Feature selection for DNA methylation based cancer classification

Bioinformatics

Volumn 17, Issue SUPPL. 1, 2001, Pages

  Model, Fabian ^a   Adorján, Péter ^a   Olek, Alexander ^a   Piepenbrock, Christian ^a  

^a EPIGENOMICS AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; ARTICLE; BIOLOGY; CHEMISTRY; CLASSIFICATION; COMPARATIVE STUDY; CPG ISLAND; DNA METHYLATION; DNA MICROARRAY; HUMAN; METABOLISM; NEOPLASM; PRINCIPAL COMPONENT ANALYSIS; STATISTICS;

COMPUTATIONAL BIOLOGY; CPG ISLANDS; DNA METHYLATION; DNA, NEOPLASM; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKEMIA, MYELOCYTIC, ACUTE; NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS;

EID: 0035224384     PISSN: 13674803     EISSN: 13674811     Source Type: Journal    
DOI: 10.1093/bioinformatics/17.suppl_1.S157     Document Type: Article

References (16)

1. Adorján, P., Distler, J., Lipscher, E., Model, F., Müller, J., Pelet, C., Braun, A., Florl, A., Gütig, D., Grabs, G., Howe, A., Kursar, M., Lesche, R., Leu, E., Lewin, A., Maier, S., Müller, V., Otto, T., Scholz, C., Schulz, W., Seifert, H., Schwope, I., Ziebarth, H., Berlin, K., Piepenbrock, C. & Olek, A. (2001). Tumour class prediction and discovery by microarray-based dna methylation analysis. Submitted.
2. Ben-Dor, A., Bruhn, L., Friedman, N., Nachman, I., Schummer, M. & Yakhini, Z. (2001). Tissue classification with gene expression profiles. In Proceedings of the Fifth Annual Conference on Computational Molecular Biology. In press.
3. Bishop, C. (1995). Neural networks for pattern recognition. Oxford University Press, New York.
4. Blum, A. & Langley, P. (1997). Selection of relevant features and examples in machine learning. Artificial Intelligence, 97, 245-271.
5. Bowtell, D. (1999). Options available - from start to finish - for obtaining expression data by microarray. Nature Genetics suppl., 21, 25-32.
6. Brown, M., Grundy, W., Lin, D., Cristianini, N., Sugnet, C., Furey, T., Ares, M. & Haussler, D. (2000). Knowledge-based analysis of microarray gene expression data by using support vector machines. Proc. Natl. Acad. Sci. USA, 97, 262-267.
7. Christianini, N. & Shawe-Taylor, J. (2000). An Introduction to Support Vector Machines. Cambridge University Press, Cambridge.
8. Emmert-Buck, M., Strausberg, R., Krizman, D., Bonaldo, M., Bonner, R., Bostwick, D., Brown, M., Buetow, K., Chuaqui, R., Cole, K., Duray, P., Englert, C., Gillespie, J., Greenhut, S., Grouse, L., Hillier, L., Katz, K., Klausner, R., Kuznetzov, V., Lash, A., Lennon, G., Linehan, W., Liotta, L., Marra, M., Munson, P., Ornstein, D., Prabhu, V., Prange, C., Schuler, G., Soares, M., Tolstoshev, C., Vocke, C. & Waterston, R. (2000). Molecular profiling of clinical tissue specimens: feasibility and applications. Am. J. Pathol., 156, 1109-1115.
9. Frommer, M., McDonald, L., Millar, D., Collis, C., Watt, F., Grigg, G., Molloy, P. & Paul, C. (1992). A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc. Natl. Acad. Sci. USA, 89, 1827-1831.
10. Gaasterland, T. & Bekiranov, S. (2000). Making the most of microarry data. Nature Genetics, 24, 204-206.
11. Golub, T., Slonim, D., Tamayo, P., Huard, C., Gaasenbeek, M., Mesirov, J., Coller, H., Loh, M., Downing, J., Caligiuri, M., Bloomfield, C. & Lander, E. (1999). Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring. Science, 286, 531-537.
12. Lockhart, D. & Winzeler, E. (2000). Genomics, gene expression and DNA arrays. Nature, 405, 827-836.
13. Mendenhall, W. & Sincich, T. (1995). Statistics for engineering and the sciences. Prentice-Hall, New Jersey.
14. Robertson, K. & Wolffe, A. (2000). DNA methylation in health and disease. Nature Reviews Genetics, 1, 11-19.
15. Vapnik, V. (1998). Statistical Learning Theory. Wiley, New York.
16. Weston, J., Mukherjee, S., Chapelle, O., Pontil, M., Poggio, T. & Vapnik, V. (2001). Feature selection for SVMs. In Advances in Neural Information Processing Systems, volume 13. MIT Press, Cambridge, MA. In press.