Human ovarian surface epithelial (OSE) cells express LH/HCG receptors, and HCG inhibits apoptosis of ose cells via up-regulation of insulin-like growth factor-1

International Journal of Cancer

Volumn 91, Issue 3, 2001, Pages 309-315

  Kuroda, Hideki ^a   Mandai, Masaki ^a,b   Konishi, Ikuo ^a   Tsuruta, Yuko ^b   Kusakari, Takashi ^a   Kariya, Masatoshi ^b   Fujii, Shingo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Hcg; Igf 1; LH hCG receptor; Ovarian surface epithelium (OSE); Proliferation

Indexed keywords

CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN RECEPTOR; LUTEINIZING HORMONE; LUTEINIZING HORMONE RECEPTOR; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

ADULT; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL LINE; CHORIONIC GONADOTROPIN; DNA FRAGMENTATION; EPITHELIAL CELLS; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; IODINE RADIOISOTOPES; OVARY; RECEPTORS, LH;

EID: 0035254982     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0215(200002)9999:9999<::AID-IJC1060>3.0.CO;2-0     Document Type: Article

References (35)

1. Steroid receptors and Ki-67 activity in ovarian cancer and in normal ovary
2. Epidermal growth factor expression in normal ovarian epithelium and ovarian cancer
3. Immunohistochemical localization of c-erbB-2 protein and epidermal growth factor receptor in normal surface epithelium, surface inclusion cysts, and common epithelial tumours of the ovary
4. Transforming growth factor-alpha localization and role in surface epithelium of normal human ovaries and in ovarian carcinoma lines
5. A simplified method to culture human ovarian surface epithelium
6. Isolation, growth and characteristics of human ovarian surface epithelium
7. Characterization of cultured human ovarian surface epithelial cells: Phenotypic plasticity and premalignant changes
8. Fas antigen-mediated apoptosis of ovarian surface epithelial cells
9. The effects of platelet-derived growth factor and receptor on normal and neoplastic human ovarian surface epithelium
10. Regulation of proliferation and apoptosis by epidermal growth factor and protein kinase C in human ovarian surface epithelial cells
11. Expression profile of senescence-associated beta-galactosidase and activation of telomerase in human ovarian surface epithelial cells undergoing immortalization
12. The natural history and treatment of ovarian cancer
13. Incessant ovulation - A factor in ovarian neoplasia?
14. Ovarian cancer in infertile women during or after ovulation-induction therapy: Expression of LH/hCG receptors and sex steroid receptors
15. Messenger ribonucleic acid expression of LH/ hCG receptor gene in human ovarian carcinomas
16. Human chorionic gonadotropin (hCG) inhibits cisplatin-induced apoptosis in ovarian cancer cells: Possible role of up-regulation of insulin-like growth factor-1 by hCG
17. Cloning and sequencing of human LH/hCG receptor cDNA
18. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
19. Follicle-stimulating hormone receptor is expressed in human ovarian surface epithelium and fallopian tube
20. Binding sites for gonadotropins in human postmenopausal ovaries
21. The luteotropin/choriogonadotropin receptor-4 years later
22. Cell lines derived from human ovarian carcinomas: Growth stimulation by gonadotropic and steroid hormones
23. Gonadotropins, estradiol, and growth factors regulate epithelial ovarian cancer cell growth
24. Gonadotropin suppression of apoptosis in cultured preovulatory follicles: Mediatory role of endogenous insulin-like growth factor I
25. Gonadotropins induce accumulation of insulin-like growth factor I mRNA in pig granulosa cells in vitro
26. Suppression of interleukin-1 beta-converting enzyme-mediated cell death by insulin-like growth factor
27. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
28. Molecular regulation of apoptosis: Genetic controls on cell death
29. Epidemiology, etiology, and fertility drugs in ovarian epithelial carcinoma: Where are we today?
30. Inhibition of apoptosis during development of colorectal cancer
31. Bax suppresses tumorigenesis and stimulates apoptosis in vivo
32. Disruption of the pRb/E2F pathway and inhibition of apoptosis are major oncogenic events in liver constitutively expressing c-myc and transforming growth factor alpha
33. Characteristics relating to ovarian cancer risk: Collaborative analysis of 12 US case-control studies. IV. The pathogenesis of epithelial ovarian cancer
34. IFFS expert group report on the Whittemore study related to the risk of ovarian cancer associated with the use of infertility agents