The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters

Cell

Volumn 93, Issue 6, 1998, Pages 951-960

  Wu, Yi Chun ^a   Horvitz, H Robert ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; CED 7 PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL ADHESION; CHROMOSOME 3; DNA SEQUENCE; EMBRYO DEVELOPMENT; GENE ISOLATION; GENE LOCATION; GENE MAPPING; MOLECULAR CLONING; MOSAICISM; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

CAENORHABDITIS ELEGANS; CESTODA; INVERTEBRATA; MAMMALIA; NEMATODA;

EID: 0032511145     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81201-5     Document Type: Article

References (64)

1. Allikmets, R., Singh, N., Sun, H., Shroyer, N.F., Hutchinson, A., Chidambaram, A., Gerrard, B., Baird, L., Stauffer, D., Peiffer, A., et al. (1997). A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy. Nature Genet. 15, 236-246.
2. Austin, J., and Kimble, J. (1987). glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans. Cell 51, 589-599.
3. Azzaria, M., Schurr, E., and Gros, P. (1989). Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance. Mol. Cell. Biol. 9, 5289-5297.
4. Becq, F., Hamon, Y., Bajetto, A., Gola, M., Verrier, B., and Chimini, G. (1997). ABC1, an ATP binding cassette transporter required for phagocytosis of apoptotic cells, generates a regulated anion flux after expression in Xenopus laevis oocytes. J. Biol. Chem. 272, 2695-2699.
5. Berkower, C., and Michaelis, S. (1991). Mutational analysis of the yeast a-factor transporter STE6, a member of the ATP binding cassette (ABC) protein superfamily. EMBO J. 10, 3777-3785.
6. Bloom, L., and Horvitz, H.R. (1997). The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation. Proc. Natl. Acad. Sci. USA 94, 3414-3419.
7. Brenner, S. (1974). The genetics of Caenorhabditis elegans. Genetics 77, 71-94.
8. Carson, M.R., Travis, S.M., and Welsh, M.J. (1995). The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity. J. Biol. Chem. 270, 1711-1717.
9. Cheng, S.H., Rich, D.P., Marshall, J., Gregory, R.J., Welsh, M.J., and Smith, A.E. (1991). Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel. Cell 66, 1027-1036.
10. Clark, S.G., Chisholm, A.D., and Horvitz, H.R. (1993). Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39. Cell 74, 43-55.
11. Conforti, G., Zanetti, A., Pasquali-Ronchetti, I., Quaglino, D., Jr., Neyroz, P., and Dejana, E. (1990). Modulation of vitronectin receptor binding by membrane lipid composition. J. Biol. Chem. 265, 4011-4019.
12. Connors, T.D., Van Raay, T.J., Petry, L.R., Klinger, K.W., Landes, G.M., and Burn, T.C. (1997). The cloning of a human ABC gene (ABC3) mapping to chromosome 16p13.3. Genomics 39, 231-234.
13. Coulson, A., Sulston, J., Brenner, S., and Karn, J. (1986). Toward a physical map of the genome of the nematode Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 83, 7821-7825.
14. Culotti, J.G., and Russell, R.L. (1978). Osmotic avoidance defective mutants of the nematode Caenorhabditis elegans. Genetics 90, 243-256.
15. Duvall, E., Wyllie, A.H., and Morris, R.G. (1985). Macrophage recognition of cells undergoing programmed cell death (apoptosis). Immunology 56, 351-358.
16. Ellis, R., Jacobson, D.M., and Horvitz, H.R. (1991a). Genes required for the engulfment of cell corpses during programmed cell death in C. elegans. Genetics 129, 79-94.
17. Ellis, R.E., Yuan, J., and Horvitz, H.R. (1991b). Mechanisms and functions of cell death. Annu. Rev. Cell Biol. 7, 663-698.
18. Fadok, V.A., Savill, J.S., Haslett, C., Bratton, D.L., Doherty, D.E., Campbell, P.A., and Henson, P.M. (1992a). Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells. J. Immunol. 149, 4029-4035.
