Phosphatidylserine exposure and phagocytosis of apoptotic cells

Methods in Cell Biology

Volumn , Issue 66, 2001, Pages 339-364

  Williamson, Patrick ^a   Van Den Eijnde, Stefan ^b   Schlegel, Robert A ^c  

^a AMHERST COLLEGE   (United States)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035237362     PISSN: 0091679X     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (28)

1. Blankenberg, F. G., Katsikis, P. D., Tait, J. F., Davis, R. E., Naumovski, L., Ohtsuki, K., Kopiwoda, S., Abrams, M. J., Darkes, M., Robbins, R. C., Maecker, H. T., and Strauss, H. W. (1998). In vivo detection and imaging of phosphatidylserine expression during programmed cell death. Proc. Natl. Acad. Sci. USA 95, 6349-6354.
2. Burger, A., Berendes, R., Voges, D., Huber, R., and Demange, P. (1993). A rapid and efficient purification method for recombinant Annexin V for biophysical studies. FEBS. Lett. 329, 25-28.
3. Callahan, M. K., Williamson, P., and Schlegel, R. A. (2000). Surface expression of phosphatidylserine on macrophages is required for phagocytosis of apoptotic thymocytes. Cell Death. Differ. 7, 645-653.
4. Choe, H. R., Schlegel, R. A., Rubin, E., Williamson, P., and Westerman, M. P. (1986). Alteration of red cell membrane organization in sickle cell anaemia. Br. J. Haematol 63, 761-773.
5. Choe, H. R., Williamson, P., Rubin, E., and Schlegel, R. A. (1985). Disruption of phospholipid asymmetry in erythrocyte vesicles deficient in spectrin. Cell. Biol. Int. Rep. 9, 597-606.
6. Devaux, P. F. (1991). Static and dynamic lipid asymmetry in cell membranes. Biochemistry 30, 1163-1173.
7. Diaz, C., Lee, A. T., McConkey, D. J., and Schroit, A. J. (1999). Phosphatidylserine externalization during differentiation-triggered apoptosis of erythroleukemic cells. Cell Death Differ. 6, 218-226.
8. Fadeel, B., Gleiss, B., Hogstrand, K., Chandra, J., Wiedmer, T., Sims, P. J., Henter, J. I., Orrenius, S., and Samali, A. (1999). Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression. Biochem. Biophys. Res. Commun. 266, 504-511.
9. Fadok, V. A., Voelker, D. R., Campbell, P. A., Cohen, J. J., Bratton, D. L., and Henson, P. M. (1992). Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immun. 148, 2207-2216.
10. Glucksmann, A. (1951). Cell deaths in normal vertebrate ontogeny. Biol. Rev. Cam. Philos. Soc. 26, 59-86.
11. Krahling, S., Callahan, M. K., Williamson, P., and Schlegel, R. A. (1999). Exposure of phosphatidylserine is a general feature in the phagocytosis of apoptotic lymphocytes by macrophages. Cell. Death. Differ 6, 183-189.
12. Kroemer, G., Dallaporta, B., and RescheRigon, M. (1998). The mitochondrial death/life regulator in apoptosis and necrosis. Annu. Rev. Physiol. 60, 619-642.
13. Martin, S. J., Reutelingsperger, C. P. M., Mcgahon, A. J., Rader, J. A., Vanschie, R. C. A. A., Laface, D. M., and Green, D. R. (1995). Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med. 182, 1545-1556.
14. McEvoy, L., Schlegel, R. A., Williamson, P., and Del Buono, B. J. (1988). Mercoyanine 540 as a flow cytometric probe of membrane lipid organization in leukocytes. J. Leukocute Biol. 44, 337-344.
15. Mower, D. A., Peckham, D. W., Illera, V. A., Fishbaugh, J. K., Stunz, L. L., and Ashman, R. F. (1994). Decreased membrane phospholipid packing and decreased cell size precede DNA cleavage in mature mouse B cell apoptosis. J. Immun. 152, 4832-4842.
16. Pradhan, D., Krahling, S., Williamson, P., and Schlegel, R. A. (1997). Multiple systems for recognition of apoptotic lymphocytes by macrophages. Mol. Biol. Cell. 8, 767-778.
17. Reutelingsperger, C. P., Hornstra, G., and Hemker, H. C. (1985). Isolation and partial purification of a novel anticoagulant from arteries of human umbilical cord. Eur. J. Bichem. 151, 625-629.
18. Schlegel, R. A., Reed, J. A., McEvoy, L., Algarin, L., and Williamson, P. (1987). Phospholipid asymmetry of loaded red cells. Methods. Enzymol. 149, 281-293.
19. Schlegel, R. A., Stevens, M., Lumley-Sapanski, K., and Williamson, P. (1993). Altered lipid packing identifies apoptotic thymocytes. Immunol. Lett. 36, 283-288.
20. van den Eijnde, S. M., Boshart, L., Baehrecke, E. H., DeZeeuw, C. I., Reutelingsperger, C. P. M., and VermeijKeers, C. (1998). Cell surface exposure of phosphatidylserine during apoptosis is phylogenetically conserved. Apoptosis 3, 9-16.
21. van den Eijnde, S. M., Boshart, L., Reutelingsperger, C. P. M., DeZeeuw, C. I., and Vermeij-Keers, C. (1997a). Phosphatidylserine is exposed by apoptotic cells in mouse embryos in vivo. Eur. J. Morphol. 35, 54-55.
22. van den Eijnde, S. M., Boshart, L., Reutelingsperger, C. P. M., de Zeeuw, C. I., and Vermeij-Keers, C. (1997b). Phosphatidylserine plasma membrane asymmetry in vivo: a pancellular phenomenon which alters during apoptosis. Cell Death. Differ. 4, 311-316.
23. van den Eijnde, S. M., Lips, J., Boshart, L., Vermeij-Keers, C., Marani, E., Reutelingsperger, C. P., and De Zeeuw, C. I. (1999). Spatiotemporal distribution of dying neurons during early mouse development. Eur. J. Neurosci. 11, 712-724.
24. van den Eijnde, S. M., Luijsterburg, A. J. M., Boshart, L., DeZeeuw, C. I., vanDierendonck, J. H., Reutelingsperger, C. P. M., and Vermeij-Keers, C. (1997c). In situ detection of apoptosis during embryogenesis with Annexin V: From whole mount to ultrastructure. Cytometry 29, 313-320.
25. Verhoven, B., Schlegel, R. A., and Williamson, P. (1995). Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes. J. Exp. Med. 182, 1597-1601.
26. Watanabe, M., Choudhry, A., Berlan, M., Singal, A., Siwik, E., Mohr, S., and Fisher, S. A. (1998). Developmental remodeling and shortening of the cardiac outflow tract involves myocyte programmed cell death. Development 125, 3809-3820.
27. Williamson, P., and Schlegel, R. A. (1994). Back and forth: The regulation and function of transbilayer phospholipid movement in eukaryotic cells. Mol. Membr. Biol. 11, 199-216.
28. Wu, Y. C., and Horvitz, H. R. (1998). The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters. Cell 93, 951-960.