Involvement of BMP-2 signaling in a cartilage cap in osteochondroma

Journal of Orthopaedic Research

Volumn 19, Issue 6, 2001, Pages 1085-1088

  Nakase, Takanobu ^a   Myoui, Akira ^a   Shimada, Kozo ^a   Kuriyama, Kohji ^a   Joyama, Susumu ^a   Miyaji, Takahiro ^a   Tomita, Tetsuya ^a   Yoshikawa, Hideki ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; CARTILAGE; CELLS; COLLAGEN; HISTOLOGY; RNA;

CARTILAGENOUS MATRIX;

ORTHOPEDICS;

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTOR; BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE IB; COLLAGEN TYPE 2; COLLAGEN TYPE 3; MESSENGER RNA; UNCLASSIFIED DRUG;

ARTICLE; CARTILAGE CELL; CARTILAGE MATRIX; CASE REPORT; CHILD; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MESENCHYME CELL; NUCLEOTIDE SEQUENCE; OSTEOCHONDROMA; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEINS; BONE NEOPLASMS; CARTILAGE; CHILD; CHILD, PRESCHOOL; COLLAGEN; FEMALE; HUMANS; MALE; OSTEOCHONDROMA; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, GROWTH FACTOR; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 0035215792     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0736-0266(01)00041-9     Document Type: Article

References (34)

1. Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage
2. Bone morphogenetic protein (BMP) localization in developing human and rat growth plate, metaphysis, epiphysis, and articular cartilage
3. Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone
4. The identity of proliferating cells in bone tumors with cartilaginous components: Evaluation by double-immunohistochemical staining using proliferating cell nuclear antigen and S-100 protein
5. Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: I. Stimulation by bone morphogenetic protein-2 in high-density micromass cultures
6. Solitary osteocartilaginous exostosis (osteochondroma)
7. Developmental patterning in chondrocytic cultures by morphogenic gradients: BMP induces expression of indian hedgehog and noggin
8. Bone Morphogenetic Proteins
9. Rapid chondrocyte maturation by serum-free culture with BMP-2 and ascorbic acid
10. Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development
11. Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development
12. Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A)
13. Role of BMP-2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development
14. Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling
15. Expression of c-met proto-oncogene product (c-MET) in benign and malignant bone tumors
16. Transient and localized expression of bone morphogenetic protein 4 messenger RNA during fracture healing
17. Interaction of Ihh and BMP/Noggin signaling during cartilage differentiation
18. P-glycoprotein expression in cartilaginous tumors
19. Treatment of resting zone chondrocytes with bone morphogenetic protein-2 induces maturation into a phenotype characteristic of growth zone chondrocytes by downregulating responsiveness to 24, 25(OH)2D3 and responsiveness to 1, 25-(OH)2D3
20. The effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the healing of full-thickness defects of articular cartilage
21. Repair of articular cartilage defects one year after treatment with recombinant human bone morphogenetic protein-2 (rhBMP-2)
22. Sequential progression of the differentiation program by bone morphogenetic protein-2 in chondrogenic cell line ATDC5
23. Bone: Formation by autoinduction
24. Modulation of chondrocyte proliferation by ascorbic acid and BMP-2
25. Utilization of bone morphogenetic protein receptors during chondrocyte maturation
26. Recapitulation of signals regulating embryonic bone formation during postnatal growth and in fracture repair
27. S-100 protein in human cartilage lesions
28. Novel regulators of bone formation: Molecular clones and activities
29. The type I BMP receptor BMPRIB is required for chondrogenesis in the mouse limb
30. Immunohistochemical detection of bone morphogenetic proteins in bone and soft-tissue sarcomas
31. Expression of bone morphogenetic proteins in human osteosarcoma. Immunohistochemical detection with monoclonal antibody
32. Bone formation with use of rhBMP-2 (recombinant human bone morphogenetic protein-2
33. Targeted misexpression of constitutively active BMP receptor-IB causes bifurcation, duplication, and posterior transformation of digit in mouse limb
34. Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage