An IgM anti-MBP Ab in a case of Waldenstrom's macroglobulinemia with polyneuropathy expressing an idiotype reactive with an MBP epitope immunodominant in MS and EAE

Journal of Neuroimmunology

Volumn 113, Issue 1, 2001, Pages 163-169

  Noerager, Brett D ^a   Inuzuka, Takashi ^b   Kira, Jun ichi ^c   Blalock, J Edwin ^a,d   Whitaker, John N ^d,e   Galin, F Shawn ^a,f  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b NIIGATA UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e University of Alabama at Birmingham   (United States)

^f BIRMINGHAM VA MEDICAL CENTER   (United States)

Author keywords

Idiotypic; MBP; MS; Waldenstrom's macroglobulinemia

Indexed keywords

ACTIN; AUTOANTIGEN; CITRULLINE; DNA; EPITOPE; GENE PRODUCT; IMMUNOGLOBULIN IDIOTYPE; IMMUNOGLOBULIN M ANTIBODY; ISOPROTEIN; MACROGLOBULIN; MYELIN BASIC PROTEIN; PEPTIDE FRAGMENT; THYROGLOBULIN;

ALLERGIC ENCEPHALOMYELITIS; ANTIGEN BINDING; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNITY; CASE REPORT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; MOUSE; MULTIPLE SCLEROSIS; NERVE CELL LESION; NONHUMAN; PATHOGENESIS; PLASMA CELL DYSCRASIA; POLYNEUROPATHY; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; WALDENSTROEM MACROGLOBULINEMIA;

ANIMALS; AUTOANTIBODIES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNODOMINANT EPITOPES; IMMUNOGLOBULIN M; MACROGLOBULINS; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; PEPTIDE FRAGMENTS; POLYNEUROPATHIES; RABBITS; WALDENSTROM MACROGLOBULINEMIA;

EID: 0035255042     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(00)00425-2     Document Type: Article

References (22)

1. Neurologic manifestations of macroglobulinemia
2. Deletion and editing of B cells that express antibodies to DNA
3. Polyneuropathy with monoclonal gammopathy
4. Waldenstrom's macroglobulinemia and peripheral neuropathy: A clinical and immunologic study of 25 patients
5. A new V gene expressed in lambda-2 light chains of the mouse
6. Waldenstrom's Macroglobulinemia
7. Murine Vλx and Vλx-containing antibodies bind human myelin basic protein
8. A novel monoclonal antibody which reacts with a high molecular weight neuronal cytoplasmic protein and myelin basic protein (MBP) in a patient with macroglobulinemia
9. Plasma cell dyscrasia and peripheral neuropathy: Identification of the myelin antigens that react with human paraproteins
10. Monoclonal IgM with unique specificity to gangliosides GM1 and GD1b and to lacto-N-tetraose associated with human motor neuron disease
11. A Vλx-bearing monoclonal antibody with similar specificity and sequence to encephalitogenic T cells
12. Peripheral neuropathy in macroglobulinemia: Incidence and antigen-specificity of M proteins
13. Structure of a third murine immunoglobulin λ light chain variable region that is in laboratory mice
14. Mouse Vλx gene sequence generates no junctional diversity and is conserved in mammalian species
15. Motor neuron disease and plasma cell dyscrasia
16. Incipient myelomatosis or 'essential' hyperglobulinemia with fibrinogenopenia - A new syndrome?
17. The sequential limited degradation of bovine myelin basic protein by bovine brain cathepsin D
18. An immunological comparison of human myelin basic protein and its modified citrullinated isoform, C8
19. The isolation, characterization, and lipid-aggregating properties of a citrulline containing myelin basic protein
20. Recognition of the immunodominant myelin basic protein by autoantibodies and HLA-DR2-restricted T cell clones from multiple sclerosis patients
21. Interstrain cross-reactive idiotypes on monoclonal antibodies to an encephalitogenic myelin basic protein peptide
22. Specific modulation of T cells and murine experimental allergic encephalomyelitits by monoclonal antiidiotypic antibodies