SCOPUS 정보 검색 플랫폼

Farmaco

Volumn 56, Issue 1-2, 2001, Pages 45-50

Lipoprotein-associated PLA2 inhibition - A novel, non-lipid lowering strategy for atherosclerosis therapy

(6) Leach, Colin A a Hickey, Deirdre M B a Ife, Robert J a Macphee, Colin H a Smith, Stephen A a Tew, David G a

a GLAXOSMITHKLINE (United Kingdom)

Author keywords

Atherosclerosis therapy; Enzyme inhibitors; Lp PLA2; Phospholipase A2

Indexed keywords

AZETIDINONE DERIVATIVE; LOW DENSITY LIPOPROTEIN; PHOSPHOLIPASE A2; PYRIMIDINONE DERIVATIVE; SB 222657; SB 244323; UNCLASSIFIED DRUG; ENZYME INHIBITOR; LIPOPROTEIN ASSOCIATED PHOSPHOLIPASE A(2); LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A(2); PHOSPHOLIPASE A;

ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CHRONIC INFLAMMATION; CONFERENCE PAPER; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; FOAM CELL; HYPERCHOLESTEROLEMIA; LIPID OXIDATION; NONHUMAN; STRUCTURE ACTIVITY RELATION; ARTERIOSCLEROSIS; ARTICLE; DRUG ANTAGONISM; HUMAN;

ARTERIOSCLEROSIS; ENZYME INHIBITORS; HUMANS; PHOSPHOLIPASES A; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035273244 PISSN: 0014827X EISSN: None Source Type: Journal
DOI: 10.1016/S0014-827X(01)01011-4 Document Type: Conference Paper

Times cited : (46)

References (13)

1
- 0032850280
- Preventive cardiology
- (1999) Curr. Opin. Cardiol. , vol.14 , pp. 382-391
- Foody, J.M.¹

2
- 0033552883
- Atherosclerosis - an inflammatory disease
- (1999) N. Engl. J. Med. , vol.340 , pp. 115-126
- Ross, R.¹

3
- 0027470908
- Atherosclerosis: what is it and why does it occur?
- (1993) Br. Heart J. , vol.69
- Davies, M.J.¹ Woolf, N.²

4
- 0030446822
- 2 in atherogenesis
- (1996) Pharmacol. Rev. Commun. , vol.8 , pp. 309-315
- Macphee, C.H.¹ Milliner, K.² Moores, K.³ Tew, D.G.⁴

5
- 0029986601
- Purification, properties, sequencing and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins
- (1996) Atheroscler. Thromb. Vasc. Biol. , vol.16 , pp. 591-599
- Tew, D.G.¹ Southan, C.² Rice, S.Q.J.³ Lawrence, M.P.⁴ Haodong, L.⁵ Boyd, H.F.⁶ Moores, K.⁷ Gloger, I.S.⁸ Macphee, C.H.⁹

6
- 0027507082
- Role of oxidised low density lipoprotein in atherogenesis
- (1993) Br. Heart J. , vol.69
- Witztum, J.L.¹

7
- 0030877832
- Oxidized lipids in atherogenesis: formation, destruction and action
- (1997) Thromb. Haemostasis , vol.78 , pp. 195-199
- Berliner, J.¹ Leitinger, N.² Watson, A.³ Huber, J.⁴ Fogelman, A.⁵ Navab, M.⁶

8
- 0004993133
- Lipoprotein-associated phospholipase A2, an inflammatory marker and novel independent risk factor in the West of Scotland Coronary Prevention Study
- (2000) Atherosclerosis , vol.151 , pp. 89
- Packard, C.J.¹ O'Reilly, D.² Caslake, M.J.³ McIntosh, G.⁴ Macphee, C.H.⁵ Suckling, K.E.⁶ Krishna, M.⁷ Rumley, A.⁸ Lowe, G.⁹

9
- 0033104911
- Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor
- (1999) Biochem. J. , vol.338 , pp. 479-487
- Macphee, C.H.¹ Moores, K.E.² Boyd, H.F.³ Dhanak, D.⁴ Ife, R.J.⁵ Leach, C.A.⁶ Leake, D.S.⁷ Milliner, K.J.⁸ Patterson, R.A.⁹ Suckling, K.E.¹⁰ Tew, D.G.¹¹ Hickey, D.M.B.¹²

10
- 0001452368
- Anti-atherosclerotic effect of SB-244323, a lipoprotein associated phospholipase A2 inhibitor, in WHHL rabbits
- (2000) Atherosclerosis , vol.151 , pp. 166
- Benson, G.M.¹ Grimsditch, D.² Milliner, K.³ Moores, K.⁴ Boyd, H.⁵ Tew, D.⁶ Hickey, D.⁷ Ife, R.⁸ Suckling, K.⁹ Macphee, C.¹⁰

11
- 18144439390
- 2
- (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 395-398
- Boyd, H.F.¹ Flynn, S.T.² Hickey, D.M.B.³ Ife, R.J.⁴ Jones, M.⁵ Leach, C.A.⁶ Macphee, C.H.⁷ Milliner, K.J.⁸ Rawlings, D.A.⁹ Slingsby, B.P.¹⁰ Smith, S.A.¹¹ Stansfield, I.G.¹² Tew, D.G.¹³ Theobald, C.J.¹⁴

12
- 0034694360
- 2
- (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 2557-2562
- Boyd, H.F.¹ Fell, S.C.M.² Flynn, S.T.³ Hickey, D.M.B.⁴ Ife, R.J.⁵ Leach, C.A.⁶ Macphee, C.H.⁷ Milliner, K.J.⁸ Moores, K.E.⁹ Pinto, I.L.¹⁰ Porter, R.A.¹¹ Rawlings, D.A.¹² Smith, S.A.¹³ Stansfield, I.G.¹⁴ Tew, D.G.¹⁵ Theobald, C.J.¹⁶ Whittaker, C.M.¹⁷

13
- 0004997297
- CLOGP Version 4.62, Daylight Chemical Information Systems, Mission Viejo, CA, USA.

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.