Expression of bilirubin UDP-glucuronosyltransferase (bUGT) throughout fetal development: Intrasplenic transplantation into Gunn rats to correct enzymatic deficiency

Digestive Diseases and Sciences

Volumn 46, Issue 12, 2001, Pages 2762-2767

  Cubero, F J ^a   Arza, E ^a   Maganto, P ^b   Barrutia, García ^a   Mula, N ^b   Ortiz, A ^a   Arahuetes, R M ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b HOSPITAL UNIVERSITARIO PUERTA DE HIERRO   (Spain)

Author keywords

Bilirubin UDP glucuronosyltransferase; Fetal hepatocyte transplantation; Gunn rats; Hyperbilirubinemia

Indexed keywords

ALPHA FETOPROTEIN; BILIRUBIN GLUCURONIDE; GLUCURONOSYLTRANSFERASE; MESSENGER RNA;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL TRANSPLANTATION; CONTROLLED STUDY; ENZYME DEFICIENCY; FETUS; FETUS CELL; FETUS DEVELOPMENT; FETUS LIVER; FETUS WEIGHT; GENE EXPRESSION; HYPERBILIRUBINEMIA; LIVER WEIGHT; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN;

ANIMALS; ANIMALS, NEWBORN; BILIRUBIN; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; FETAL WEIGHT; GENE EXPRESSION; GESTATIONAL AGE; GLUCURONOSYLTRANSFERASE; HEPATOCYTES; RATS; RATS, GUNN; RATS, WISTAR;

EID: 0035215404     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012743916800     Document Type: Article

References (20)

1. Bilirubin metabolism and its disorders
2. Mechanism of the lack of induction of UDP glucuronosyltransferase activity by 3-methylcholanthrene in Gunn rats: The two isoforms are encoded by distinct mRNA species that share an identical single base deletion
3. Genetic defect of bilirubin UDP-glucuronosyltransferase in the hyperbilirubinemic Gunn rat
4. Mechanism of the lack of induction of UDP-glucuronosyltransferase activity by 3-methylcholanthrene in Gunn rats
5. Foreword: Prospects of liver cell transplantation and liver-directed gene therapy
6. Hepatocyte transplantation for the treatment of liver disease
7. Transplantation of liver cells in an animal model of congenital enzyme deficiency disease: The Gunn rat
8. Optimization of the technique to isolate fetal hepatocytes and assessment of their functionality by transplantation
9. Antioxidant enzymatic activities in fetal hepatocytes transplanted into spleen
10. High yield preparation of isolated rat liver parenchymal cells: A biochemical and fine study
11. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
12. Selective detection of rat and mouse specific albumin and α-phetoprotein mRNA molecules under highly stringent hybridization conditions
13. Isolation and sequencing of rat liver bilirubin-UDP-glucuronosyltransferase cDNA: Possible alternate splicing of a common primary transcript
14. An experimental analysis of liver development
15. Growth and differentiation of adult rat hepatocytes regulated by the interaction between parenchymal and nonparenchymal liver cells
16. Alphafetoprotein in ontogenesis and its association with malignant tumors
17. Prenatal diagnosis of bilirubin-UDP-glucuronosyltransferase deficiency in rats by genomic DNA analysis
18. Expansion conditions for hepatic progenitor cells from embryonal and neonatal rat livers
19. Perinatal development of bilirubin UDP-glycosyltransferase activities in rat liver
20. Bilirubin, UDP-glucuronyl transferase of liver in postmature rats. A functional and morphologic comparison