Restriction of mesendoderm to a single blastomere by the combined action of SKN-1 and a GSK-3β homolog is mediated by MED-1 and -2 in C. elegans

Molecular Cell

Volumn 7, Issue 3, 2001, Pages 475-485

  Maduro, Morris F ^a   Meneghini, Marc D ^b   Bowerman, Bruce ^b   Broitman Maduro, Gina ^a   Rothman, Joel H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF OREGON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN; PROTEIN GSK 3BETA; PROTEIN SGG 1; TRANSCRIPTION FACTOR SKN 1; UNCLASSIFIED DRUG; WNT PROTEIN;

ARTICLE; BLASTOMERE; CAENORHABDITIS ELEGANS; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; EMBRYO; EMBRYO DEVELOPMENT; ENDODERM; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENOTYPE; GERM LAYER; MALE; NONHUMAN; STEM CELL;

CAENORHABDITIS ELEGANS; NEMATODA; VERTEBRATA;

EID: 0035265680     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00195-2     Document Type: Article

References (56)

1. Animal-vegetal axis patterning mechanisms in the early sea urchin embryo
2. A fork head/HNF-3 homolog expressed in the pharynx and intestine of the Caenorhabditis elegans embryo
3. Transcriptional repression by the Caenorhabditis elegans germ-line protein PIE-1
4. Formation of a monomeric DNA binding domain by Skn-1 bZIP and homeodomain elements
5. skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. elegans embryo
6. The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos
7. The maternal par genes and the segregation of cell fate specification activities in early Caenorhabditis elegans embryos
8. Wnt signaling: A common theme in animal development
9. Dorsal downregulation of GSK3beta by a non-Wnt-like mechanism is an early molecular consequence of cortical rotation in early Xenopus embryos
10. Expression of transcription factor HNF-4 in extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst
11. Vertebrate tinman homologues and cardiac differentiation
12. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
13. The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine
14. Induction of gut in Caenorhabditis elegans embryos
15. Establishment of gut fate in the E lineage of C. elegans: The roles of lineage-dependent mechanisms and cell interactions
16. An analysis of the response to gut induction in the C. elegans embryo
17. Rescue of Caenorhabditis elegans pharyngeal development by a vertebrate heart specification gene
18. lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans
19. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
20. Spatial and temporal control target pal-1 blastomere-specification activity to a single blastomere lineage in C. elegans embryos
21. Binary specification of the embryonic lineage in Caenorhabditis elegans
22. Distinct requirements for somatic and germline expression of a generally expressed Caenorhabditis elegans gene
23. Vertebrate mesendoderm induction and patterning
24. CeMyoD accumulation defines the body wall muscle cell fate during C. elegans embryogenesis
25. The Caenorhabditis elegans LIN-26 protein is required to specify and/or maintain all non-neuronal ectodermal cell fates
26. pop-1 encodes an HMG box protein required for the specification of a mesoderm precursor in early C. elegans embryos
27. POP-1 and anterior-posterior fate decisions in C. elegans embryos
28. Identification and cloning of unc-119, a gene expressed in the Caenorhabditis elegans nervous system
29. Efficient gene transfer in C. elegans: Extrachromosomal maintenance and integration of transforming sequences
30. The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos
31. The PIE-1 protein and germline specification in C. elegans embryos
32. MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans
33. lin-12 and glp-1 are required zygotically for early embryonic cellular interactions and are regulated by maternal GLP-1 signaling in Caenorhabditis elegans
34. Fork head domain genes in zebrafish
35. The Caenorhabditis elegans NK-2 class homeoprotein CEH-22 is involved in combinatorial activation of gene expression in pharyngeal muscle
36. Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis
37. Cellular interactions in early C. elegans embryos
38. The glp-1 locus and cellular interactions in the early C. elegans embryo
39. Gata5 is required for the development of the heart and endoderm in zebrafish
40. Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos
41. WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans
42. A new DNA-binding motif in the Skn-1 binding domain-DNA complex
43. Reversal of cellular polarity and early cell-cell interaction in the embryos of Caenorhabditis elegans
44. Wnt pathway components orient a mitotic spindle in the early Caenorhabditis elegans embryo without requiring gene transcription in the responding cell
45. Specification of cell fates in the early embryo
46. Soma-germline asymmetry in the distributions of embryonic RNAs in Caenorhabditis elegans
47. Repression of gene expression in the embryonic germ lineage of C. elegans
48. elt-1, an embryonically expressed Caenorhabditis elegans gene homologous to the GATA transcription factor family
49. Temporal and spatial expression patterns of the small heat shock (hsp-16) genes in transgenic Caenorhabditis elegans
50. The embryonic cell lineage of the nematode Caenorhabditis elegans
51. pos-1 encodes a cytoplasmic zinc-finger protein essential for germline specification in C. elegans
52. Heritable and inducible genetic interference by double-stranded DNA encoded by transgenes
53. Genetic requirements for PIE-1 localization and inhibition of gene expression in the embryonic germ lineage of Caenorhabditis elegans
54. Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm
55. Origin and development of the zebrafish endoderm
56. end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos