-
1
-
-
0033611522
-
Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide
-
PID: 9920950, COI: 1:CAS:528:DyaK1MXht1WqsbY%3D
-
Turrisi A, Kim K, Blum R, et al.: Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide. N Engl J Med 1999, 340:265–271. DOI: 10.1056/NEJM199901283400403
-
(1999)
N Engl J Med
, vol.340
, pp. 265-271
-
-
Turrisi, A.1
Kim, K.2
Blum, R.3
-
2
-
-
0025898914
-
Randomized trial of cyclophosphamide, doxorubicin, and vincristine versus cisplatin and etoposide versus alternation of these regimens in small-cell lung cancer
-
PID: 1648142, COI: 1:STN:280:DyaK3M3oslWgtw%3D%3D
-
Fukuoka M, Furuse K, Saijo N, et al.: Randomized trial of cyclophosphamide, doxorubicin, and vincristine versus cisplatin and etoposide versus alternation of these regimens in small-cell lung cancer. J Natl Cancer Inst 1991, 83:855–861. DOI: 10.1093/jnci/83.12.855
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 855-861
-
-
Fukuoka, M.1
Furuse, K.2
Saijo, N.3
-
3
-
-
0018374180
-
Small cell lung cancer: complete remission and improved survival
-
PID: 219690, COI: 1:STN:280:DyaE1M7mt1Oguw%3D%3D
-
Greco FA, Richardson RL, Snell JD, et al.: Small cell lung cancer: complete remission and improved survival. Am J Med 1979, 66:625–630. DOI: 10.1016/0002-9343(79)91173-2
-
(1979)
Am J Med
, vol.66
, pp. 625-630
-
-
Greco, F.A.1
Richardson, R.L.2
Snell, J.D.3
-
4
-
-
0027447420
-
The current status of camptothecin analogues as antitumor agents
-
PID: 8381186, COI: 1:CAS:528:DyaK3sXit1CksL0%3D
-
Slichenmyer WJ, Rowinsky EK, Donehower RC, et al.: The current status of camptothecin analogues as antitumor agents. J Natl Cancer Inst 1993, 85:271–291. DOI: 10.1093/jnci/85.4.271
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 271-291
-
-
Slichenmyer, W.J.1
Rowinsky, E.K.2
Donehower, R.C.3
-
5
-
-
0027972726
-
Topoisomerase I inhibitors: topotecan and irinotecan
-
Creemerst GJ, Lund B, Verweij J: Topoisomerase I inhibitors: topotecan and irinotecan. Cancer Treat Rev 1994, 20:73–96. DOI: 10.1016/0305-7372(94)90011-6
-
(1994)
Cancer Treat Rev
, vol.20
, pp. 73-96
-
-
Creemerst, G.J.1
Lund, B.2
Verweij, J.3
-
6
-
-
0030055094
-
Current perspectives on camptothecins in cancer treatment
-
PID: 8695345, COI: 1:CAS:528:DyaK28XltlaitL4%3D
-
Dancey J, Eisenhauer EA: Current perspectives on camptothecins in cancer treatment. Br J Cancer 1996, 74:327–338.
-
(1996)
Br J Cancer
, vol.74
, pp. 327-338
-
-
Dancey, J.1
Eisenhauer, E.A.2
-
7
-
-
0025272187
-
Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse
-
PID: 2306725, COI: 1:CAS:528:DyaK3cXitFSnurk%3D
-
Kaneda N, Nagata H, Furuta T, et al.: Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse. Cancer Res 1990, 50:1715–1720.
-
(1990)
Cancer Res
, vol.50
, pp. 1715-1720
-
-
Kaneda, N.1
Nagata, H.2
Furuta, T.3
-
8
-
-
0025996996
-
Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, the antitumor effect of CPT-11
-
PID: 1651156, COI: 1:CAS:528:DyaK3MXlsV2rurs%3D
-
Kawato Y, Aonuma M, Hirota Y, et al.: Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, the antitumor effect of CPT-11. Cancer Res 1991, 51:4187–4191.