19. Fadok, V.A., Voelker, D.R., Campbell, P.A., Cohen, J.J., Bratton, D.L., and Henson, P.M. (1992b). Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148, 2207-2216.
20. Fath, M.J., and Kolter, R. (1993). ABC transporters: bacterial exporters. Microbiol. Rev. 57, 995-1017.
21. Finney, M., and Ruvkun, G. (1990). The unc-86 gene product couples cell lineage and cell identity in C. elegans. Cell 63, 895-905.
22. Frohman, M.A., Dush, M.K., and Martin, G.R. (1988). Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. Proc. Natl. Acad. Sci. USA 85, 8998-9002.
23. Fry, D.C., Byler, D.M., Susi, H., Brown, E.M., Kuby, S.A., and Mildvan, A.S. (1988). Solution structure of the 45-residue Mg ATP-binding peptide of adenylate kinase as examined by 2-D NMR, FTIR, and CD spectroscopy. Biochemistry 27, 3588-3598.
24. Greenwald, I., Coulson, A., Sulston, J., and Priess, J. (1987). Correlation of the physical and genetic maps in the lin-12 region of C. elegans. Nucl. Acids Res. 15, 2295-2307.
25. Guenther, C., and Garriga, G. (1996). Asymmetric distribution of the C. elegans HAM-1 protein in neuroblasts enables daughter cells to adopt distinct fates. Development 122, 3509-3518.
26. Guo, X.D., Johnson, J.J., and Kramer, J.M. (1991). Embryonic lethality caused by mutations in basement membrane collagen of C. elegans. Nature 349, 707-709.
27. Harlow, E., and Lane, D. (1988). Antibodies: A Laboratory Manual. (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press).
28. Hart, S.P., Haslett, C., and Dransfield, I. (1996). Recognition of apoptotic cells by phagocytes. Experientia 52, 950-956.
29. Hedgecock, E.M., and Herman, R.K. (1995). The ncl-1 gene and genetic mosaics of Caenorhabditis elegans. Genetics 141, 989-1006.
30. Hedgecock, E., Sulston, J., and Thomson, J.N. (1983). Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans. Science 220, 1277-1279.
31. Hengartner, M.O. (1997). Cell Death in C. elegans II, R.L. Riddle, T. Blumenthal, B.J. Meyer, and J.R. Priess, eds. (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press), pp. 383-415.
32. Higgins, C.F. (1992). ABC transporters: from microorganisms to man. Annu. Rev. Cell Biol. 8, 67-113.
33. Higgins, C.F., and Gottesman, M.M. (1992). Is the multidrug transporter a flippase? Trends Biochem. Sci. 17, 18-21.
34. Illing, M., Molday, L.L., and Molday, R.S. (1997). The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily. J. Biol. Chem. 272, 10303-10310.
35. Jacobson, M.D., Weil, M., and Raff, M.C. (1997). Programmed cell death in animal development. Cell 88, 347-354.
36. Kenyon, C. (1986). A gene involved in the development of the posterior body region of C. elegans. Cell 46, 477-487.
37. Kimble, J., and Hirsh, D. (1979). The postembryonic cell lineages of the hermaphrodite and male gonads in Caenorhabditis elegans. Dev. Biol. 70, 396-417.
38. Klugbauer, N., and Hofmann, F. (1996). Primary structure of a novel ABC transporter with a chromosomal localization on the band encoding the multidrug resistance-associated protein. FEBS Lett. 391, 61-65.
39. Krause, M., and Hirsh, D. (1987). A trans-spliced leader sequence on actin mRNA in C. elegans. Cell 49, 753-761.
40. Kyte, J., and Doolittle, R.F. (1982). A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157, 105-132.
41. Luciani, M.F., and Chimini, G. (1996). The ATP binding cassette transporter ABC1 is required for the engulfment of corpses generated by apoptotic cell death. EMBO J. 15, 226-235.
42. Luciani, M.F., Denizot, F., Savary, S., Mattei, M.G., and Chimini, G. (1994). Cloning of two novel ABC transporters mapping on human chromosome 9. Genomics 21, 150-159.
