A growth and differentiation factor-5 (GDF-5)-coated suture stimulates tendon healing in an Achilles tendon model in rats

Growth Factors

Volumn 19, Issue 2, 2001, Pages 115-126

  Rickert, M ^a   Jung, M ^a   Adiyaman, M ^a   Richter, W ^a   Simank, H G ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Growth and differential factors; Tendon healing

Indexed keywords

ABSORBABLE SUTURE; COLLAGEN TYPE 2; GROWTH DIFFERENTIATION FACTOR 5; POLYGLACTIN; SUTURE MATERIAL;

ACHILLES TENDON; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE DEVELOPMENT; CONTROLLED STUDY; HEALING; HISTOLOGY; LIGAMENT; MALE; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZATION; RAT; RIGIDITY; SUTURE; TENDON; TENDON RECONSTRUCTION; TENSILE STRENGTH; THICKNESS; TISSUE REPAIR;

EID: 0035214915     PISSN: 08977194     EISSN: None     Source Type: Journal    
DOI: 10.3109/08977190109001080     Document Type: Article

References (28)

1. "Enhanced tendon healing with GDF 5 and 6"
2. "Achilles tendon healing: A correlation between functional and mechanical performance in the rat"
3. "Biomechanics of ligaments and tendons"
4. "Cartilage-derived morphogenetic proteins: New members of the transforming growth factors-β superfamily predominantly expressed in long bones during human embryonic development"
5. "Cartilage-derived morphogenetic protein and osteogenetic protein-1 differentially regulate osteogenesis"
6. "The effect of overexpression of BMPs and GDF-5 on the development of chick limb skeletal elements"
7. "Mechanism of GDF-5 action during skeletal development"
8. Biomechanics-Mechanical properties of living tissues
9. "Recombinant human growth/differentiation factor 5 stimulates mesenchyme aggregation and condrogenesis responsible for the skeletal development of limbs"
10. "In vitro effects of epidermal growth factor or insulin like growth factor on tenoblast migration on absorbable suture material"
11. "Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections"
12. "Trophic and protective effects of growth/differentiation factor 5, a member of the transforming growth factor-β superfamily, on midbrain dopaminergic neurons"
13. "Midbrain dopaminergic neurons are protected from radical damage by GDF-5 application"
14. "Cartilage-derived morphogenetic protein-1"
15. "Achilles tendon injuries: A comparison of surgical repair versus no repair in a rat model"
16. "Mersilene suture as a vehicle for delivery of growth factors in tendon repair"
17. "Enchondral ossification and de nova collagen synthesis during repair of the rat Achilles tendon"
18. "Cartilage and bone formation in repairing Achilles tendons within diffusion chambers: Evidence for tendon-cartilage and cartilage-bone conversion in vivo"
19. "Limb alterations in brachypodism mice due to mutations in a new member of the TGF-β superfamily"
20. "Growth/differentiation factor 5 and glial cell line-derived neurotrophic factor enhance survival and function of dopaminergic grafts in a rat model of Parkinson's disease"
21. "Growth and differentiation factor-5 promotes the repair process of medial collateral ligaments in rats"
22. "A human chondrodysplasia due to a mutation in a TGF-β superfamily member"
23. "Disruption of human limb morphogenesis by a dominant negative mutation in CDMP-1"
24. "In situ measurement of collagen synthesis by human bone cells with a Sirius Red-based calorimetric microassay: Effects of transforming growth factor-β2 and ascorbic acid 2-phosphate"
25. "Changes in tensile characteristics and histology of rabbit ligaments induced by different modes of postmortal storage"
26. "Ectopic induction of tendon and ligament in rats by growth and differentiation factor 5, 6, and 7, members of the TGF-β gene family"
27. "Structure and function of tendons and ligaments"
28. "Growth/differentiation factor-5 induces angiogenesis in vivo"