-
(1991)
Cancer Res
, vol.51
, pp. 4187-4191
-
-
Kawato, Y.1
Aonuma, M.2
Hirota, Y.3
-
9
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial
-
PID: 10744089, COI: 1:CAS:528:DC%2BD3cXisFOnsb4%3D
-
Douillard JY, Cunningham D, Roth AD, et al.: Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 2000, 355:1041–1047. DOI: 10.1016/S0140-6736(00)02034-1
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
-
10
-
-
0032585232
-
Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer
-
PID: 9807987, COI: 1:CAS:528:DyaK1cXnsVSmsLs%3D
-
Cunningham D, Pyrhonen S, James RD, et al.: Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer. Lancet 1998, 352:1413–1418. DOI: 10.1016/S0140-6736(98)02309-5
-
(1998)
Lancet
, vol.352
, pp. 1413-1418
-
-
Cunningham, D.1
Pyrhonen, S.2
James, R.D.3
-
11
-
-
0032585197
-
Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer
-
PID: 9807986, COI: 1:CAS:528:DyaK1cXnsVSmsLo%3D
-
Rougier P, Van Cutsem E, Bajetta E: Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer. Lancet 1998, 352:1407–1412. DOI: 10.1016/S0140-6736(98)03085-2
-
(1998)
Lancet
, vol.352
, pp. 1407-1412
-
-
Rougier, P.1
Van Cutsem, E.2
Bajetta, E.3
-
12
-
-
0000575486
-
Randomized phase III study of irinotecan (CPT-11) and cisplatin versus etoposide and cisplatin in extensive-disease small-cell lung cancer: Japan Clinical Oncology Group study (JCOG9511) [abstract]
-
This phase III study demonstrated that treatment with four cycles of irinotecan plus cisplatin every 4 weeks yielded a highly significant improvement survival over standard etoposide plus cisplatin, with less myelosuppression, patients with extensive-disease small-cell lung cancer
-
Noda K, Nishiwaki Y, Kawahara M, et al.: Randomized phase III study of irinotecan (CPT-11) and cisplatin versus etoposide and cisplatin in extensive-disease small-cell lung cancer: Japan Clinical Oncology Group study (JCOG9511) [abstract]. Proc ASCO 2000, 19:483a. This phase III study demonstrated that treatment with four cycles of irinotecan plus cisplatin every 4 weeks yielded a highly significant improvement in survival over standard etoposide plus cisplatin, with less myelosuppression, in patients with extensive-disease small-cell lung cancer.
-
(2000)
Proc ASCO
, vol.19
, pp. 483a
-
-
Noda, K.1
Nishiwaki, Y.2
Kawahara, M.3
-
13
-
-
0028931509
-
Novel antitumor indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (NB-506): induction of topoisomerase I-mediated DNA cleavage and mechanisms of cell line-selective cytotoxicity
-
PID: 7882328, COI: 1:STN:280:DyaK2M7ovVWltw%3D%3D
-
Yoshinari T, Matsumoto M, Arakawa H, et al.: Novel antitumor indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (NB-506): induction of topoisomerase I-mediated DNA cleavage and mechanisms of cell line-selective cytotoxicity. Cancer Res 1995, 55:1310–1315.
-
(1995)
Cancer Res
, vol.55
, pp. 1310-1315
-
-
Yoshinari, T.1
Matsumoto, M.2
Arakawa, H.3
-
14
-
-
0028905348
-
Novel indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo-[3,4c]carbazole-5,7(6H)-dione (NB-506): its potent antitumor activities in mice
-
PID: 7882329, COI: 1:CAS:528:DyaK2MXktlKmt7w%3D
-
Arakawa H, Iguchi T, Morita M, et al.: Novel indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo-[3,4c]carbazole-5,7(6H)-dione (NB-506): its potent antitumor activities in mice. Cancer Res 1995, 55:1316–1320.
-
(1995)
Cancer Res
, vol.55
, pp. 1316-1320
-
-
Arakawa, H.1
Iguchi, T.2
Morita, M.3
-
15
-
-
0003267271
-
Phase I and pharmacology study of 5-day infusion of NB-506 [abstract]
-
Ohe Y, Tanigawara Y, Fujii H, et al.: Phase I and pharmacology study of 5-day infusion of NB-506 [abstract]. Proc ASCO 1997, 16:199a.
-
(1997)
Proc ASCO
, vol.16
, pp. 199a
-
-
Ohe, Y.1
Tanigawara, Y.2
Fujii, H.3
-
16
-
-
0032702777
-
In vivo anti-tumor activity of a novel indolocarbazole compound, J-107088, on murine and human tumors transplanted into mice
-
PID: 10595746, COI: 1:CAS:528:DyaK1MXotFaqsr0%3D
-
Arakawa H, Morita M, Kodera T, et al.: In vivo anti-tumor activity of a novel indolocarbazole compound, J-107088, on murine and human tumors transplanted into mice. Jpn J Cancer Res 1999, 90:1163–1170.
-
(1999)
Jpn J Cancer Res
, vol.90
, pp. 1163-1170
-
-
Arakawa, H.1
Morita, M.2
Kodera, T.3
-
17
-
-
0033199091
-
Mode of action of new indolocarbazole anticancer agent, J-107088, targeting topoisomerase I
-
PID: 10485471, COI: 1:CAS:528:DyaK1MXlvVSms74%3D
-
Yoshinari T, Ohkubo M, Fukasawa K, et al.: Mode of action of new indolocarbazole anticancer agent, J-107088, targeting topoisomerase I. Cancer Res 1999, 59:4271–4275.
-
(1999)
Cancer Res
, vol.59
, pp. 4271-4275
-
-
Yoshinari, T.1
Ohkubo, M.2
Fukasawa, K.3
-
18
-
-
0025851286
-
Phase I study of weekly intravenous infusions of CPT-11, a new derivative of camptothecin, in the treatment of advanced non-small-cell lung cancer
-
PID: 1653362, COI: 1:STN:280:DyaK3MzlvFeguw%3D%3D
-
Negoro S, Fukuoka M, Masuda N, et al.: Phase I study of weekly intravenous infusions of CPT-11, a new derivative of camptothecin, in the treatment of advanced non-small-cell lung cancer. J Natl Cancer Inst 1991, 83:1164–1168. DOI: 10.1093/jnci/83.16.1164
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 1164-1168
-
-
Negoro, S.1
Fukuoka, M.2
Masuda, N.3
-
19
-
-
0026631164
-
Phase I study and pharmacokinetics of CPT-11 with 5-day continuous infusion
-
PID: 1321253, COI: 1:STN:280:DyaK38zjtlGqsQ%3D%3D
-
Ohe Y, Sasaki Y, Shinkai T, et al.: Phase I study and pharmacokinetics of CPT-11 with 5-day continuous infusion. J Natl Cancer Inst 1992, 84:972–974. DOI: 10.1093/jnci/84.12.972
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 972-974
-
-
Ohe, Y.1
Sasaki, Y.2
Shinkai, T.3
-
20
-
-
0028854897
-
Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients
-
PID: 7799022, COI: 1:STN:280:DyaK2M%2Fps12nug%3D%3D
-
Abigerges D, Chabot GG, Armand JP, et al.: Phase I and pharmacologic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients. J Clin Oncol 1995, 13:210–221.
-
(1995)
J Clin Oncol
, vol.13
, pp. 210-221
-
-
Abigerges, D.1
Chabot, G.G.2
Armand, J.P.3
-
21
-
-
0027140524
-
Phase I and pharmacokinetic trial of weekly CPT-11
-
PID: 8229134, COI: 1:STN:280:DyaK2c%2FksFyhtw%3D%3D
-
Rothenberg ML, Kuhn JG, Burris HA, et al.: Phase I and pharmacokinetic trial of weekly CPT-11. J Clin Oncol 1993, 11:2194–2204.
-
(1993)
J Clin Oncol
, vol.11
, pp. 2194-2204
-
-
Rothenberg, M.L.1
Kuhn, J.G.2
Burris, H.A.3
-
22
-
-
0000271228
-
Phase II study of irinotecan (CPT-11) in patients with previously treated small-cell lung cancer (SCLC) [abstract]
-
DeVore RF, Blanke CD, Denharm CA, et al.: Phase II study of irinotecan (CPT-11) in patients with previously treated small-cell lung cancer (SCLC) [abstract]. Proc ASCO 1998, 17:451a.
