Randomized, placebo-controlled trial of gastric acid-lowering therapy on duodenal polyposis and relative adduct labeling in familial adenomatous polyposis

Diseases of the Colon and Rectum

Volumn 44, Issue 11, 2001, Pages 1585-1589

  Wallace, M H ^a   Forbes, A ^a   Beveridge, I G ^a   Spigelman, A D ^a   Hewer, A ^a   Venitt, S ^a   Phillips, R K S ^a  

^a ST MARK S HOSPITAL   (United Kingdom)

Author keywords

Bile; DNA adducts; Familial adenomatous polyposis; PH

Indexed keywords

ANTACID AGENT; PHOSPHORUS 32; RANITIDINE;

ADENOMATOUS POLYP; ADULT; ARTICLE; BILE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE MARKER; DNA ADDUCT; DUODENUM BIOPSY; DUODENUM POLYP; ENDOSCOPY; FAMILIAL DISEASE; FEMALE; HUMAN; MALE; PH; POLYPOSIS; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADENOMATOUS POLYPOSIS COLI; ADMINISTRATION, ORAL; ADULT; ANTI-ULCER AGENTS; BILE; DNA ADDUCTS; DOUBLE-BLIND METHOD; DUODENAL NEOPLASMS; ENDOSCOPY; FEMALE; GASTRIC ACID; HUMANS; INTESTINAL POLYPS; MALE; RANITIDINE; TREATMENT OUTCOME;

EID: 0035213007     PISSN: 00123706     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02234376     Document Type: Article

References (23)

1. Upper gastrointestinal cancer in patients with familial adenomatous polyposis
2. The risk of upper gastrointestinal cancer in familial adenomatous polyposis
3. Surgical treatment of severe duodenal polyposis in familial adenomatous polyposis
4. Familial adenomatous polyposis: Efficacy of endoscopic and surgical treatment for advanced duodenal adenomas
5. 32P-postlabeling test for structurally diverse DNA adducts
6. 32P-labeling test for DNA damage
7. 32P-postlabelling, in the foregut of patients with familial adenomatous polyposis and in unaffected controls
8. 32P-postlabelling, in the intestine of rats given bile from patients with familial adenomatous polyposis and from unaffected controls
9. 32P-postlabelling, in DNA treated in vitro with bile from patients with familial adenomatous polyposis and from unaffected controls
10. Searches for ultimate chemical carcinogens and their reactions with cellular macromolecules
11. High pH reduces DNA damage caused by bile from patients with familial adenomatous polyposis: Antacids may attenuate duodenal polyposis
12. Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis
13. Prospective randomized study of sulindac versus calcium and calciferol for upper gastrointestinal polyps in familial adenomatous polyposis
14. Evidence for adenoma-carcinoma sequence in the duodenum of patients with familial adenomatous polyposis
15. The natural history of untreated duodenal and ampullary adenomas in patients with familial adenomatous polyposis followed in an endoscopic surveillance program
16. Photodynamic therapy for polyposis in familial adenomatous polyposis
17. Surgical polypectomy of duodenal adenomas in familial adenomatous polyposis: An experience of two European centres
18. Effect of sulindac on small polyps in familial adenomatous polyposis
19. Interaction of omeprazole with DNA in rat tissue
20. Fundic gland polyps developing during omeprazole therapy
21. Effect of omeprazole 40 mg once daily on intraduodenal and intragastric pH in H. pylori negative healthy subjects
22. Glutathione S-transferase Mu phenotype in patients with familial adenomatous polyposis and in unaffected controls
23. 32P-postlabelling in studies of the nature and origin of DNA adducts formed by bile from patients with familial adenomatous polyposis and from normal patients