Dynamic nuclear localization of the baculovirus proteins IE2 and PE38 during the infection cycle: The promyelocytic leukemia protein colocalizes with IE2

Experimental Cell Research

Volumn 264, Issue 2, 2001, Pages 219-232

  Murges, Daniela ^a   Quadt, Ilja ^a   Schröer, Jörg ^a   Knebel Mörsdorf, Dagmar ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Ac MNPV recombinant; Baculovirus; Colocalization; IE2; Nuclear distribution; Nuclear domains; PE38; PML; POD; TN 368 cells

Indexed keywords

CELL PROTEIN; IMMEDIATELY EARLY PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS PROTEIN IE2; VIRUS PROTEIN PE38;

ARTICLE; BACULOVIRUS; CELL NUCLEUS INCLUSION BODY; CONTROLLED STUDY; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; INSECT; MAMMAL CELL; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN DOMAIN; PROTEIN LOCALIZATION; VIRUS RECOMBINANT;

EID: 0035298136     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2000.5081     Document Type: Article

References (46)

1. Nuclear bodies: Multifaceted subdomains of the interchromatin space
2. Nuclear dots: Actors on many stages
3. Structure, organization and dynamics of promyelocytic leukemia protein nuclear bodies
4. Nuclear domain 10, the site of DNA virus transcription and replication
5. The PML-RAR alpha fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
6. Characterization of a zinc finger gene disrupted by the t(15;17) in acute promyelocytic leukemia
7. Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML
8. HSV-1 IE protein Vmw110 causes redistribution of PML
9. The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms
10. 4 finger family, during baculovirus infection: PE38 and IE2 localize to distinct nuclear regions
11. Functional mapping of an AcNPV immediate early gene which augments expression of the IE-1 trans-activated 39K gene
12. Identification of the very early transcribed baculovirus gene PE38
13. Functional dissection of the ie2 gene product of the baculovirus Autographa californica nuclear polyhedrosis virus
14. The Autographa californica nuclear polyhedrosis virus ie2 gene encodes a transcriptional regulator
15. Three baculovirus genes involved in late and very late gene expression: ie-1, ie-n, and lef-2
16. The roles of eighteen baculovirus late expression factor genes in transcription and DNA replication
17. Role of baculovirus IE2 and its RING finger in cell cycle arrest
18. In vivo and in vitro analysis of baculovirus ie-2 mutants
19. Immediate-early baculovirus genes transactivate the p143 gene promoter of Autographa californica nuclear polyhedrosis virus
20. Identification of genes involved in DNA replication of Autographa californica baculovirus
21. The baculovirus PE38 protein augments apoptosis induced by transactivator IE1
22. A novel cysteine-rich sequence motif
23. Identification and preliminary characterization of a protein motif related to the zinc finger
24. Studies on the mechanism of poliovirus-induced cell damage. I. The relation between poliovirus-induced metabolic and morphological alterations
25. The establishment of two cell lines from the insect Spodoptera frugiperda
26. Established insect cell line from the cabbage looper, Trichoplusia ni
27. Two tissue culture media for production of lepidopteran cells and nuclear polyhedrosis viruses
28. Infection of Spodoptera frugiperda cells with Autographa californica nuclear polyhedrosis virus. II. The viral DNA and the kinetics of its replication
29. Functional analysis of a 603 nucleotide open reading frame upstream of the polyhedrin gene of Autographa californica nuclear polyhedrosis virus
30. Baculovirus infection of Spodoptera exigua larvae: LacZ expression driven by promoters of early genes pe38 and me53 in larval tissue
31. Different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positions
32. Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells
33. A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies
34. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4
35. Requirements for nuclear localization and supramolecular assembly of a baculovirus polyhedrin protein
36. The complete DNA sequence of Autographa californica nuclear polyhedrosis virus
37. Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies
38. Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure
39. The adenovirus type 5 E1b 55K and E4Orf3 proteins associate in infected cells and affect ND10 components
40. A novel macromolecular structure is a target of the promyelocytic-retinoic acid receptor oncoprotein
41. Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0)
42. Disruption of PML-associated nuclear bodies during human cytomegalovirus infection
43. The major immediate-early proteins IE1 and IE2 of human cytomegalovirus colocalize with and disrupt PML-associated nuclear bodies at very early times in infected permissive cells
44. The nuclear domain 10 (ND10) is disrupted by the human cytomegalovirus gene product IE1
45. The periphery of nuclear domain 10 (ND10) as site of DNA virus deposition
46. Colocalization of baculovirus IE-1 and two DNA-binding proteins DBP and LEF-3, to viral replication factories