-
(1998)
Proc ASCO
, vol.17
, pp. 451a
-
-
DeVore, R.F.1
Blanke, C.D.2
Denharm, C.A.3
-
23
-
-
0026537874
-
Phase I and pharmacologic study of topotecan: a novel topoisomerase I inhibitor
-
PID: 1312588, COI: 1:STN:280:DyaK387ptl2ktQ%3D%3D
-
Rowinsky EK, Grochow LB, Hendricks CB, et al.: Phase I and pharmacologic study of topotecan: a novel topoisomerase I inhibitor. J Clin Oncol 1992, 10:647–656.
-
(1992)
J Clin Oncol
, vol.10
, pp. 647-656
-
-
Rowinsky, E.K.1
Grochow, L.B.2
Hendricks, C.B.3
-
24
-
-
26344458583
-
Oral topotecan (OT) as single-agent first-line treatment for patients with extensive disease (ED) small cell lung cancer (SCLC) ineligible for standard therapy: a phase II study [abstract]
-
Eckardt J, Palmer MC, Fanucchi M, et al.: Oral topotecan (OT) as single-agent first-line treatment for patients with extensive disease (ED) small cell lung cancer (SCLC) ineligible for standard therapy: a phase II study [abstract]. Proc ASCO 2000, 19:494a.
-
(2000)
Proc ASCO
, vol.19
, pp. 494a
-
-
Eckardt, J.1
Palmer, M.C.2
Fanucchi, M.3
-
25
-
-
15644373056
-
Phase I and pharmacokinetic study of GI147211, a water-soluble camptothecin analogue, administered for five consecutive days every three weeks
-
PID: 9533526, COI: 1:CAS:528:DyaK1cXit1aquro%3D
-
Eckhardt SG, Baker SD, Eckardt JR, et al.: Phase I and pharmacokinetic study of GI147211, a water-soluble camptothecin analogue, administered for five consecutive days every three weeks. Clin Cancer Res 1998, 4:595–604.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 595-604
-
-
Eckhardt, S.G.1
Baker, S.D.2
Eckardt, J.R.3
-
26
-
-
0029928849
-
Phase I and pharmacological study of the new topoisomerase I inhibitor GI147211, using a daily x 5 intravenous administration
-
PID: 8611374, COI: 1:CAS:528:DyaK28Xitl2nsL8%3D
-
Gerrits CJ, Creemers GJ, Schellens JH, et al.: Phase I and pharmacological study of the new topoisomerase I inhibitor GI147211, using a daily x 5 intravenous administration. Br J Cancer 1996, 73:744–750.
-
(1996)
Br J Cancer
, vol.73
, pp. 744-750
-
-
Gerrits, C.J.1
Creemers, G.J.2
Schellens, J.H.3
-
27
-
-
0034066518
-
Second-line treatment of small-cell lung cancer with the camptothecin-derivative GI147211: a study of the EORTC Early Clinical Studies Group (ECSG)
-
PID: 10761757, COI: 1:STN:280:DC%2BD3c3it1eqtg%3D%3D, The EORTC demonstrated activity with the new topoisomerase I inhibitor GG211 as a second-line treatment of SCLC
-
Sessa C, Wanders J, Roelvink M, et al.: Second-line treatment of small-cell lung cancer with the camptothecin-derivative GI147211: a study of the EORTC Early Clinical Studies Group (ECSG). Ann Oncol 2000, 11:207–210. The EORTC demonstrated activity with the new topoisomerase I inhibitor GG211 as a second-line treatment of SCLC. DOI: 10.1023/A:1008372404504
-
(2000)
Ann Oncol
, vol.11
, pp. 207-210
-
-
Sessa, C.1
Wanders, J.2
Roelvink, M.3
-
28
-
-
0000107302
-
Phase II study of CPT-11, new camptothecin derivative, in small cell lung cancer (SCLC) [abstract]
-
Negoro S, Fukuoka M, Niitani H, et al.: Phase II study of CPT-11, new camptothecin derivative, in small cell lung cancer (SCLC) [abstract]. Proc ASCO 1991, 10:241.
