The response of human dendritic cells to recombinant adenovirus, recombinant Mycobacterium bovis Bacillus Calmette Guerin and biolistic methods of antigen delivery: Different induction of contact-dependant and soluble signals

Immunology Letters

Volumn 76, Issue 2, 2001, Pages 79-88

  Smith, Steven G ^a   Patel, Poulam M ^a   Selby, Peter J ^a   Jackson, Andrew M ^a  

^a ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Adenovirus; BCG; Dendritic cell

Indexed keywords

B7 ANTIGEN; BCG VACCINE; CD1 ANTIGEN; CD14 ANTIGEN; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; GLYCOPROTEIN P 15095; GREEN FLUORESCENT PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; RECOMBINANT VACCINE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BIOLISTIC TRANSFORMATION; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; GENE EXPRESSION; GENE GUN; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; IMMUNE RESPONSE; MAJOR HISTOCOMPATIBILITY COMPLEX; MYCOBACTERIUM BOVIS; PHENOTYPE; PRIORITY JOURNAL; REPORTER GENE; T LYMPHOCYTE ACTIVATION; VIRUS RECOMBINANT;

ADENOVIRUSES, HUMAN; ANTIGEN PRESENTATION; CELL DIVISION; CELL LINE; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; LUMINESCENT PROTEINS; MONOCYTES; MYCOBACTERIUM BOVIS; PHENOTYPE; RECOMBINATION, GENETIC; SOLUBILITY; TRANSFECTION;

EID: 0035280848     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2478(00)00324-2     Document Type: Article

References (37)

1. Dendritic cells and the control of immunity
2. T-cell priming by type-1 and type-2 polarized dendritic cells: The concept of a third signal
3. Dendritic cell vaccines for cancer immunotherapy
4. Generation of mature dendritic cells from human blood. An improved method with special regard to clinical application
5. 280-288), induce pairs of T-cell cultures with similar phenotype and lytic activity
6. Autologous human dendriphages pulsed with synthetic or natural tumor peptides elicit tumor-specific CTLs in vitro
7. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells
8. Human tumor antigens recognized by T lymphocytes
9. Report of immune monitoring of prostate cancer patients undergoing T-cell therapy using dendritic cells pulsed with HLA-A2-specific peptides from prostate-specific membrane antigen (PSMA)
10. Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma
11. Dendritic cells retrovirally transduced with a model antigen gene are therapeutically effective against established pulmonary metastases
12. Dendritic cells genetically modified with an adenovirus vector encoding the cDNA for a model antigen induce protective and therapeutic antitumor immunity
13. Generation of melanoma-specific cytotoxic T lymphocytes by dendritic cells transduced with a MART-1 adenovirus
14. Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro: Enhancement by cotransfection of genes encoding the Th1- biasing cytokines IL-12 and IFN-alpha
15. DNA-based immunization by in vivo transfection of dendritic cells
16. DNA vaccination: Transfection and activation of dendritic cells as key events for immunity
17. Predominant role for directly transfected dendritic cells in antigen presentation to CD8+ T cells after gene gun immunization
18. Enrichment of an antigen-specific T cell response by retrovirally transduced human dendritic cells
19. BCG immunotherapy of bladder cancer: 20 years on
20. Activation of human dendritic cells following infection with Mycobacterium tuberculosis
21. Bacillus Calmette-Guerin mycobacteria stimulate human blood dendritic cells
22. Activation of human dendritic cells by bacillus Calmette-Guerin
23. Protection against aerosol Mycobacterium tuberculosis infection using Mycobacterium bovis Bacillus Calmette Guerin-infected dendritic cells
24. Enhanced antigen-presenting activity and tumour necrosis factor-alpha- independent activation of dendritic cells following treatment with Mycobacterium bovis bacillus Calmette-Guerin
25. High efficiency adenovirus-mediated gene transfer to human dendritic cells
26. Adenoviruses activate human dendritic cells without polarization toward a T-helper type 1-inducing subset
27. Recombinant adenovirus is an efficient and non-perturbing genetic vector for human dendritic cells
28. Quantitative analysis of the immunopotency of genetically transfected dendritic cells
29. A simplified system for generating recombinant adenovirus
30. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumour necrosis factor alpha
31. Vaccinia virus inhibits the maturation of human dendritic cells: A novel mechanism of immune evasion
32. Immune response induced by BCG recombinant for human papillomavirus L1 and E7 proteins
33. Delivery of DNA vaccines by attenuated intracellular bacteria
34. Cytolytic T-cell responses to human dendritic cells and macrophages infected with Mycobacterium bovis BCG and recombinant BCG secreting lysteriolysin
35. Recombinant Mycobacterium bovis BCG secreting functional IL-2 enhances gamma interferon production by splenocytes
36. Natural adjuvants: Endogenous activators of dendritic cells
37. Kinetics of dendritic cell activation: Impact on priming of Th1, Th2 and nonpolarised T cells