Prospective randomized study of sulindac versus calcium and calciferol for upper gastrointestinal polyps in familial adenomatous polyposis

British Journal of Surgery

Volumn 83, Issue 12, 1996, Pages 1763-1766

  Seow Choen, F ^a   Vijayan, V ^a   Keng, V ^a  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; ERGOCALCIFEROL; NONSTEROID ANTIINFLAMMATORY AGENT; SULINDAC;

ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COLON RESECTION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; FAMILIAL COLON POLYPOSIS; HUMAN; HUMAN TISSUE; INTESTINE CRYPT; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STOMACH EPITHELIUM;

EID: 0029750326     PISSN: 00071323     EISSN: None     Source Type: Journal    
DOI: 10.1002/bjs.1800831232     Document Type: Article

References (23)

1. Goodman AJ, Dundas SAC, Scholefield JH, Johnson BF. Gastric carcinoma and familial adenomatous polyposis (FAP). Int J Colorectal Dis 1988; 3: 201-3.
2. Seow-Choen F, Ho JMS, Wong J, Goh HS. Gross and histological abnormalities of the foregut in familial adenomatous polyposis: a study from a South East Asian Registry. Int J Colorectal Dis 1992; 7: 177-83.
3. Arvanitis MC, Jagelman DG, Fazio VW, Lavery IC, McGannon E. Mortality in patients with familial adenomatous polyposis. Dis Colon Rectum 1990; 33: 639-42.
4. Thomas MG, Thomson JPS, Williamson RCN. Oral calcium inhibits rectal epithelial proliferation in familial adenomatous polyposis. Br J Surg 1993; 80: 449-501.
5. Lipkin M, Newmark H. Effect of added dietary calcium on colonie epithelial-cell proliferation in subjects at high risk for familial colonic cancer. N Engl J Med 1985; 313: 1381-4.
6. Garland C, Barrett-Connor ER, Shekelle RB, Criqui MH, Paul O. Dietary vitamin D and calcium and risk of colorectal cancer: a 19-year prospective study in men. Lancet 1985; i: 307-9.
7. Thomas MG, Tebbutt S, Williamson RCN. Vitamin D and its metabolites inhibit cell proliferation in human rectal mucosa and a colon cancer cell line. Gut 1992; 33: 1660-3.
8. Thomas MG, Brown GR, Alison MR, Williamson RCN. Divergent effects of epidermal growth factor and calcipotriol on human rectal cell proliferation. Gut 1994; 35: 1742-6.
9. Waddell WR, Ganser GF, Cerise EJ, Loughry RW. Sulindac for polyposis of the colon. Am J Surg 1989; 157: 175-9.
10. Giardiello FM, Hamilton ST, Krush AJ et al. Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N Engl J Med 1993; 328: 1313-16.
11. Winde G, Gumbinger HG, Osswald H, Kemper F, Bunte H. The NSAID sulindac reverses rectal adenomas in colectomized patients with familial adenomatous polyposis: clinical results of a dose-finding study on rectal sulindac administration. Int J Colorectal Dis 1993; 8: 13-17.
12. Labayle D, Fischer D, Vielh P et al. Sulindac causes regression of rectal polyps in familial adenomatous polyposis. Gastroenterology 1991; 101: 635-9.
13. Gonzaga RAF, Lima FR, Carneiro S, Maciel J, Amarante-Junior M. Sulindac treatment for familial polyposis coli. Lancet 1985; i: 751 (Letter).
14. Iwana T, Imajo M, Mishima Y. Is sulindac effective for familial adenomatous polyposis? Int J Colorectal Dis 1991; 6: 235.
15. Lipkin M. Biomarkers of increased susceptibility to gastrointestinal cancer: new application to studies of cancer prevention in human subjects. Cancer Res 1988; 48: 235-45.
16. Bertram JS. Prospects for the chemoprevention of cancer in humans. In: Herrera L, ed. Familial Adenomatous Polyposis. New York: Alan R Liss, 1990: 253-62.
17. Desigan G, Wang M, Dunn D, Halter S, Vaughan S. Intramucosal gastric carcinoma in a patient with familial polyposis coli. Am J Gastroenterol 1986; 81: 19-22.
18. Nugent KP, Farmer KCR, Spigelman AD, Williams CB, Phillips RKS. Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis. Br J Surg 1993; 80: 1618-19.
19. Appleton GVN, Davies PW, Bristol JB, Williamson RCN. Inhibition of intestinal carcinogenesis by dietary supplementation with calcium. Br J Surg 1987; 74: 523-5.
20. Utsunomiya J, Maki T, Iwama T et al. Gastric lesion of familial polyposis coli. Cancer 1974; 34: 745-54.
21. 3 in the proliferation of a human colon cancer cell line in vitro. Anticancer Res 1987; 7: 817-22.
22. Colston KW, Berger U, Coombes RC. Possible role for vitamin D in controlling breast cancer proliferation. Lancet 1989; i: 188-91.
23. Friedman E, Lipkin M, Winawer S, Buset M, Newmark H. Heterogenicity in the response of familial polyposis epithelial cells and adenomas to increasing levels of calcium in vitro. Cancer 1989; 63: 2486-91.