-
(1991)
Proc ASCO
, vol.10
, pp. 241
-
-
Negoro, S.1
Fukuoka, M.2
Niitani, H.3
-
29
-
-
0026680292
-
CPT-11: a new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer
-
PID: 1321891, COI: 1:STN:280:DyaK38zktFWgtA%3D%3D
-
Masuda N, Fukuoka M, Kusunoki Y, et al.: CPT-11: a new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer. J Clin Oncol 1992, 10:1225–1229.
-
(1992)
J Clin Oncol
, vol.10
, pp. 1225-1229
-
-
Masuda, N.1
Fukuoka, M.2
Kusunoki, Y.3
-
30
-
-
0029790139
-
Phase II study of topotecan in patients with extensive-stage small-cell carcinoma of the lung: an Eastern Cooperative Oncology Group Trial
-
PID: 8708727, COI: 1:CAS:528:DyaK28XltFSqtr8%3D
-
Schiller JH, Kim K, Hutson P, et al.: Phase II study of topotecan in patients with extensive-stage small-cell carcinoma of the lung: an Eastern Cooperative Oncology Group Trial. J Clin Oncol 1996, 14:2345–2352.
-
(1996)
J Clin Oncol
, vol.14
, pp. 2345-2352
-
-
Schiller, J.H.1
Kim, K.2
Hutson, P.3
-
31
-
-
0029758947
-
Treatment of patients with small-cell lung cancer refractory to etoposide and cisplatin with the topoisomerase I poison topotecan
-
PID: 8874340, COI: 1:CAS:528:DyaK28XmsFCgt7o%3D
-
Perez-Soler R, Glisson BS, Lee JS, et al.: Treatment of patients with small-cell lung cancer refractory to etoposide and cisplatin with the topoisomerase I poison topotecan. J Clin Oncol 1996, 14:2785–2790.
-
(1996)
J Clin Oncol
, vol.14
, pp. 2785-2790
-
-
Perez-Soler, R.1
Glisson, B.S.2
Lee, J.S.3
-
32
-
-
0030913459
-
Topotecan, a new active drug in the second-line treatment of small-cell lung cancer: a phase II study in patients with refractory and sensitive disease. The European Organization for Research and Treatment of Cancer Early Clinical Studies Group and New Drug Development Office, and the Lung Cancer Cooperative Group
-
PID: 9164222, COI: 1:CAS:528:DyaK2sXjsVCrtLg%3D
-
Ardizzoni A, Hansen H, Dombernowsky P, et al.: Topotecan, a new active drug in the second-line treatment of small-cell lung cancer: a phase II study in patients with refractory and sensitive disease. The European Organization for Research and Treatment of Cancer Early Clinical Studies Group and New Drug Development Office, and the Lung Cancer Cooperative Group. J Clin Oncol 1997, 15:2090–2096.
-
(1997)
J Clin Oncol
, vol.15
, pp. 2090-2096
-
-
Ardizzoni, A.1
Hansen, H.2
Dombernowsky, P.3
-
33
-
-
0027479925
-
Enhanced antitumor efficacy of a combination of CPT-11, a new derivative of camptothecin, and cisplatin against human lung tumor xenografts
-
PID: 8385085, COI: 1:CAS:528:DyaK3sXhvVaqsb0%3D
-
Kudoh S, Takada M, Masuda N, et al.: Enhanced antitumor efficacy of a combination of CPT-11, a new derivative of camptothecin, and cisplatin against human lung tumor xenografts. Jpn J Cancer Res 1993, 84:203–207.
