6-Formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation

Free Radical Biology and Medicine

Volumn 30, Issue 3, 2001, Pages 248-259

  Arai, Toshiyuki ^a   Endo, Nobuyuki ^b   Yamashita, Kouhei ^a   Sasada, Masataka ^a,b   Mori, Hiroko ^a   Ishii, Hisanari ^a   Hirota, Kiichi ^a   Makino, Keisuke ^b   Fukuda, Kazuhiko ^a  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

6 formylpterin; Apoptosis; Cell proliferation; Conjugated pterin; Fas; NADH; Reactive oxygen species

Indexed keywords

BIOPTERIN; FAS ANTIBODY; HYDROGEN PEROXIDE; NEOPTERIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; PTERIN 6 ALDEHYDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE; UNCLASSIFIED DRUG; XANTHINE OXIDASE INHIBITOR;

APOPTOSIS; ARTICLE; CATALYSIS; CELL LINE; CELL PROLIFERATION; CHEMICAL REACTION; CONTROLLED STUDY; ELECTRON TRANSPORT; HUMAN; HUMAN CELL; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

ANTIGENS, CD95; APOPTOSIS; CATALASE; CELL DIVISION; CHELATING AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEFEROXAMINE; ELECTROCHEMISTRY; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYME INHIBITORS; HL-60 CELLS; HUMANS; HYDROGEN PEROXIDE; JURKAT CELLS; NAD; NUCLEOTIDES; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; PTERIDINES; PTERINS; REACTIVE OXYGEN SPECIES; SUPEROXIDES; XANTHINE OXIDASE;

EID: 0035253850     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(00)00465-2     Document Type: Article

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