43. Mello, C.C., Kramer, J.M., Stinchcomb, D., and Ambros, V. (1992). Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10, 3959-3970.
44. Pai, E.F., Sachsenheimer, W., Schirmer, R.H., and Schulz, G.E. (1977). Substrate positions and induced-fit in crystalline adenylate kinase. J. Mol. Biol. 114, 37-45.
45. Rimm, D.L., and Pollard, T.D. (1989). New plasmid vectors for high level synthesis of eukaryotic fusion proteins in Escherichia coli. Gene 75, 323-327.
46. Ruetz, S., and Gros, P. (1994). Phosphatidylcholine translocase: a physiological role for the mdr2 gene. Cell 77, 1071-1081.
47. Ruvkun, G., Ambros, V., Coulson, A., Waterston, R., Sulston, J., and Horvitz, H.R. (1989). Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14. Genetics 121, 501-516.
48. Saraste, M., Sibbald, P.R., and Wittinghofer, A. (1990). The P-loop - a common motif in ATP-and GTP-binding proteins. Trends Biochem. Sci. 15, 430-434.
49. Savill, J. (1997). Apoptosis in resolution of inflammation. J. Leukoc. Biol. 61, 375-380.
50. Savill, J., Dransfield, I., Hogg, N., and Haslett, C. (1990). Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis. Nature 343, 170-173.
51. Savill, J., Hogg, N., and Haslett, C. (1991). Macrophage vitronectin receptor, CD36, and thrombospondin cooperate in recognition of neutrophils undergoing programmed cell death. Chest 99, 6S-7S.
52. Savill, J., Hogg, N., Ren, Y., and Haslett, C. (1992). Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. J. Clin. Invest. 90, 1513-1522.
53. Savill, J., Fadok, V., Henson, P., and Haslett, C. (1993). Phagocyte recognition of cells undergoing apoptosis. Immunol. Today 14, 131-136.
54. Seydoux, G., and Greenwald, I. (1989). Cell autonomy of lin-12 function in a cell fate decision in C. elegans. Cell 57, 1237-1245.
55. Smit, J.J.M., Schinkel, A.H., Oude Elferink, R.P.J., Groen, A.K., Wagenaar, E., van Deemter, L., Mol, C.A.A.M., Ottenhoff, R., van der Lugt, N.M.T., van Roon, M.A., et al. (1993). Homozygous disruption of the murine mdr2 p-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell 75, 451-462.
56. Steller, H. (1995). Mechanisms and genes of cellular suicide. Science 267, 1445-1449.
57. Stringham, E.G., Dixon, D.K., Jones, D., and Candido, E.P. (1992). Temporal and spatial expression patterns of the small heat shock (hsp16) genes in transgenic Caenorhabditis elegans. Mol. Biol. Cell 3, 221-333.
58. Sulston, J.E., and Horvitz, H.R. (1977). Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev. Biol. 56, 110-156.
59. Sulston, J.E., Schierenberg, E., White, J.G., and Thomson, J.N. (1983). The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev. Biol. 100, 64-119.
60. van Helvoort, A., Smith, A.J., Sprong, H., Fritzsche, I., Schinkel, A.H., Borst, P., and van Meer, G. (1996). MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine. Cell 87, 507-517.
61. Walker, J.E., Saraste, M., Runswick, M.J., and Gay, N.J. (1982). Distantly related sequences in the α-and β-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1, 945-951.
62. Wilson, R., Ainscough, R., Anderson, K., Baynes, C., Berks, M., Bonfield, J., Burton, J., Connell, M., Copsey, T., Cooper, J., et al. (1994). 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature 368, 32-38.
63. Williams, B.D., Schrank, B., Huynh, C., Shownkeen, R., and Waterston, R.H. (1992). A genetic-mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites. Genetics 131, 609-624.
64. Wu, Y.-C., and Horvitz, H.R. (1998). C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature 392, 501-504.