-
(1993)
Jpn J Cancer Res
, vol.84
, pp. 203-207
-
-
Kudoh, S.1
Takada, M.2
Masuda, N.3
-
34
-
-
0031887545
-
Phase II study of irinotecan combined with cisplatin in patients with previously untreated small-cell lung cancer
-
PID: 9508192, COI: 1:CAS:528:DyaK1cXitVKitrs%3D, Report of very encouraging results with irinotecan plus cisplatin, especially for patients with ED-SCLC. Based on this study, the JCOG conducted a phase III study of cisplatin plus irinotecan versus cisplatin plus etoposide for untreated ED-SCLC (JCOG9511
-
Kudoh S, Fujiwara Y, Takada Y, et al.: Phase II study of irinotecan combined with cisplatin in patients with previously untreated small-cell lung cancer. J Clin Oncol 1998, 16:1068–1074. Report of very encouraging results with irinotecan plus cisplatin, especially for patients with ED-SCLC. Based on this study, the JCOG conducted a phase III study of cisplatin plus irinotecan versus cisplatin plus etoposide for untreated ED-SCLC (JCOG9511).
-
(1998)
J Clin Oncol
, vol.16
, pp. 1068-1074
-
-
Kudoh, S.1
Fujiwara, Y.2
Takada, Y.3
-
35
-
-
0026600884
-
Experimental studies on biochemical modulation targeting topoisomerase I and II in human tumor xenografts in nude mice
-
PID: 1312063, COI: 1:CAS:528:DyaK38XisVOqu78%3D
-
Kim R, Hirabayashi N, Nishiyama M, et al.: Experimental studies on biochemical modulation targeting topoisomerase I and II in human tumor xenografts in nude mice. Int J Cancer 1992, 50:760–766. DOI: 10.1002/ijc.2910500516
-
(1992)
Int J Cancer
, vol.50
, pp. 760-766
-
-
Kim, R.1
Hirabayashi, N.2
Nishiyama, M.3
-
36
-
-
0031725727
-
Combination of irinotecan and etoposide for treatment of refractory or relapsed small-cell lung cancer
-
PID: 9779709, COI: 1:CAS:528:DyaK1cXmvFGrtbs%3D, a study of combination chemotherapy with irinotecan and etoposide for refractory and relapsed SCLC, a 71% overall response rate and 271-day MST were reported
-
Masuda N, Matsui K, Negoro S, et al.: Combination of irinotecan and etoposide for treatment of refractory or relapsed small-cell lung cancer. J Clin Oncol 1998, 16:3329–3334. In a study of combination chemotherapy with irinotecan and etoposide for refractory and relapsed SCLC, a 71% overall response rate and 271-day MST were reported.
-
(1998)
J Clin Oncol
, vol.16
, pp. 3329-3334
-
-
Masuda, N.1
Matsui, K.2
Negoro, S.3
-
37
-
-
0000678949
-
Phase II study of irinotecan (CPT-11) combined with etoposide (VP-16) for previously untreated extensive-disease small cell lung cancer (ED-SCLC): a study of the West Japan Lung Cancer Group [abstract]
-
Nakamura S, Kudoh S, Komuta K, et al.: Phase II study of irinotecan (CPT-11) combined with etoposide (VP-16) for previously untreated extensive-disease small cell lung cancer (ED-SCLC): a study of the West Japan Lung Cancer Group [abstract]. Proc ASCO 1999, 18:470a.
-
(1999)
Proc ASCO
, vol.18
, pp. 470a
-
-
Nakamura, S.1
Kudoh, S.2
Komuta, K.3
-
38
-
-
0003210160
-
Combination chemotherapy with cisplatin and topotecan as second-line treatment of sensitive (S) and refractory (R) small cell lung cancer (SCLC): an EORTC LCCG phase II study [abstract]
-
Ardizzoni A, Manegold C, Gaafar R, et al.: Combination chemotherapy with cisplatin and topotecan as second-line treatment of sensitive (S) and refractory (R) small cell lung cancer (SCLC): an EORTC LCCG phase II study [abstract]. Proc ASCO 1999, 18:471a.
-
(1999)
Proc ASCO
, vol.18
, pp. 471a
-
-
Ardizzoni, A.1
Manegold, C.2
Gaafar, R.3
-
39
-
-
0029993118
-
Treatment-related fatal sepsis from topotecan/cisplatin and topotecan/paclitaxel
-
PID: 8656268, COI: 1:CAS:528:DyaK28Xkt1WksL0%3D
-
Miller AA, Lilenbaum RC, Lynch TJ, et al.: Treatment-related fatal sepsis from topotecan/cisplatin and topotecan/paclitaxel. J Clin Oncol 1996, 14:1964–1965.
