Clinical features of dilated cardiomyopathy in Great Danes and results of a pedigree analysis: 17 cases (1990-2000)

Journal of the American Veterinary Medical Association

Volumn 218, Issue 5, 2001, Pages 729-732

  Meurs, Kathryn M ^a   Miller, Matthew W ^b   Wright, Nicola A ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; CANIS FAMILIARIS;

ANIMAL; ANIMAL DISEASE; ARTICLE; CASE REPORT; CONGESTIVE CARDIOMYOPATHY; DOG; DOG DISEASE; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; GENETICS; MALE; PEDIGREE; RETROSPECTIVE STUDY;

ANIMALS; CARDIOMYOPATHY, DILATED; DOG DISEASES; DOGS; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; MALE; PEDIGREE; RETROSPECTIVE STUDIES;

EID: 0035290721     PISSN: 00031488     EISSN: None     Source Type: Journal    
DOI: 10.2460/javma.2001.218.729     Document Type: Article

References (27)

1. Kasper EK, Agema WRP, Hutchins GM, et al. The causes of dilated cardiomyopathy: a clinicopathologic review of 673 consecutive patients. J Am Coll Cardiol 1994;23:586-590.
2. Sisson D, O'Grady MR, Calvert CA. Myocardial diseases in the dog. In: Fox PR, Sisson D, Moise NS. eds. Textbook of canine and feline cardiology. 2nd ed. Philadelphia: WB Saunders Co, 1999; 581-619.
3. Gooding JP, Robinson WF, Mews GC. Echocardiographic characterization of dilatation cardiomyopathy in the English Cocker Spaniel. Am J Vet Res 1986;47:1978-1983.
4. Kittleson MD, Keene BW, Pion PD. Results of the multicenter spaniel trial (MUST): taurine and carnitine-responsive dilated cardiomyopathy in American Cocker Spaniels with decreased plasma taurine concentration. J Vet Intern Med 1997;11:204-211.
5. Freeman LM, Michel KE, Brown DJ, et al. Idiopathic dilated cardiomyopathy in Dalmatians: nine cases (1990-1995). J Am Vet Med Assoc 1996;209:1592-1596.
6. Harpster N. Boxer cardiomyopathy. A review of the long-term benefits of antiarrhythmic therapy. Vet Clin North Am Small Anim Pract 1991;21:989-1004.
7. Calvert CA, Chapman WL Jr, Toal RL. Congestive cardiomyopathy in Doberman Pinscher dogs. J Am Vet Med Assoc 1982; 181:598-602.
8. Hill BL. Canine idiopathic congestive cardiomyopathy. Compend Contin Educ Pract Vet 1981;6:615-622.
9. Dambach DM, Lannon A, Sleeper MM, et al. Familial dilated cardiomyopathy of young Portuguese Water Dogs. J Vet Intern Med 1999;13:65-71.
10. Tidholm A, Jonsson L. Dilated cardiomyopathy in the Newfoundland: a study of 37 cases (1983-1994). J Am Anim Hosp Assoc 1996;32:465-470.
11. Monnet E, Orton EC, Salman M, et al. Idiopathic dilated cardiomyopathy in dogs: survival and prognostic indicators. J Vet Intern Med 1995;9:12-17.
12. Kittleson MD, Eyster GE, Knowlen GG, et al. Myocardial function in small dogs with chronic mitral regurgitation and severe congestive heart failure. J Am Vet Med Assoc 1984;184:455-459.
13. Bonagura JD, O'Grady MR, Herring DS. Echocardiography. Principles of interpretation. Vet Clin North Am Small Anim Pract 1985;15:1177-1194.
14. Morrison SA, Moise NS, Scarlett J, et al. Effect of breed and body weight on echocardiographic values in four breeds of dogs of differing somatotype. J Vet Intern Med 1992;6:220-224.
15. Ortiz-Lopez R, Schultz KR, Towbin J. Genetic aspects of dilated cardiomyopathy. Progress Ped Cardiol 1996;2:71-82.
16. Hammer TA, Venta PJ, Eyster GE The genetic basis of dilated cardiomyopathy in Doberman Pinschers. Anim Genet 1996;27:101-119.
17. Meurs KM, Spier AW, Miller MW, et al. Familial ventricular arrhythmias in Boxers. J Vet Intern Med 1999;13:437-439.
18. Mestroni L, Rocco C, Gregori D, et al. Familial dilated cardiomyopathy: evidence for genetic and phenotypic heterogeneity. J Am Coll Cardiol 1999;34:181-190.
19. Towbin JA. The role of cytoskeletal proteins in cardiomyopathies. Curr Opin Cell Biol 1998;10:131-139.
20. Towbin JA, Hejtmancik F, Brink P, et al. X-linked dilated cardiomyopathy. Molecular genetic evidence of linkage to the Duchenne muscular dystrophy (dystrophin) gene at the Xp21 locus. Circulation 1993;87:1854-1865.
21. Ortiz-Lopez R, Li H, Su J, et al. Evidence for a dystrophin missense mutation as a cause of X-linked dilated cardiomyopathy. Circulation 1997;95:2434-2440.
22. Li D, Tapscoft T, Gonzalez O, et al. Desmin mutation responsible for idiopathic dilated cardiomyopathy. Circulation 1999;100:461-464.
23. Olson TM, Michels VV, Thibodeau SN, et al. Actin mutations in dilated cardiomyopathy, a heritable form of heart failure. Science 1998;280:750-752.
24. Brodsky GL, Muntoni F, Miocic S, et al. Lamin A/C gene mutation associated with dilated cardiomyopathy with variable skeletal muscle involvement. Circulation 2000;101:473-476.
25. Vollmar AC. Use of echocardiography in the diagnosis of dilated cardiomyopathy in Irish Wolfhounds. J Am Anim Hosp Assoc 1999;35:279-283.
26. Grunig E, Tasman JA, Kucherer H, et al. Frequency and phenotypes of familial dilated cardiomyopathy. J Am Coll Cardiol 1998;31:186-194.
27. Wynne J, Braunwald E. The cardiomyopathies and myocarditis. In: Braunwald E, ed. Heart disease. 5th ed. Philadelphia: WB Saunders Co, 1997;1407-1463.