In vitro studies of activity of voriconazole (UK-109,496), a new triazole antifungal agent, against emerging and less-common mold pathogens

Antimicrobial Agents and Chemotherapy

Volumn 41, Issue 4, 1997, Pages 841-843

  Radford, Sarah A ^a   Johnson, Elizabeth M ^a   Warnock, David W ^a  

^a Public Health Laboratory   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ITRACONAZOLE; VORICONAZOLE;

ANTIFUNGAL ACTIVITY; ARTICLE; DRUG EFFICACY; DRUG POTENCY; FUSARIUM; MYCOSIS; PENICILLIUM MARNEFFEI; PRIORITY JOURNAL;

EID: 0030985567     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.4.841     Document Type: Article

References (18)

1. Denning, D. W., A. del Favero, E. Gluckman, D. Norfolk, M. Ruhnke, S, Yonren, P. F. Troke, and N. Sarantis. 1995. UK-109,496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: clinical efficacy in acute invasive aspergillosis, abstr. F80, p. 126. In Program and abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
2. Dupont, B., D. Denning, H. Lode, S. Yonren, P. F. Troke, and N. Sarantis. 1995. UK-109,496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: clinical efficacy in chronic invasive aspergillosis, abstr. F81, p. 127. In Program and abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
3. Espinel-Ingroff, A., K. Dawson, M. Pfaller, E. Anaissie, B. Breslin, D. Dixon, A. Fothergill, V. Paetznick, J. Peter, M. Rinaldi, and T. Walsh. 1995. Comparative and collaborative evaluation of standardization of antifungal susceptibility testing for filamentous fungi. Antimicrob. Agents Chemother. 39:314-319.
4. Garnis, A. S., T. Gudnason, G. S. Giebink, and N. K. C. Ramsay. 1991. Disseminated infection with fusarium in recipients of bone marrow transplants. Rev. Infect. Dis. 13:1077-1088.
5. Gehrt, A., J. Peter, P. A. Pizzo, and T. J. Walsh. 1995. Effect of increasing inoculum sizes of pathogenic filamentous fungi on MICs of antifungal agents by broth microdilution method. J. Clin. Microbiol. 33:1302-1307.
6. George, D., P. Miniter, and V. T. Andriole. 1996. Efficacy of UK-109496, a new azole antifungal agent, in an experimental model of invasive aspergillosis. Antimicrob. Agents Chemother. 40:86-91.
7. Hitchcock, C. A., R. J. Andrews, B. G. H. Lewis, and P. F. Troke. 1995. UK-109,496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: antifungal activity in experimental infections with Aspergillus, abstr. F74, p. 125. In Program and abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
8. Hitchcock, C. A., R. J. Andrews, B. G. H. Lewis, and P. F. Troke. 1995. UK-109,496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: antifungal activity in experimental infections with Cryptococcus, abstr. F75, p. 126. In Program and abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
9. Hitchcock, C. A., G. W. Pye, G. P. Oliver, and P. F. Troke. 1995. UK-109,496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: antifungal activity and selectivity in vitro, abstr. F72, p. 125. In Program and abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
10. Hopwood, V., E. G. V. Evans, J. Matthews, and D. W. Denning. 1995. Scedosporium prolificans, a multi-resistant fungus, from a U.K. AIDS patient. J. Infect. 30:153-155.
11. Lutwick, L. I., J. N. Galgiani, R. H. Johnson, and D. A. Stevens. 1976. Visceral fungal infections due to Petriellidium boydii (Allescheria boydü). In vitro drug sensitivity studies. Am. J. Med. 61:632-640.
12. National Committee for Clinical Laboratory Standards. 1995. Reference method for broth dilution antifungal susceptibility testing of yeasts. Tentative standard M27-T. National Committee for Clinical Laboratory Standards, Wayne, Pa.
13. Patterson, B. E., and P. E. Coates. 1995. UK-109,496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: pharmacokinetics in man, abstr. F78, p. 126. In Program and abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
14. Patterson, B. E., S. Roffey, S. G. Jezequel, and B. Jones. 1995. UK-109,496, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: disposition in man, abstr. F79, p. 126. In Program and abstracts of the 35th Intersciencc Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
15. Rodriguez-Tudela, J. L., J. V. Martinez-Suarez, F. Dronda, F. Laguna, F. Chaves, and E. Valencia. 1995. Correlation of in-vitro susceptibility test results with clinical response: a study of azole therapy in AIDS patients. J. Antimicrob. Chemother. 35:793-804.
16. Troke, P. F., K. W. Brammer, C. A. Hitchcock, S. Yonren, and N. Sarantis. 1995. UK-109,490, a novel, wide-spectrum triazole derivative for the treatment of fungal infections: activity in systemic candidiasis models and early clinical efficacy in oropharyngeal candidiasis, abstr. F73, p. 125. In Program and abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
17. Valentin, A., R. Le Guennec, E. Rodriguez, J. Reynes, M. Mallie, and J. M. Bastide. 1996. Comparative resistance of Candida albicans clinical isolates to fluconazole and itraconazole in vitro and in vivo in a murine model. Antimicrob. Agents Chemother. 40:1342-1345.
18. Velez, J. D., R. Allendoerfer, M. Luther, M. G. Rinaldi, and J. R. Graybill. 1993. Correlation of in vitro azoic susceptibility with in vivo response in a murine model of cryptococcal meningitis. J. Infect. Dis. 168:508-510.