-
(1996)
J Clin Oncol
, vol.14
, pp. 1964-1965
-
-
Miller, A.A.1
Lilenbaum, R.C.2
Lynch, T.J.3
-
40
-
-
0003293064
-
Paclitaxel (P) + topotecan (T) + GCSF for previously untreated extensive small cell lung cancer (E-SCLC): preliminary analysis of Cancer and Leukemia Group B (CALGB) 9430 [abstract]
-
Lynch T, Herndon J, Lyss A, et al.: Paclitaxel (P) + topotecan (T) + GCSF for previously untreated extensive small cell lung cancer (E-SCLC): preliminary analysis of Cancer and Leukemia Group B (CALGB) 9430 [abstract]. Proc ASCO 2000, 19:491a.
-
(2000)
Proc ASCO
, vol.19
, pp. 491a
-
-
Lynch, T.1
Herndon, J.2
Lyss, A.3
-
41
-
-
0001285863
-
Paclitaxel, carboplatin, and topotecan in the treatment of small cell lung cancer: a phase II trial of the Minnie Pearl Cancer Research Network [abstract]
-
Gray J, Hainsworth J, Burris H, et al.: Paclitaxel, carboplatin, and topotecan in the treatment of small cell lung cancer: a phase II trial of the Minnie Pearl Cancer Research Network [abstract]. Proc ASCO 2000, 19:494a.
-
(2000)
Proc ASCO
, vol.19
, pp. 494a
-
-
Gray, J.1
Hainsworth, J.2
Burris, H.3
-
42
-
-
0004701590
-
Phase II trial of topotecan and paclitaxel (TP) with G-CSF support alternating with etoposide and cisplatin (EC) in previously untreated extensive stage small cell lung cancer (ED-SCLC) [abstract]
-
Jett J, Hatfield A, Bauman M, et al.: Phase II trial of topotecan and paclitaxel (TP) with G-CSF support alternating with etoposide and cisplatin (EC) in previously untreated extensive stage small cell lung cancer (ED-SCLC) [abstract]. Proc ASCO 2000, 19:491a.
-
(2000)
Proc ASCO
, vol.19
, pp. 491a
-
-
Jett, J.1
Hatfield, A.2
Bauman, M.3
-
43
-
-
4243870956
-
Weekly cisplatin-paclitaxeltopotecan (CPT) as front-line therapy for extensive disease small cell lung cancer (ED-SCLC): a Southern Italy Cooperative Oncology Group (SICOG) phase II study [abstract]
-
Panza N, Frasci G, Comella P, et al.: Weekly cisplatin-paclitaxeltopotecan (CPT) as front-line therapy for extensive disease small cell lung cancer (ED-SCLC): a Southern Italy Cooperative Oncology Group (SICOG) phase II study [abstract]. Proc ASCO 2000, 19:492a.
-
(2000)
Proc ASCO
, vol.19
, pp. 492a
-
-
Panza, N.1
Frasci, G.2
Comella, P.3
-
44
-
-
0033044111
-
Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer
-
This phase III study demonstrated that topotecan is at least as effective as CAV the treatment of patients with recurrent SCLC, and results improved control of several symptoms
-
von Pawel J, Schiller JH, Shepherd FA, et al.: Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer. J Clin Oncol 1999, 17:658–667. This phase III study demonstrated that topotecan is at least as effective as CAV in the treatment of patients with recurrent SCLC, and results in improved control of several symptoms.
-
(1999)
J Clin Oncol
, vol.17
, pp. 658-667
-
-
von Pawel, J.1
Schiller, J.H.2
Shepherd, F.A.3
-
45
-
-
0004274677
-
Topotecan (T) vs. observation (OB) following cisplatin (P) plus etoposide (E) in extensive stage small cell lung cancer (ES SCLC) (E7593): a phase III trial of the Eastern Cooperative Oncology Group (ECOG) [abstract]
-
Johnson D, Adak S, Cella D, et al.: Topotecan (T) vs. observation (OB) following cisplatin (P) plus etoposide (E) in extensive stage small cell lung cancer (ES SCLC) (E7593): a phase III trial of the Eastern Cooperative Oncology Group (ECOG) [abstract]. Proc ASCO 2000, 19:482a.
