Clinical activity of the new triazole drug voriconazole (UK 109, 496) against disseminated hepatosplenic aspergillosis in a patient with relapsed leukemia

Haematologia

Volumn 31, Issue 1, 2001, Pages 73-80

  Hwang, Y K W ^a   Joo, N H ^a   Tee, G Y ^a   Tan, P ^a   Tan, L ^a   Girija, R ^a  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

Acute leukemia; Antifungal therapy; Disseminated aspergillosis; Voriconazole

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B LIPID COMPLEX; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; BICARBONATE; CYTARABINE; FLUCONAZOLE; FLUDARABINE; GRANULOCYTE COLONY STIMULATING FACTOR; IDARUBICIN; ITRACONAZOLE; METHYLPREDNISOLONE; PYRROLE DERIVATIVE; RETINOIC ACID; TOPOTECAN; TRIAZOLE DERIVATIVE; VORICONAZOLE;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLOSIS; ASPERGILLUS; CANCER CHEMOTHERAPY; CANCER RECURRENCE; CANDIDA; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; HUMAN; IN VITRO STUDY; INFECTION CONTROL; LIVER DISEASE; MALE; NEPHROTOXICITY; REVIEW; SPLEEN DISEASE; TREATMENT FAILURE;

ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS; ASPERGILLOSIS; CHILD; HUMANS; IMMUNOSUPPRESSION; LEUKEMIA, MYELOID; LIVER DISEASES; MALE; PYRIMIDINES; SPLENIC DISEASES; TRIAZOLES;

EID: 0035210901     PISSN: 00176559     EISSN: None     Source Type: Journal    
DOI: 10.1163/15685590151092742     Document Type: Article

References (9)

1. Progress in righting systemic fungal infections in haematological neoplasia
2. Antifungal activity of the new azole UK-109, 496 (voriconazole)
3. Antifungal acitivity of a new triazole, voriconazole (UK-109, 496), compared with three other antifungal agents tested against clinical isolates of filamentous fungi
4. In vitro activity of the new triazole, voriconazole (UK-109, 496) against opportunistic filamentous and dimorphic fungi and common and emerging yeast pathogens
5. In vitro susceptibilities of Aspergillus species to voriconazole, itraconazole and amphotericin B
6. In vitro studies of activity of voriconazole (UK-109, 496), a new triazole antifungal agent, against emerging and less common mould pathogens
7. Successful treatment with voriconazole of invasive aspergillosis in chronic granulomatous disease
8. A patient with acute leukemia who developed an Aspergillus brain abscess was successfully treated with voriconazole
9. Skull base osteitis following fungal sinusitis