García P.A., San Feliciano A., García-Grávalos M.D. Bioorg. Med. Chem. Lett. 5:1995;2465.
23. Gordaliza M., Miguel del Corral J.M., Castro M.A., López-Vázquez M.L., San Feliciano A., García-Grávalos A. M.D., Carpy A. Bioorg. Med. Chem. 3:1995;1203.
24. Miguel del Corral J.M., Gordaliza M., Castro M.A., Morales L.J., López J.L., San Feliciano A. J. Nat. Prod. 58:1995;870.
25. Miguel del Corral J.M., Gordaliza M., López J.L., del Olmo E., Castro M.A., López-Vázquez M.L. Helv. Chim. Acta. 78:1995;1793.
26. M. Gordaliza, M.A. Castro, A. San Feliciano, J.M. Miguel del Corral, M.L. López-Vazquez, G.T. Faircloth, Patent EP 711765 A1.
27. M. Gordaliza, M.A. Castro, A. San Feliciano, J.M. Miguel del Corral, M.L López-Vazquez, M.L. García-Grávalos, Patent EP 711767 A1.
28. Doré J.C., Viel C., Pageot N., Gordaliza M., Castro M.A., Miguel del Corral J.M., San Feliciano A. J. Pharm. Belg. 51:1996;9.
29. Gordaliza M., Faircloth G.T., Castro M.A., Miguel del Corral J.M., López-Vázquez M.L., San Feliciano A. J. Med. Chem. 39:1996;2865.
30. Miguel del Corral J.M., Gordaliza M., Castro M.A., García-Grávalos M.D., Broughton H.B., San Feliciano A. Tetrahedron. 53:1997;6555.
31. Gordaliza M., Castro M.A., Miguel del Corral J.M., San Feliciano A., Faircloth G.T. Bioorg. Med. Chem. Lett. 7:1997;2781.
32. Gordaliza M., Castro M.A., Miguel del Corral J.M., López-Vazquez M.L., García- García P.A., San Feliciano A., García-Grávalos M.D., Broughton H. Tetrahedron. 53:1997;15743.
33. Castro M.A., Miguel del Corral J.M., López-Vazquez M.L., García-García P.A., San Felliciano A., Gordaliza M. Magn. Reson. Chem. 35:1997;808.
34. Gordaliza M., Castro M.A., Miguel del Corral J.M., San Feliciano A. Curr. Pharm. Design. 6:2000;1807.
35. Broughton H.B., Gordaliza M., Castro M.A., Miguel del Corral J.M., San Feliciano A. Theochem. 504:2000;287.
36. Gordaliza M., Castro M.A., Miguel del Corral J.M., López-Vazquez M.L., García-García P.A., García-Graválos M.D., San Feliciano A. Eur. J. Med. Chem. 35:2000;691.
37. Bergeron R.J., Cavanagh P.F Jr., Kline S.J., Hughes R.G., Elliot G.T., Porter C.W. Biochem. Biophys. Res. Commun. 3:1984;121.
38. Haar E., Rosenkranz H.S., Hamel E., Day B.W. Bioorg. Med. Chem. 4:1996;1659.
39. Mac Donald T.L., Lehnert E.K., Loper J.T., Chow K.C., Ross W.E. Potmensil M., Kohn K.W. DNA Topoisomerase in Cancer. 1992;Oxford University Press, New York.
40. Eich E., Schulz J., Kaloga M., Merz H., Schoder H.C., Muller W.E.G. Planta Med. 57:(Suppl. 2):1991;7.