-
(2000)
Proc ASCO
, vol.19
, pp. 482a
-
-
Johnson, D.1
Adak, S.2
Cella, D.3
-
46
-
-
0031811975
-
Dose-finding study of irinotecan and cisplatin plus concurrent radiotherapy for unresectable stage III non-small-cell lung cancer
-
PID: 9683303, COI: 1:CAS:528:DyaK1cXltFWls74%3D
-
Yokoyama A, Kurita Y, Saijo N, et al.: Dose-finding study of irinotecan and cisplatin plus concurrent radiotherapy for unresectable stage III non-small-cell lung cancer. Br J Cancer 1998, 78:257–262. DOI: 10.1038/bjc.1998.474
-
(1998)
Br J Cancer
, vol.78
, pp. 257-262
-
-
Yokoyama, A.1
Kurita, Y.2
Saijo, N.3
-
47
-
-
0003281505
-
Irinotecan (CPT-11) and concurrent radiotherapy in locally advanced non-small cell lung cancer (NSCLC): a phase II study of Japan Clinical Oncology Group (JCOG9504) [abstract]
-
Saka H, Shimokata K, Yoshida S, et al.: Irinotecan (CPT-11) and concurrent radiotherapy in locally advanced non-small cell lung cancer (NSCLC): a phase II study of Japan Clinical Oncology Group (JCOG9504) [abstract]. Proc ASCO 1997, 16:447a.
-
(1997)
Proc ASCO
, vol.16
, pp. 447a
-
-
Saka, H.1
Shimokata, K.2
Yoshida, S.3
-
48
-
-
0024803685
-
Antitumor activities of a novel 9-aminoanthracycline (SM-5887) against mouse experimental tumors and human tumor xenografts
-
PID: 2496061, COI: 1:CAS:528:DyaL1MXhs1Glur8%3D
-
Morisada S, Yanagi Y, Noguchi T, et al.: Antitumor activities of a novel 9-aminoanthracycline (SM-5887) against mouse experimental tumors and human tumor xenografts. Jpn J Cancer Res 1989, 80:69–76.
-
(1989)
Jpn J Cancer Res
, vol.80
, pp. 69-76
-
-
Morisada, S.1
Yanagi, Y.2
Noguchi, T.3
-
49
-
-
0024383338
-
In vitro evaluation of the new anticancer agents KT6149, MX-2, SM5887, menogaril, and liblomycin using cisplatin- or adriamycin-resistant human cancer cell lines
-
PID: 2472873, COI: 1:CAS:528:DyaL1MXlt1Kmtrc%3D
-
Ohe Y, Nakagawa K, Fujiwara Y, et al.: In vitro evaluation of the new anticancer agents KT6149, MX-2, SM5887, menogaril, and liblomycin using cisplatin- or adriamycin-resistant human cancer cell lines. Cancer Res 1989, 49:4098–4102.
-
(1989)
Cancer Res
, vol.49
, pp. 4098-4102
-
-
Ohe, Y.1
Nakagawa, K.2
Fujiwara, Y.3
-
50
-
-
0001118602
-
Phase II study of amrubicin (SM-5887), a 9-amino-anthracycline, in previously untreated patients with extensive stage small-cell lung cancer (ES-SCLC): a West Japan Lung Cancer Group trial [abstract]
-
Yana T, Negoro S, Takada Y, et al.: Phase II study of amrubicin (SM-5887), a 9-amino-anthracycline, in previously untreated patients with extensive stage small-cell lung cancer (ES-SCLC): a West Japan Lung Cancer Group trial [abstract]. Proc ASCO 1998, 17:450a.
-
(1998)
Proc ASCO
, vol.17
, pp. 450a
-
-
Yana, T.1
Negoro, S.2
Takada, Y.3
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